MBF Bioscience Blog

Scientists at Western Sydney University used Stereo Investigator and Neurolucida 360 to quantify cells in a mouse model of neuroinflammation after feeding mice two different curcumin formulations. Some inflammation is normal in a healthy mammalian brain. But as the brain ages, processes can break down, leading to chronic neuroinflammation. This can develop into Alzheimer’s disease, dementia, and other neurodegenerative diseases.   Scientists at Prof. Gerald Muench’s lab, at...

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MBF Bioscience was just awarded a patent by the USPTO for our new brain mapping technology! This novel technology is now available in our BrainMaker and NeuroInfo software to map image data and all associated measurements into a common coordinate system so that data can be compared across animals, cohorts, and laboratories. Learn more about NeuroInfo at https://www.mbfbioscience.com/neuroinfo    ...

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Researchers Quantify Improvement in Heart Vasculature with Vesselucida 360 and Vesselucida Explorer Cells need oxygen to survive, but during a heart attack, blood flow is restricted and cardiac cells can’t get the oxygen they need to stay alive. A new therapy, developed by researchers at the Coulombe Lab at Brown University may be able to provide the heart with the support it needs to recover after...

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Biolucida for Medical Education is a learning platform that serves high resolution microscope slides to students without the need for a physical microscope.   As universities around the world move to online classes during the COVID-19 pandemic, educators suddenly need to find ways to create authentic learning experiences for their students. Biolucida for Medical Education creates that experience by giving students studying at home the same experience...

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An interdisciplinary team of researchers, including MBF Bioscience’s Dr. Susan Tappan and Maci Heal, have created a fully reconstructed, virtual 3D heart, digitally showcasing the heart's unique network of neurons for the first time. The investigators in this study--appearing May 26 in the journal iScience--created a comprehensive map of the intrinsic cardiac nervous system at a cellular scale using MBF Bioscience’s Tissue Mapper and TissueMaker software....

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Neurolucida 360 Used to Analyze Dendrites and Dendritic Spines Amyloid plaques and tau tangles are the hallmarks of Alzheimer’s disease (AD) pathology, but synapse loss is what causes cognitive decline, scientists say. In a paper published in Science Signaling, researchers at the Herskowitz Lab, at the University of Alabama at Birmingham, used Neurolucida 360 to analyze spine density and dendritic length in hAPP mice — a...

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This is an image of a full Light Sheet Microscope called ClearScope

For Immediate Release: Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard for microscopic imaging.   The new decade is poised to bring about incredible scientific innovations, and MBF Bioscience is leading the charge in 2020 with the creation of the “light sheet theta microscope” system, ClearScope.   MBF Bioscience secured exclusive license from Columbia University to develop the light...

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New Software Application Quantifies Changes in Dendritic Spine Morphology Over Time   Williston, VT — December 10, 2019 — The ability to track the changes that occur in dendritic spine morphology over time is critical to many scientific studies, which is why MBF Bioscience is pleased to announce the launch of MicroDynamix. This powerful new software application helps neuroscientists acquire more information about morphological changes in the...

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Scientists use NeuroInfo to help navigate the brain and compare findings across labs   Reproducibility has always been a primary goal in science. But the human effort involved in replicating a research study and analyzing the results, can be considerable. NeuroInfo®is a revolutionary new tool that scientists are using to register whole slide images into a standardized mouse brain atlas in an easy, automated way. Images...

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Dr. Edmund Glaser devoted his career of more than four decades to the field of neuroscience. Most notably, in 1963, he co-invented computer microscopy, a pioneering method of quantifying the brain’s morphometry. This technology, for the first time, applied computer techniques to the neuroanatomical world, permitting scientists to precisely quantify the brain’s three-dimensional structure. It simplified time-consuming, inexact classical methodologies in an efficient and cost-effective...

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