The Rapid Multi Region (RMR) scanner increases your microscope’s imaging rate by subdividing the field of view into multiple regions of interest. Its novel design combines the flexibility of two galvos and the speed of a resonant scanner into an integrated, compact device. The scanner is fully compatible with ScanImage®‘s powerful scanning modes. The flexible mounting options allow straightforward installation on a number of commercial 2P microscopes, including the Thorlabs BScope and Sutter MOM, as well as DIY microscopes.
The RMR is a resonant-galvo galvo module for 2P microscopes. It was developed as a novel solution for neuroscientists seeking to scan multiple regions of interest with high time resolution.
The RMR is superior to typical resonant-galvo configurations, in which if you have several small regions-of-interest (ROIs) within a larger field-of-view, you could scan the full field of view and then only analyze the ROIs you are interested in. However, you pay a price in frame rate because you’re spending a lot of time raster scanning areas that you’re not interested in.
The additional galvo in the RMR allows you to raster scan a small region and then move that around in X and Y.
Integrated resonant and 2x galvo mirrors
Compatible with Thorlabs Bscope II, Sutter MOM, and DIY microscopes
2x Cambridge galvo 6215H mirrors
Cambridge resonant mirror 8kHz
Group delay dispersion < 1000fs^2
FOV: 20 degree optical
Suitable for a laser beam diameter up to 4mm
30mm cage mountable
Controller box included
|Input Voltage Nominal||100-120||V (AC)|
|Input Voltage Range||90-132||V (AC)|
|Input Voltage Frequency||50-60||Hz|
|Power Consumption (maximum)||1050||W|
|Input Beam Diameter||< 4||mm|
|Group Dispersion Delay||< 1000||fs2|
|Maximum Galvo Line Rate at Full Amplitude||< 1000||Hz|
|Resonant Scanner Frequency (Nominal)||8000||Hz|
|Galvo Scan Angle||+-10||degrees (optical)|
|Resonant Scan Angle||+-13||degrees (optical)|
|Usable Resonant Scan Angle Before Clipping Occurs||+-10||degrees (optical)|
|Weight Scan Head||1.5||kg|
|Dimensions Scan Head||
|Dimensions Controller Box||483 x 364 x 89||mm|
|Maximum Noise Level at 1m distance Lpl(20 µPa)||45||dB(A)|
Lu, J., Behbahani, A.H., Hamburg, L. et al. Transforming representations of movement from body- to world-centric space. Nature 601, 98–104 (2022). https://doi.org/10.1038/s41586-021-04191-x
Download our product sheet here.
RMR scanner is used across the globe by the most prestigious laboratories.
MBF’s software utility is underscored by the number of references it receives in the worlds most important scientific publications. See examples below:
Lu, J., Behbahani, A.H., Hamburg, L. et al.
"Transforming representations of movement from body- to world-centric space."
Pettit, N. L., X. C. Yuan, et al.
"Hippocampal place codes are gated by behavioral engagement." Nature Neuroscience.View Publication
Weber-Adrian, D., R. H. Kofoed, et al.
"Systemic AAV6-synapsin-GFP administration results in lower liver biodistribution, compared to AAV1&2 and AAV9, with neuronal expression following ultrasound-mediated brain delivery." Scientific Reports 11(1): 1934.View Publication
Sterling, J. K., T.-I. Kam, et al.
"Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein." Cell Reports 38(7): 110358.View Publication
Tanaka, S., K. Takizawa, et al.
"One-step visualization of natural cell activities in non-labeled living spheroids." Scientific Reports 12(1): 1500.View Publication
Alkondon, M., Pereira, E. F. R., Eisenberg, H. M., & Albuquerque, E. X.
Nicotinic Receptor Activation in Human Cerebral Cortical Interneurons: a Mechanism for Inhibition and Disinhibition of Neuronal Networks. Journal of Neuroscience, 20(1), 66-75.View Publication
Leung, C., S. Robbins, et al. (2021).
"3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system." iScience 24(7): 102795.View Publication
Kim, S.-H., S. H. Hadley, et al.
"Mapping of Sensory Nerve Subsets within the Vagal Ganglia and the Brainstem Using Reporter Mice for Pirt, TRPV1, 5-HT3, and Tac1 Expression." eNeuro 7(2): ENEURO.0494-0419.2020.View Publication
Yes. It is not required to drive the resonant scanners all the time. You can use it only for experiments where it is needed and leave it disabled for others.
No. The RMR scanner can be operated by any system that can generate the appropriate control signals.
We can custom-build an RMR scanner with a 12kHz resonant scanner. Please contact to discuss this option.
The RMR has flexible mounting options allows installation on a Thorlabs BScope, a Sutter MOM and DIY microscopes.
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"MBF provides excellent technical support and helps you to find the best technical tools for your research challenges on morphometry."
At MBF, we’ve spent decades understanding the needs of researchers and their labs — and have a suite of products and solutions that have been specifically designed for the needs of today’s most important and advanced labs. Our commitment to you is to spend time with you discussing the needs of your lab — so that we can make sure the solutions we provide for you are exactly what you’ll need. It’s part of our commitment to supporting you — before, during, and after you’ve made your decision. We look forward to talking with you!