The Rapid Multi Region (RMR) scanner increases your microscope’s imaging rate by subdividing the field of view into multiple regions of interest. Its novel design combines the flexibility of two galvos and the speed of a resonant scanner into an integrated, compact device. The scanner is fully compatible with ScanImage‘s powerful scanning modes. The flexible mounting options allow straightforward installation on a number of commercial 2P microscopes, including the Thorlabs BScope and Sutter MOM, as well as DIY microscopes.
The RMR is a resonant-galvo galvo module for 2P microscopes. It was developed as a novel solution for neuroscientists seeking to scan multiple regions of interest with high time resolution.
The RMR is superior to typical resonant-galvo configurations, in which if you have several small regions-of-interest (ROIs) within a larger field-of-view, you could scan the full field of view and then only analyze the ROIs you are interested in. However, you pay a price in frame rate because you’re spending a lot of time raster scanning areas that you’re not interested in.
The additional galvo in the RMR allows you to raster scan a small region and then move that around in X and Y.
Integrated resonant and 2x galvo mirrors
Compatible with Thorlabs Bscope II, Sutter MOM, and DIY microscopes
2x Cambridge galvo 6215H mirrors
Cambridge resonant mirror 8kHz
Group delay dispersion < 1000fs^2
FOV: 20 degree optical
Suitable for a laser beam diameter up to 4mm
30mm cage mountable
Controller box included
|Input Voltage Nominal||100-120||V (AC)|
|Input Voltage Range||90-132||V (AC)|
|Input Voltage Frequency||50-60||Hz|
|Power Consumption (maximum)||1050||W|
|Input Beam Diameter||< 4||mm|
|Group Dispersion Delay||< 1000||fs2|
|Maximum Galvo Line Rate at Full Amplitude||< 1000||Hz|
|Resonant Scanner Frequency (Nominal)||8000||Hz|
|Galvo Scan Angle||+-10||degrees (optical)|
|Resonant Scan Angle||+-13||degrees (optical)|
|Usable Resonant Scan Angle Before Clipping Occurs||+-10||degrees (optical)|
|Weight Scan Head||1.5||kg|
|Dimensions Scan Head||
|Dimensions Controller Box||483 x 364 x 89||mm|
|Maximum Noise Level at 1m distance Lpl(20 µPa)||45||dB(A)|
Lu, J., Behbahani, A.H., Hamburg, L. et al. Transforming representations of movement from body- to world-centric space. Nature 601, 98–104 (2022). https://doi.org/10.1038/s41586-021-04191-x
Download Rapid Multi Region Scanner product sheet here.
RMR scanner is used across the globe by the most prestigious laboratories.
MBF’s software utility is underscored by the number of references it receives in the worlds most important scientific publications. See examples below:
Teixeira, L. L., H. M. Alencar, et al.
Oral Treatment with the Extract of Euterpe oleracea Mart. Improves Motor Dysfunction and Reduces Brain Injury in Rats Subjected to Ischemic StrokeView Publication
Pickett, L. A., J. W. VanRyzin, et al.
“Microglia phagocytosis mediates the volume and function of the rat sexually dimorphic nucleus of the preoptic area.”View Publication
Ferrer Ortas, J., P. Mahou, et al.
“Label-free imaging of red blood cells and oxygenation with color third-order sum-frequency generation microscopy.” Light: Science & ApplicationsView Publication
Zhao, K., Y. Zhang, et al.
“The joint effects of nanoplastics and TBBPA on neurodevelopmental toxicity in Caenorhabditis elegans.” Toxicology ResearchView Publication
Lu, J., Behbahani, A.H., Hamburg, L. et al.
"Transforming representations of movement from body- to world-centric space."
Paletzki, R. and C. R. Gerfen
“Whole Mouse Brain Image Reconstruction from Serial Coronal Sections Using FIJI (ImageJ).”View Publication
Leung, C., S. Robbins, et al. (2021).
"3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system." iScience 24(7): 102795.View Publication
Kim, S.-H., S. H. Hadley, et al.
"Mapping of Sensory Nerve Subsets within the Vagal Ganglia and the Brainstem Using Reporter Mice for Pirt, TRPV1, 5-HT3, and Tac1 Expression." eNeuro 7(2): ENEURO.0494-0419.2020.View Publication
Yes. It is not required to drive the resonant scanners all the time. You can use it only for experiments where it is needed and leave it disabled for others.
No. The RMR scanner can be operated by any system that can generate the appropriate control signals.
We can custom-build an RMR scanner with a 12kHz resonant scanner. Please contact to discuss this option.
The RMR has flexible mounting options allows installation on a Thorlabs BScope, a Sutter MOM and DIY microscopes.
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