December 19, 2006
Bar-Noam AS, Farah N, Shoham S.
A model-guided two-photon optical design enables high-resolution retinal imaging and functional calcium recordings without the need for adaptive optics.... Read More
MBF Bioscience News
December 19, 2006
Bakker GJ, Weischer S, Ferrer Ortas J, Heidelin J, Andresen V, Beutler M, Beaurepaire E, Friedl P.
A multiphoton imaging approach using infrared excitation enables non-invasive, deep-tissue visualization with preserved resolution in highly scattering tissues.... Read More
December 19, 2006
Wang K, Pan Y, Tong S, Liang H, Qiu P.
Multiphoton excitation at 1700 nm enables high-resolution visualization of lymphatic structure and dynamics in strongly scattering skin tissue.... Read More
December 19, 2006
Heiser H, Kiessler F, Roggenbach A, Ibanez V, Wieckhorst M, Helmchen F, Gjorgjieva J, Wahl AS.
Chronic two-photon imaging reveals that loss of stable hippocampal place cells underlies memory impairment following microvascular injury.... Read More
December 19, 2006
Vallentin D, Kosche G, Lipkind D, Long MA.
Two-photon–guided electrophysiology reveals that inhibitory synaptic activity increases with song learning and suppresses sensory input to HVC premotor neurons.... Read More
December 19, 2006
Cox J, Pinto L, Dan Y.
Cell-type-specific calcium imaging revealed distinct and spatially organized activity patterns in the dorsal pons across sleep–wake states. Glutamatergic neurons were predominantly active during REM sleep, while GABAergic neurons were biased toward wakefulness, highlighting specialized subpopulations involved in sleep regulation.... Read More
December 19, 2006
Yang W, Miller JE, Carrillo-Reid L, Pnevmatikakis E, Paninski L, Yuste R, Peterka DS.
A holographic two-photon imaging system enables simultaneous multi-plane recording of neuronal activity across cortical layers with single-cell precision. Multiplexed excitation and synchronized acquisition capture fast, correlated calcium dynamics beyond the limits of sequential two-photon scanning.... Read More
December 19, 2006
Zhao S, Hebert E, Gruzdeva A, Mahishi D, Takahashi H, Lee S, Hao YA, Lin MZ, Yapici N, Xu C.
Adaptive excitation enables high-speed, deep two-photon voltage imaging of multiple neurons while staying below tissue heating limits. By boosting signal collection and supporting simultaneous dual-plane recordings, this approach captures rapid neuronal activity at depths and speeds not achievable with conventional two-photon microscopy.... Read More
December 19, 2006
Mok AT, Wang T, Zhao S, Kolkman KE, Wu D, Ouzounov DG, Seo C, Wu C, Fetcho JR, Xu C.
An integrated multiphoton system enabled large field-of-view, single-cell imaging deep into cortical and subcortical regions. Simultaneous two- and three-photon imaging captured activity across thousands of neurons, extending depth and coverage beyond conventional approaches.... Read More
December 19, 2006
Yu CH, Stirman JN, Yu Y, Hira R, Smith SL.
A dual-engine two-photon mesoscope enabled high-resolution, simultaneous imaging across widely separated cortical regions. Independent scan control and adaptive optics supported flexible, large-scale recording of thousands of neurons in vivo, overcoming traditional field-of-view limitations in two-photon microscopy.... Read More