We suspect 2020 will always be remembered as the year of big, unexpected questions. Questions like, “How will we do our work together if we’re all working from our homes?" “When will we be able to move around freely again?” “How quickly will the economy bounce back post pandemic?” Questions like these have challenged each and every one of us to remain optimistic, curious, and mindful about what the...
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For Immediate Release Williston, VT (February 11th, 2021)—MicroDynamix™software version 2021 is now available. This state-of-the-art dendritic-spine analysis application enables users to visualize and quantify spine morphology over time using powerful algorithms and detection methods. Developed with input and support from the National Institute of Mental Health (NIMH), the new version of MicroDynamix software makes it easier than ever for neuroscientists to obtain accurate 4D dynamic analyses...
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For Immediate Release Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D. The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...
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For Immediate Release Williston, VT (December 10, 2020) —NeuroInfo®is the most advanced software for mapping brain sections, 3D volumes and cell populations into a standardized atlas reference space. Optimized to enable researchers to work far more efficiently, the new NeuroInfo update means faster, more efficient measurements and mapping workflows. The new version of NeuroInfo includes: Identification and delineation of brain regions in experimental mouse-brain sections Automatic cell detection using deep learning to recognize and count specific neuronal subtypes Performance optimizations that...
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Dr. Bob Jacobs has traced his 5,000th and final neuron. “It’s a good stopping point I think,” says the long-time MBF Bioscience customer, collaborator, and friend, who is retiring from research in December. Dr. Jacobs has made significant advances in the fields of neuroanatomy and neuroethology over the course of his 30-year career. And the team at MBF Bioscience is grateful for the collaborative relationship we’ve...
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Researchers at Colorado College may have identified a new neuropathological hallmark of Chronic Traumatic Encephalopathy (CTE). Their findings, published in the Journal of Comparative Neurology, describe overall dendritic atrophy across cortical neurons and greater morphological variability in CTE brains compared to controls. A neurodegenerative disorder characterized by late-onset symptoms like depression, confusion, and memory loss, CTE is caused by repeated impacts to the brain. The disease...
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For Immediate Release: Williston, VT — October 6, 2020 — Big science produces big data. At laboratories around the world, researchers from every scientific discipline face a similar problem — how to manage the massive image files generated by large-scale experimental imaging workflows. MBF Bioscience has solved this problem by leveraging our scientific imaging expertise to produce MicroFile+, a freely available software tool for the scientific community....
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For Immediate Release: Williston, VT (September 25, 2020)—To support the scientific community’s movement toward a more open and collaborative climate, MBF Bioscience is making their digital reconstruction file format, the Neuromorpholocial File Specification open and available to all researchers. MBF Bioscience has a long history of supporting openness and collaboration in neuroscience research. MBF Bioscience’s file format has evolved for over 30 years, influenced by leading neuroscientists,...
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Scientists at Western Sydney University used Stereo Investigator and Neurolucida 360 to quantify cells in a mouse model of neuroinflammation after feeding mice two different curcumin formulations. Some inflammation is normal in a healthy mammalian brain. But as the brain ages, processes can break down, leading to chronic neuroinflammation. This can develop into Alzheimer’s disease, dementia, and other neurodegenerative diseases. Scientists at Prof. Gerald Muench’s lab, at...
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MBF Bioscience was just awarded a patent by the USPTO for our new brain mapping technology! This novel technology is now available in our BrainMaker and NeuroInfo software to map image data and all associated measurements into a common coordinate system so that data can be compared across animals, cohorts, and laboratories. Learn more about NeuroInfo at https://www.mbfbioscience.com/neuroinfo ...
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