Neurolucida^®360

Neurolucida 360: The leading image analysis software for automatic 3D neuron reconstruction and quantitative morphology

Neurolucida 360 is the most trusted software for comprehensive neuron reconstruction. Built by neuroscientists for neuroscientists, Neurolucida 360 is equipped with powerful automated algorithms for detection of neuronal structures present in 2D and 3D microscopy image data.

With built-in workflows, an intuitive user-interface, and interactive 3D environment, Neurolucida 360 makes it easy to reconstruct somas, axons, dendrites, varicosities, spines, and synapses.

Paired with the companion software, Neurolucida Explorer, you can quickly and effectively analyze the morphology of subcellular structures, whole cells, or complex connective networks – from any species.

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Delatour, L. C., Yeh, P. W., & Yeh, H. H. (2018). Ethanol Exposure In Utero Disrupts Radial Migration and Pyramidal Cell Development in the Somatosensory Cortex. Cerebral Cortex, bhy094-bhy094. doi: 10.1093/cercor/bhy094. http://dx.doi.org/10.1093/cercor/bhy094

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Erickson, R. P., Aras, S., Purandare, N., Hüttemann, M., Liu, J., Dragotto, J., . . . Grossman, L. I. (2020). Decreased membrane cholesterol in liver mitochondria of the point mutation mouse model of juvenile Niemann–Pick C1, Npc1nmf164. Mitochondrion, 51, 15-21. doi: https://doi.org/10.1016/j.mito.2019.12.003. http://www.sciencedirect.com/science/article/pii/S1567724919300017

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Fu, M.-m., McAlear, T. S., Nguyen, H., Oses-Prieto, J. A., Valenzuela, A., Shi, R. D., . . . Barres, B. A. (2019). The Golgi Outpost Protein TPPP Nucleates Microtubules and Is Critical for Myelination. Cell, 179(1), 132-146.e114. doi: https://doi.org/10.1016/j.cell.2019.08.025. http://www.sciencedirect.com/science/article/pii/S0092867419309134

Furuta, T., Bush, N. E., Yang, A. E.-T., Ebara, S., Miyazaki, N., Murata, K., . . . Hartmann, M. J. Z. (2020). The Cellular and Mechanical Basis for Response Characteristics of Identified Primary Afferents in the Rat Vibrissal System. Current Biology. doi: https://doi.org/10.1016/j.cub.2019.12.068. http://www.sciencedirect.com/science/article/pii/S0960982219317014

Gaborieau, E., Hurtado-Chong, A., Fernández, M., Azim, K., & Raineteau, O. (2018). A dual role for the transcription factor Sp8 in postnatal neurogenesis. Scientific Reports, 8(1), 14560. doi: 10.1038/s41598-018-32134-6. https://doi.org/10.1038/s41598-018-32134-6

Gennarino, V. A., Palmer, E. E., McDonell, L. M., Wang, L., Adamski, C. J., Koire, A., . . . Zoghbi, H. Y. (2018). A Mild PUM1 Mutation Is Associated with Adult-Onset Ataxia, whereas Haploinsufficiency Causes Developmental Delay and Seizures. Cell, 172(5), 924-936.e911. doi: https://doi.org/10.1016/j.cell.2018.02.006. http://www.sciencedirect.com/science/article/pii/S0092867418301508

Gisabella, B., Scammell, T., Bandaru, S. S., & Saper, C. B. (2019). Regulation of hippocampal dendritic spines following sleep deprivation. Journal of Comparative Neurology, 0(ja). doi: 10.1002/cne.24764. https://onlinelibrary.wiley.com/doi/abs/10.1002/cne.24764

Goodliffe, J. W., Song, H., Rubakovic, A., Chang, W., Medalla, M., Weaver, C. M., & Luebke, J. I. (2018). Differential changes to D1 and D2 medium spiny neurons in the 12-month-old Q175+/- mouse model of Huntington’s Disease. PLOS ONE, 13(8), e0200626. doi: 10.1371/journal.pone.0200626. https://doi.org/10.1371/journal.pone.0200626

Harley, S. B. R., Willis, E. F., Shaikh, S. N., Blackmore, D. G., Sah, P., Ruitenberg, M. J., . . . Vukovic, J. (2021). Selective ablation of BDNF from microglia reveals novel roles in self-renewal and hippocampal neurogenesis. The Journal of Neuroscience, JN-RM-2539-2520. doi: 10.1523/jneurosci.2539-20.2021. http://www.jneurosci.org/content/early/2021/03/22/JNEUROSCI.2539-20.2021...

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Helton, T. D., Zhao, M., Farris, S., & Dudek, S. M. (2018). Diversity of dendritic morphology and entorhinal cortex synaptic effectiveness in mouse CA2 pyramidal neurons. Hippocampus, 0(ja). doi: doi:10.1002/hipo.23012. https://onlinelibrary.wiley.com/doi/abs/10.1002/hipo.23012

Henderson, B. W., Greathouse, K. M., Ramdas, R., Walker, C. K., Rao, T. C., Bach, S. V., . . . Herskowitz, J. H. (2019). Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against β-amyloid. Science Signaling, 12(587), eaaw9318. doi. https://stke.sciencemag.org/content/12/587/eaaw9318.abstract

Hinova-Palova, D., Kotov, G., Landzhov, B., Edelstein, L., Iliev, A., Stanchev, S., . . . Paloff, A. (2019). Cytoarchitecture of the dorsal claustrum of the cat: a quantitative Golgi study. [journal article]. Journal of Molecular Histology. doi: 10.1007/s10735-019-09839-7. https://doi.org/10.1007/s10735-019-09839-7

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Hoshiba, Y., Toda, T., Ebisu, H., Wakimoto, M., Yanagi, S., & Kawasaki, H. (2016). Sox11 Balances Dendritic Morphogenesis with Neuronal Migration in the Developing Cerebral Cortex. The Journal of Neuroscience, 36(21), 5775-5784. doi. 

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