Researchers cited MBF Bioscience systems in 10 papers between 4/13/2018 and 4/20/2018

Stereo Investigator:

Cordaro, M., Siracusa, R., Crupi, R., Impellizzeri, D., Peritore, A. F., D’Amico, R., . . . Cuzzocrea, S. (2018). 2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease. Molecular Neurobiology. doi: 10.1007/s12035-018-1064-2.

Heilbronner, S. R., Meyer, M. A. A., Choi, E. Y., & Haber, S. N. (2018). How do cortico-striatal projections impact on downstream pallidal circuitry?  Brain Structure and Function. doi: 10.1007/s00429-018-1662-9.

Miguel-Hidalgo, J., Moulana, M., Deloach, P., & Rajkowska, G. (2018). F103. Reduced Extent of Myelin Basic Protein Immunoreactivity in Rat Prelimbic and Orbitofrontal Cortices After Chronic Unpredictable Stress and its Correlation With Connexin 43 and Connexin 30. Biological Psychiatry, 83(9), S277-S278. doi: 10.1016/j.biopsych.2018.02.716.

Misheneva, V., McFarland, R., Jouroukhin, Y., Severance, E., Yolken, R., & Pletnikov, M. (2018). F101. Animal Models of Mood Disorders and the Evaluation of Probiotics. Biological Psychiatry, 83(9), S276-S277. doi: 10.1016/j.biopsych.2018.02.714.

Walters, K. A., Edwards, M. C., Tesic, D., Caldwell, A. S., Jimenez, M., Smith, J. T., & Handelsman, D. J. (2018). The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis. Neuroendocrinology. doi: https://doi.org/10.1159/000487762 Continue reading “Researchers cited MBF Bioscience systems in 10 papers between 4/13/2018 and 4/20/2018” »

Researchers cited MBF Bioscience systems in 16 papers between 4/6/2018 and 4/13/2018

Stereo Investigator: 

Chen, C., Li, X., Ge, G., Liu, J., Biju, K. C., Laing, S. D., . . . Li, S. (2018). GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice. Scientific Reports, 8(1), 5460. doi: 10.1038/s41598-018-23795-4.

Demars, F., Clark, K., Wyeth, M. S., Abrams, E., & Buckmaster, P. S. (2018). A single subconvulsant dose of domoic acid at mid-gestation does not cause temporal lobe epilepsy in mice. Neurotoxicology. doi: https://doi.org/10.1016/j.neuro.2018.04.001.

Garrett, L., Ung, M. C., Heermann, T., Niedermeier, K. M., & Hölter, S. (2018). Analysis of Neuropsychiatric Disease‐Related Functional Neuroanatomical Markers in Mice. Current Protocols in Mouse Biology, 8(1), 79-128. doi:10.1002/cpmo.37.

Piontkewitz, Y., Arad, M., & Weiner, I. (2018). T194. BRAIN STRUCTURAL AND BEHAVIORAL ABNORMALITIES FOLLOWING PRENATAL EXPOSURE TO MATERNAL INFLAMMATION ARE PREVENTED BY EARLY BUT NOT LATE INTERVENTION. Schizophrenia Bulletin, 44(suppl_1), S191-S192. doi: 10.1093/schbul/sby016.470.  Continue reading “Researchers cited MBF Bioscience systems in 16 papers between 4/6/2018 and 4/13/2018” »

Researchers cited MBF Bioscience systems in 27 papers between 3/23/2018 and 4/6/2018

Stereo Investigator: 
Crupi, R., Impellizzeri, D., Cordaro, M., Siracusa, R., Casili, G., Evangelista, M., & Cuzzocrea, S. (2018). N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.  Molecular Neurobiology. doi: 10.1007/s12035-018-0959-2.

Dingle, A. M., Yap, K. K., Gerrand, Y.-W., Taylor, C. J., Keramidaris, E., Lokmic, Z., . . . Mitchell, G. M. (2018). Characterization of isolated liver sinusoidal endothelial cells for liver bioengineering. Angiogenesis. doi: 10.1007/s10456-018-9610-0.

