Vesalius is a versatile, cost-effective, confocal microscope system that is ideal for fast, large-scale, multi-channel 2D and 3D whole slide imaging of slide mounted specimens. Capture stunning images of thick or thin tissue samples, with customizable imaging options at speeds that are 10x faster than conventional laser scanning confocal microscopes and more than 100x faster than grid-based structured illumination. Benefit from high signal-to-noise ratio, minimal photobleaching, and eliminate out-of-focus planes, all while maximizing your productivity and budget with the fastest and most versatile confocal imaging system available.
The Vesalius system (developed in concert with CrestOptics) is the perfect tool for fast, multi-channel confocal image acquisition of large tissue specimens, including mouse, rat and non-human primate. Vesalius is easy to use and substantially reduces the time needed for image acquisitions compared to conventional confocal imaging systems, with no compromise in image quality.
Combine MBF Bioscience award-winning image analysis software, using the latest AI technology, with your Vesalius system to perform complex quantitative image analyses such as automated cell counting, neuron reconstruction and dendritic spine detection, as well as our gold-standard stereological analysis solutions.
You can include powerful analysis tools with your customized Vesalius system:
Vesalius can also be fully integrated with existing MBF Bioscience microscopy systems, including Stereo Investigator® and Neurolucida®. Acquire vast amounts of data from standard slides, expansion microscopy, or cleared tissue and analyze it with our software solutions that are developed for neuroscience research in collaboration with experts in the advanced-microscopy research community.
Acquisition speed over 1,000 fps on full Field of View (25mm)
Axial resolution (FWHM): ~600nm depending on objective lens
Image Depth: up to ~200um
FOV Field of view up to 25mm
Linear encoded motorized stage for the greatest accuracy and flexibility
Wide range of illumination sources (laser or LEDs, up to 7 excitation wavelengths from 390nm-750nm)
|Spinning disk geometry (diamater/spacing) |
The Vesalius enables a dynamic widefield/confocal transition and true Z optical sectioning in a single click.
Human iPS derived motoneurons
Neuron cell imaged at 100x
Human iPSC derived motoneurons. 60x oil
MBF’s utility is underscored by the number of references it receives in the worlds most important scientific publications.
Boeglin, M., E. Leyva-Díaz, et al.
Expression and function of C. elegans UNCP-18, a paralogue of the SM protein UNC-18View Publication
Rentsch, P., T. Egan, et al.
The ratio of M1 to M2 microglia in the striatum determines the severity of L-Dopa-induced dyskinesiasView Publication
Villar-Conde, S., V. Astillero-Lopez, et al.
Synaptic involvement of the human amygdala in Parkinson’s diseaseView Publication
Stimpson, C. D., J. B. Smaers, et al.
Evolutionary scaling and cognitive correlates of primate frontal cortex microstructureView Publication
MBF products are used across the globe by the most prestigious laboratories.
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"I am so happy to be a customer of your company. I always get great help related with your product or not. With the experienced members, you are the best team I've ever met. All of your staff are very kind and helpful. Thank you for your great help and support all the time."
"We’ve been very happy for many years with MBF products and the course of upgrades and improvements. Your service department is outstanding. I have gotten great help from the staff with the software and hardware."
"Our experience with the MBF equipment and especially the MBF people has been outstanding. I cannot speak any higher about their professionalism and attention for our needs."
"MBF provides excellent technical support and helps you to find the best technical tools for your research challenges on morphometry."
At MBF, we’ve spent decades understanding the needs of researchers and their labs — and have a suite of products and solutions that have been specifically designed for the needs of today’s most important and advanced labs. Our commitment to you is to spend time with you discussing the needs of your lab — so that we can make sure the solutions we provide for you are exactly what you’ll need. It’s part of our commitment to supporting you — before, during, and after you’ve made your decision. We look forward to talking with you!
Ground-breaking light sheet microscope system for cleared specimens.
A fast, and versatile whole slide scanner for quantitative analysis.
Neuron tracing & analysis directly at the microscope. The gold standard for neuron tracing.
The complete stereology solution. The gold standard for unbiased cell counting