MBF Bioscience Blog

    A monkey spots a mango and part of its brain lights up. The action takes place in the inferior temporal cortex, part of the brain that's essential to object recognition. Using retrograde tracing and anatomical imaging, scientists at the National Institute of Neuroscience, and the RIKEN Brain Science Institute in Japan identified two interwoven, yet distinct, systems within the region's complex circuitry.   “Our anatomical findings provide evidence...

Read More

  WormLab is already contributing to a variety of research projects from the study of neurodegeneration at Johns Hopkins, to research on neural circuit function at UMass, neurotransmitter transporters at Vanderbilt University, and explorations into how the brain controls growth and fat metabolism at the University of Nevada, Reno. Why? WormLab is intuitive, fast, and yields an astounding amount of data very quickly.   Try it with your...

Read More

Revving engines, blasting sirens, the drummer next door. Despite the myriad sensory stimuli going on around us at any given moment, humans have the ability to stay focused on the task at hand. This skill is due to a part of the brain known as the neocortex, a six-layer structure whose intricate wiring is largely a mystery. But researchers at the University of Virginia just...

Read More

  Humans invent tools, talk to each other, and philosophize, thanks to a part of the brain known as the neocortex. All mammals have it, allowing them to function on a more sophisticated level than animals like geckos and sea anemones. And then there are birds. Avians don't have a neocortex, yet they display higher level processes in their behavior, a characteristic which led Dr. Harvey...

Read More

  [caption id="attachment_3412" align="aligncenter" width="238"] Original figures published with permission from Dr. Ed Glaser[/caption]   In 1963, Dr. Ed Glaser (co-founder of MBF Bioscience) and Dr. Hendrik van der Loos were at the John Hopkins Medical School putting the final touches on the first computer microscope, an analog computer connected to a light microscope. It was described as a system for attaching X-Y-Z transducers to a microscope stage,...

Read More

Imagine if you could switch your depression off like a light. Researchers did it in mice. They used optogenetics to gain more insight into how brain circuits work in cases of depression, and discovered that different types of stress trigger different activity patterns in the same brain circuit.   Two papers published recently in the journal Nature describe how neuronal activity in specific brain circuits in mice...

Read More

    At first, all appears normal with the infant's development. But one day, around her first birthday, she stops making eye contact, her babbling comes to an end, she wrings her hands, and holds her breath. The child will likely survive into adulthood, but with Rett syndrome, she will lead a life with severe disabilities.   The symptoms of this autism-related disorder are complex, and treatments are not...

Read More

A 3D model of a mouse diaphragm appears on the monitor. Blood vessels branch out from entry points around the muscle's periphery, engaging in a graceful choreography with the nerve fibers that radiate from its center.   Could these two networks work together to ensure healthy blood and oxygen flow to the muscle? Or do they exist independently of each other, house mates living side by side...

Read More

Thirty-six high school students passionate about neuroscience will be competing at the 4th annual Vermont Brain Bee on February 9th, 2013 at the University of Vermont College of Medicine. Participants will be asked questions about a wide variety of topics: anatomy and development, learning and memory, stress, types of research, neurogenerative disorders, etc. They will also get the opportunity to engage in neuroscience activities and...

Read More

  If a head gets hit hard enough, the trauma occurs instantly. Neurons die, the brain swells as microglia cells rush to the damaged area, and the protective armor known as the blood brain barrier might even rupture. But it doesn't end there. Long term effects include cognitive impairment, loss of sensory processing, and susceptibility to neurodegenerative diseases like Alzheimer's.   Researchers at the University of South Florida say...

Read More