Duthie, M. S., Pena, M. T., Ebenezer, G. J., Gillis, T. P., Sharma, R., Cunningham, K., . . . Reed, S. G. (2018). LepVax, a defined subunit vaccine that provides effective pre-exposure and post-exposure prophylaxis of M. leprae infection. npj Vaccines, 3(1), 12. doi: 10.1038/s41541-018-0050-z.

Dutta, R. R., Taffe, M. A., & Mandyam, C. D. (2018). Chronic administration of amphetamines disturbs development of neural progenitor cells in young adult nonhuman primates. Progress in Neuro-Psychopharmacology and Biological Psychiatry. doi: https://doi.org/10.1016/j.pnpbp.2018.03.023.

Hormigo, S., López, D. E., Cardoso, A., Zapata, G., Sepúlveda, J., & Castellano, O. (2018). Direct and indirect nigrofugal projections to the nucleus reticularis pontis caudalis mediate in the motor execution of the acoustic startle reflex. Brain Structure and Function. doi: 10.1007/s00429-018-1654-9.

Continue reading “Researchers cited MBF Bioscience systems in 27 papers between 3/23/2018 and 4/6/2018” »

Researchers cited MBF Bioscience systems in 13 papers between 3/16/2018 and 3/23/2018

Stereo Investigator:
journal images sm

Cisbani, G., Le Behot, A., Plante, M.-M., Préfontaine, P., Lecordier, M., & Rivest, S. (2018). Role of the chemokine receptors CCR2 and CX3CR1 in an experimental model of thrombotic stroke. Brain, Behavior, and Immunity. doi: https://doi.org/10.1016/j.bbi.2018.03.008.

Du, R.-H., Sun, H.-B., Hu, Z.-L., Lu, M., Ding, J.-H., & Hu, G. (2018). Kir6.1/K-ATP channel modulates microglia phenotypes: implication in Parkinson’s disease. Cell death & disease, 9(3), 404. doi: 10.1038/s41419-018-0437-9.

McGowan, S. E., & McCoy, D. M. (2018). Neuropilin-1and platelet-derived growth factor receptors cooperatively regulate intermediate filaments and mesenchymal cell migration during alveolar septation. American Journal of Physiology-Lung Cellular and Molecular Physiology.

Nagahara, A. H., Wilson, B. R., Ivasyk, I., Kovacs, I., Rawalji, S., Bringas, J. R., . . . Bankiewicz, K. S. (2018). MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates. Gene Therapy, 1.

Neurolucida:

Brudvig, J. J., Cain, J. T., Schmidt-Grimminger, G. G., Stumpo, D. J., Roux, K. J., Blackshear, P. J., & Weimer, J. M. (2018). MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation.  Molecular Neurobiology. doi: 10.1007/s12035-018-0990-3.

Carr, H., Alexander, T. C., Groves, T., Kiffer, F., Wang, J., Price, E., . . . Allen, A. R. (2018). Early effects of 16O radiation on Neuronal Morphology and Cognition in a Murine Model. Life Sciences in Space Research. doi: https://doi.org/10.1016/j.lssr.2018.03.001Continue reading “Researchers cited MBF Bioscience systems in 13 papers between 3/16/2018 and 3/23/2018” »

Researchers cited MBF Bioscience systems in 11 papers between 3/9/2018 and 3/16/2018

Stereo Investigator:
journal images sm

Deroche-Gamonet, V., Revest, J.-M., Fiancette, J.-F., Balado, E., Koehl, M., Grosjean, N., . . . Piazza, P.-V. (2018). Depleting adult dentate gyrus neurogenesis increases cocaine-seeking behavior. Molecular Psychiatry. doi: 10.1038/s41380-018-0038-0.

Mendez-Gomez, H. R., Singh, J., Meyers, C., Chen, W., Gorbatyuk, O. S., & Muzyczka, N. (2018). The Lipase Activity of Phospholipase D2 is Responsible for Nigral Neurodegeneration in a Rat Model of Parkinson’s Disease. Neuroscience. doi: https://doi.org/10.1016/j.neuroscience.2018.02.047.

