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MBF Bioscience Blog

MBF Bioscience >  Blog
February 11, 2021

Visualize and Quantify Dendritic Spine Morphology Over Time with the New Release of MicroDynamix™Software

by Pasang
in Software Applications For Quantitive Analysis, Company News, MicroDynamix®, Press Release, MBF Products & Service Solutions, Additional Subject Matter
Comments

For Immediate Release Williston, VT (February 11th, 2021)—MicroDynamix™software version 2021 is now available. This state-of-the-art dendritic-spine analysis application enables users to visualize and quantify spine morphology over time using powerful algorithms and detection methods.   Developed with input and support from the National Institute of Mental Health (NIMH), the new version of MicroDynamix software makes it easier than ever for neuroscientists to obtain accurate 4D dynamic analyses...

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December 10, 2020

MBF Bioscience Release ClearScope, Revolutionary Light Sheet Microscope for Imaging Large and Small Cleared Tissue Specimens

by Pasang
in ClearScope®, Company News, Scientific Applications & Use Cases, Press Release, MBF Products & Service Solutions, Microscopy Imaging Systems, Cleared Tissue and Whole Organ Research, Additional Subject Matter, Light Sheet
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For Immediate Release  Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D.     The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...

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December 10, 2020

NeuroInfo — New Release Features Faster Image Load and Deep Learning Cell Detection

by Pasang
in Company News, Software Applications For Quantitive Analysis, Press Release, MBF Products & Service Solutions, NeuroInfo®, Additional Subject Matter
Comments

For Immediate Release   Williston, VT (December 10, 2020) —NeuroInfo®is the most advanced software for mapping brain sections, 3D volumes and cell populations into a standardized atlas reference space.    Optimized to enable researchers to work far more efficiently, the new NeuroInfo update means faster, more efficient measurements and mapping workflows.    The new version of NeuroInfo includes:  Identification and delineation of brain regions in experimental mouse-brain sections  Automatic cell detection using deep learning to recognize and count specific neuronal subtypes  Performance optimizations that...

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December 1, 2020

MBF Bioscience Congratulates Dr. Bob Jacobs on His 30-Year Career

by Pasang
in Company News, Additional Subject Matter
Comments

Dr. Bob Jacobs has traced his 5,000th and final neuron. “It’s a good stopping point I think,” says the long-time MBF Bioscience customer, collaborator, and friend, who is retiring from research in December.   Dr. Jacobs has made significant advances in the fields of neuroanatomy and neuroethology over the course of his 30-year career. And the team at MBF Bioscience is grateful for the collaborative relationship we’ve...

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November 10, 2020

Researchers Observe Altered Neuropathology in CTE Brains

by Pasang
in Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, Alzheimer’s Disease, 3D Reconstruction
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Researchers at Colorado College may have identified a new neuropathological hallmark of Chronic Traumatic Encephalopathy (CTE). Their findings, published in the Journal of Comparative Neurology, describe overall dendritic atrophy across cortical neurons and greater morphological variability in CTE brains compared to controls.   A neurodegenerative disorder characterized by late-onset symptoms like depression, confusion, and memory loss, CTE is caused by repeated impacts to the brain. The disease...

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October 6, 2020

MicroFile+ Free Software for Converting Big Scientific Images into Manageable, Shareable, Standardized Files

by Pasang
in Company News, MicroFile+, Press Release, MBF Products & Service Solutions, Big Image Data Management Solutions, Additional Subject Matter
Comments

For Immediate Release: Williston, VT — October 6, 2020 — Big science produces big data. At laboratories around the world, researchers from every scientific discipline face a similar problem — how to manage the massive image files generated by large-scale experimental imaging workflows.   MBF Bioscience has solved this problem by leveraging our scientific imaging expertise to produce MicroFile+, a freely available software tool for the scientific community....

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September 25, 2020

MBF Bioscience Releases our File Format to Embrace FAIR Data Standards

by Pasang
in Company News, Press Release, MicroFile+, MBF Products & Service Solutions, Big Image Data Management Solutions, Additional Subject Matter
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For Immediate Release: Williston, VT (September 25, 2020)—To support the scientific community’s movement toward a more open and collaborative climate, MBF Bioscience is making their digital reconstruction file format, the Neuromorpholocial File Specification open and available to all researchers.   MBF Bioscience has a long history of supporting openness and collaboration in neuroscience research. MBF Bioscience’s file format has evolved for over 30 years, influenced by leading neuroscientists,...

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September 23, 2020

Curcumin Lowers Neuroinflammation in Mouse Model

by Pasang
in Software Applications For Quantitive Analysis, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®360, Alzheimer’s Disease
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Scientists at Western Sydney University used Stereo Investigator and Neurolucida 360 to quantify cells in a mouse model of neuroinflammation after feeding mice two different curcumin formulations. Some inflammation is normal in a healthy mammalian brain. But as the brain ages, processes can break down, leading to chronic neuroinflammation. This can develop into Alzheimer’s disease, dementia, and other neurodegenerative diseases.   Scientists at Prof. Gerald Muench’s lab, at...

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September 2, 2020

A method of mapping atlas information to a histological section image of a histological section

by Pasang
in Software Applications For Quantitive Analysis, Company News, MBF Products & Service Solutions, BrainMaker®, NeuroInfo®, Additional Subject Matter
Comments

MBF Bioscience was just awarded a patent by the USPTO for our new brain mapping technology! This novel technology is now available in our BrainMaker and NeuroInfo software to map image data and all associated measurements into a common coordinate system so that data can be compared across animals, cohorts, and laboratories. Learn more about NeuroInfo at https://www.mbfbioscience.com/neuroinfo    ...

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July 1, 2020

New Therapy May Aid Heart Repair After Heart Attack

by Pasang
in Software Applications For Quantitive Analysis, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Vesselucida®360, Vesselucida®Explorer
Comments

Researchers Quantify Improvement in Heart Vasculature with Vesselucida 360 and Vesselucida Explorer Cells need oxygen to survive, but during a heart attack, blood flow is restricted and cardiac cells can’t get the oxygen they need to stay alive. A new therapy, developed by researchers at the Coulombe Lab at Brown University may be able to provide the heart with the support it needs to recover after...

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