January 10, 2006
Kim AT, Li S, Kim Y, You YJ, Park Y.
Activation or inhibition of opioid and cannabinoid receptors bidirectionally alters food preference in C. elegans. The assay enables behavior-based screening of candidate effectors. ... Read More
MBF Bioscience News
January 10, 2006
Maryam B, Wang Y, Li X, Asim M, Qayyum H, Zhang P, Liu X.
Tracking micro- and nanoplastic ingestion in living organisms remains technically challenging. This study introduces upconverted nanoparticles as high-sensitivity probes to reveal size-dependent plastic toxicity in C. elegans.... Read More
January 10, 2006
Cordeiro LM, Soares MV, da Silva AF, Dos Santos LV, de Souza LI, da Silveira TL, Baptista FBO, de Oliveira GV, Pappis C, Dressler VL, Arantes LP, Zheng F, Soares FAA.
Metal mixtures exacerbate neuronal dysfunction and Huntington’s disease–like phenotypes in a nematode model. A dietary flavonoid counteracts aggregation and neurodegeneration.... Read More
January 10, 2006
Gu Y, Jiang Y, Chen X, Li L, Chen H, Chen J, Wang C, Yu J, Chen C, Li H.
Free radicals formed during tire particle photoaging impair neurotransmitter balance and locomotion. Radical scavenging reverses these effects, implicating EPFRs as key toxic agents. ... Read More
January 10, 2006
Currie SD, Ji Y, Huang Q, Wang JS, Tang L.
Early-life exposure to PFAS disrupts learning and memory in a dose-dependent manner. This study links neurobehavioral impairment to PFAS bioaccumulation in C. elegans. ... Read More
January 10, 2006
Munasinghea M, Almotayria A, Thomasa J, Heydariana D, Weerasingheb M, Joisa M.
Dietary cocoa supplementation improves healthspan and modestly extends lifespan. In C. elegans, cocoa enhances neuromuscular, cognitive, and mitochondrial function during aging. ... Read More
January 3, 2006
Jacobsen NL, Norton CE, Shaw RL, Cornelison DDW, Segal SS.
Skeletal muscle injury triggers profound but reversible disruption of the capillary network. This study reveals how microvessels regenerate through a transient, disorganized phase before restoring normal architecture. ... Read More
January 2, 2006
Hrvatin S, Sun S, Wilcox OF, Yao H, Lavin-Peter AJ, Cicconet M, Assad EG, Palmer ME, Aronson S, Banks AS, Griffith EC, Greenberg ME.
Glutamatergic Adcyap1-positive neurons in the preoptic hypothalamus drive fasting-induced torpor. Activating these neurons alone is sufficient to induce hypothermia and inactivity.... Read More
January 2, 2006
Barik A, Sathyamurthy A, Thompson J, Seltzer M, Levine A, Chesler A.
A defined spinoparabrachial Tacr1 circuit selectively signals sustained, but not acute, noxious stimuli. Activation of this pathway amplifies pain while suppressing itch. ... Read More
January 2, 2006
Flanigan, M.E., Aleyasin, H., Li, L. et al.
Aggression can be intrinsically rewarding and is shaped by specific brain circuits. This study identifies an orexin-sensitive inhibitory microcircuit in the lateral habenula that promotes aggression and its rewarding properties. ... Read More