Wang, Y., Wang, Y., Liu, J., & Wang, X. (2018). Electroacupuncture Alleviates Motor Symptoms and Up-Regulates Vesicular Glutamatergic Transporter 1 Expression in the Subthalamic Nucleus in a Unilateral 6-Hydroxydopamine-Lesioned Hemi-Parkinsonian Rat Model.  Neuroscience bulletin. doi: 10.1007/s12264-018-0213-y.

Neurolucida:

Borreca, A., Latina, V., Corsetti, V., Middei, S., Piccinin, S., Della Valle, F., . . . Amadoro, G. (2018). AD-Related N-Terminal Truncated Tau Is Sufficient to Recapitulate In Vivo the Early Perturbations of Human Neuropathology: Implications for Immunotherapy. Molecular Neurobiology. doi: 10.1007/s12035-018-0974-3.

Continue reading “Researchers cited MBF Bioscience systems in 11 papers between 3/9/2018 and 3/16/2018” »

Researchers cited MBF Bioscience systems in 28 papers between 3/2/2018 and 3/9/2018

Stereo Investigator:
journal images sm

Akca, G., Eren, H., Tumkaya, L., Mercantepe, T., Horsanali, M. O., Deveci, E., . . . Yilmaz, A. (2018). The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats. Biomedicine and Pharmacotherapy, 100, 575-582. doi: https://doi.org/10.1016/j.biopha.2018.02.042.

Aytan, N., Choi, J.-K., Carreras, I., Crabtree, L., Nguyen, B., Lehar, M., . . . Dedeoglu, A. Protective effects of 7,8-dihydroxyflavone on neuropathological and neurochemical changes in a mouse model of Alzheimer’s disease. European Journal of Pharmacology. doi: https://doi.org/10.1016/j.ejphar.2018.02.045.

Chu, X., Zhou, S., Sun, R., Wang, L., Xing, C., Liang, R., & Kong, Q. (2018). Chrysophanol Relieves Cognition Deficits and Neuronal Loss Through Inhibition of Inflammation in Diabetic Mice. Neurochemical Research. doi: 10.1007/s11064-018-2503-1. https://doi.org/10.1007/s11064-018-2503-1

Domínguez-Álvaro, M., Montero-Crespo, M., Blazquez-Llorca, L., Insausti, R., DeFelipe, J., & Alonso-Nanclares, L. (2018). Three-dimensional analysis of synapses in the transentorhinal cortex of Alzheimer’s disease patients. Acta Neuropathologica Communications, 6(1), 20. doi: 10.1186/s40478-018-0520-6.

El Massri, N., Weinrich, T. W., Kam, J. H., Jeffery, G., & Mitrofanis, J. (2018). Photobiomodulation reduces gliosis in the basal ganglia of aged mice. Neurobiology of Aging. doi: https://doi.org/10.1016/j.neurobiolaging.2018.02.019.

Continue reading “Researchers cited MBF Bioscience systems in 28 papers between 3/2/2018 and 3/9/2018” »

Researchers cited MBF Bioscience systems in 15 papers between 12/8/2017 and 12/15/2017

Stereo Investigator:
journal images sm

Garcia-Miralles, M., Geva, M., Tan, J. Y., Yusof, N. A. B. M., Cha, Y., Kusko, R., . . . Pouladi, M. A. (2017). Early pridopidine treatment improves behavioral and transcriptional deficits in YAC128 Huntington disease mice. JCI Insight, 2(23). doi: 10.1172/jci.insight.95665.

Gomez-Smith, M., Janik, R., Lake, E. M., Thomason, L. A. M., Adams, C., Jeffers, M. S., . . . Corbett, D. (2017). Reduced Cerebrovascular Reactivity and Increased Resting Cerebral Perfusion in Rats Exposed to a Cafeteria Diet. Neuroscience. doi: https://doi.org/10.1016/j.neuroscience.2017.11.054.

Hawkins, R. F. W., Patenaude, A., Dumas, A., Jain, R., Tesfagiorgis, Y., Kerfoot, S., . . . Vallières, L. (2017). ICAM1+ neutrophils promote chronic inflammation via ASPRV1 in B cell–dependent autoimmune encephalomyelitis. JCI Insight, 2(23). doi: 10.1172/jci.insight.96882.

