Cleared Tissue and Whole Organ Research

MBF Bioscience >  Blog > Scientific Applications & Use Cases  > Cleared Tissue and Whole Organ Research

The Image Volume Fractionator probe, available in Stereo Investigator - Cleared Tissue Edition, is facilitating huge efficiency gains for quantifying the number of cells.   At Dr. Patrick R. Hof’s lab at the Icahn School of Medicine at Mount Sinai, researchers imaged the cerebral cortex using light-sheet fluorescence microscopy and quantified the number of neurons, including those that express proteins involved in Alzheimer’s disease and schizophrenia, using...

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For Immediate Release  Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D.     The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...

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This is an image of a full Light Sheet Microscope called ClearScope

For Immediate Release: Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard for microscopic imaging.   The new decade is poised to bring about incredible scientific innovations, and MBF Bioscience is leading the charge in 2020 with the creation of the “light sheet theta microscope” system, ClearScope.   MBF Bioscience secured exclusive license from Columbia University to develop the light...

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  The importance of studying the brain in three dimentions is something we understand at MBF Bioscience. Every day scientists around the world use our products to reconstruct neurons and analyze brain cells in 3D. That's why we're excited to hear about the new possibilities for whole brain analysis coming out of Dr. Karl Deisseroth's lab at Stanford University.   A press release issued last week describes a...

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