Joseph, M., Anglada-Huguet, M., Paesler, K., Mandelkow, E., & Mandelkow, E.-M. (2017). Anti-aggregant tau mutant promotes neurogenesis. Molecular Neurodegeneration, 12(1), 88. doi: 10.1186/s13024-017-0230-8.

Kelm-Nelson, C. A., Brauer, A. F. L., Barth, K. J., Lake, J. M., Sinnen, M. L. K., Stehula, F. J., . . . Ciucci, M. R. (2018). Characterization of early-onset motor deficits in the Pink1−/− mouse model of Parkinson disease. Brain Research, 1680, 1-12. doi: https://doi.org/10.1016/j.brainres.2017.12.002.

Continue reading “Researchers cited MBF Bioscience systems in 15 papers between 12/8/2017 and 12/15/2017” »

Diet Restriction Slows Neurodegeneration and Extends Lifespan of DNA-Repair-Deficient Mice

DNA damage occurs in human cells at a constant rate. These cells are usually able to repair themselves, but sometimes deficiencies in certain genes cause the repair process to shut down. When damaged DNA isn’t fixed, mutations can occur that cause accelerated aging or cancerous tumors to form (Hoeijmakers, 2009). Scientists at Erasmus University Medical Center in Rotterdam have found a way to slow down the process – at least in mice.

In a study published in Nature, the researchers report that when mice deficient in the DNA-repair genes Ercc1 or Xpg are put on a restricted diet, they experience better overall health and increased lifespans compared to DNA-repair-deficient mice fed a normal diet. They also found significantly lower levels of neurodegeneration in the brains and spinal cords of diet restricted animals compared to controls.

“Here we report that a dietary restriction of 30 percent tripled the median and maximal remaining lifespans of these progeroid mice, strongly retarding numerous aspects of accelerated aging Mice undergoing dietary restriction retained 50 percent more neurons and maintained full motor function far beyond the lifespan of mice fed ad libitum,” (Vermeij, et al 2016).

Since the DNA-repair-deficient mice were already smaller and weaker than normal mice, the Rotterdam researchers wondered whether diet restriction would be beneficial or detrimental to their health. They found that gradually restricting the diets of DNA-repair-deficient mice starting at age seven weeks increased their median lifespans from 10 to 35 weeks in males and 13 to 39 weeks in females as compared to controls.

They also saw significant differences in the levels of neurodegeneration between these two populations. Using Stereo Investigator, they found 50 percent more neurons in the brains of diet-restricted mice compared to those fed a normal diet. They also saw lower levels of cells expressing p53 – a protein expressed in response to DNA damage – in diet-restricted mice.

According to the authors, dietary restriction may not fix defects in DNA repair mechanisms, but it may help to reduce the severity and speed at which the damage occurs.

“Our findings establish the Ercc1 mouse as a powerful model organism for health-sustaining interventions, reveal potential for reducing endogenous DNA damage, facilitate a better understanding of the molecular mechanism of dietary restriction and suggest a role for counterintuitive dietary-restriction-like therapy for human progeroid genome instability syndromes and possibly neurodegeneration in general,” (Vermeij, et al 2016).

Vermeij W.P., Dollé M.E.T., Reiling E., Jaarsma D., Payan-Gomez C, Bombardieri C.R., Wu H., Roks A.J.M., Botter S.M., van der Eerden B.C., Youssef S.A., Kuiper R.V., Nagarajah B., van Oostrom C.T., Brandt R.M.C., Barnhoorn S., Imholz S., Pennings J.L.A., de Bruin A., Gyenis Á., Pothof J, Vijg J, van Steeg H., and Hoeijmakers J.H.J. (2016) Restricted diet delays accelerated aging and genomic stress in DNA repair deficient mice. Nature 537, 427-431, doi:10.1038/nature19329

Hoeijmakers JH (2009) DNA Damage, aging, and cancer. N Engl J Med; 361:1475-1485, DOI: 10.1056/NEJMra0804615

Stock image of DNA used in accordance with the CC0 public domain license.

Researchers cited MBF Bioscience systems in 30 papers between 09/01/2017 and 09/22/2017

Stereo Investigator:journal images sm

Bebber, M. R. (2017). Tempered strength: A controlled experiment assessing opportunity costs of adding temper to clay. Journal of Archaeological Science, 86, 1-13. doi: http://dx.doi.org/10.1016/j.jas.2017.08.002.

de Ávila, C., Chometton, S., Lenglos, C., Calvez, J., Gundlach, A. L., & Timofeeva, E. (2017). Differential effects of relaxin-3 and a selective relaxin-3 receptor agonist on food and water intake and hypothalamic neuronal activity in rats. Behavioural Brain Research. doi: http://dx.doi.org/10.1016/j.bbr.2017.08.044.

El-Feky, G. S., El-Banna, S. T., El-Bahy, G. S., Abdelrazek, E. M., & Kamal, M. (2017). Alginate coated chitosan nanogel for the controlled topical delivery of Silver sulfadiazine. Carbohydrate Polymers. doi: http://dx.doi.org/10.1016/j.carbpol.2017.08.104.

Chikama, K., Yamada, H., Tsukamoto, T., Kajitani, K., Nakabeppu, Y., & Uchimura, N. (2017). Chronic atypical antipsychotics, but not haloperidol, increase neurogenesis in the hippocampus of adult mouse. Brain Research, 1676(Supplement C), 77-82. doi: https://doi.org/10.1016/j.brainres.2017.09.006.

Ghuman, H., Gerwig, M., Nicholls, F. J., Liu, J. R., Donnelly, J., Badylak, S. F., & Modo, M. (2017). Long-term retention of ECM hydrogel after implantation into a sub-acute stroke cavity reduces lesion volume. Acta Biomaterialia. doi: https://doi.org/10.1016/j.actbio.2017.09.011.

Hawlitschka, A., Holzmann, C., Witt, S., Spiewok, J., Neumann, A.-M., Schmitt, O., . . . Antipova, V. (2017). Intrastriatally injected botulinum neurotoxin-A differently effects cholinergic and dopaminergic fibers in C57BL/6 mice. Brain Research, 1676(Supplement C), 46-56. doi: https://doi.org/10.1016/j.brainres.2017.09.016.

Continue reading “Researchers cited MBF Bioscience systems in 30 papers between 09/01/2017 and 09/22/2017” »

Researchers cited MBF Bioscience systems in 27 papers between 08/18/2017 and 09/01/2017

Stereo Investigator:journal images sm

Balu, D. T., Presti, K. T., Huang, C. C. Y., Muszynski, K., Radzishevsky, I., Wolosker, H., . . . Coyle, J. T. (2017). Serine Racemase and D-serine in the Amygdala are Dynamically Involved in Fear Learning. Biological Psychiatry. doi: 10.1016/j.biopsych.2017.08.012.

Boulanger, J. J., & Messier, C. (2017). Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex: Unbiased stereological analysis. Neuroscience. doi: http://dx.doi.org/10.1016/j.neuroscience.2017.08.018.

Farrand, A. Q., Helke, K. L., Gregory, R. A., Gooz, M., Hinson, V. K., & Boger, H. A. (2017). Vagus nerve stimulation improves locomotion and neuronal populations in a model of Parkinson’s disease. Brain Stimulation. doi: https://doi.org/10.1016/j.brs.2017.08.008.

Figueiredo, T. H., Harbert, C. L., Pidoplichko, V., Almeida-Suhett, C. P., Pan, H., Rossetti, K., . . . Marini, A. M. (2017). Alpha-Linolenic Acid Treatment Reduces the Contusion and Prevents the Development of Anxiety-Like Behavior Induced by a Mild Traumatic Brain Injury in Rats.  Molecular Neurobiology. doi: 10.1007/s12035-017-0732-y.

Guan, J., Yang, B., Fan, Y., & Zhang, J. (2017). GPER Agonist G1 Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson Disease. Neuroimmunomodulation, 0(0), 60-66.

Loris, Z. B., Hynton, J. R., Pieper, A. A., & Dietrich, W. D. (2017). Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats. Translational Stroke Research. doi: 10.1007/s12975-017-0565-z.

Continue reading “Researchers cited MBF Bioscience systems in 27 papers between 08/18/2017 and 09/01/2017” »