June 23, 2026
The article discusses how HySIL addresses longstanding challenges in volumetric imaging by combining inexpensive long-working-distance air objectives with hybrid solid–liquid optics....
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Microscopy Imaging Systems
June 4, 2026
MBF Bioscience and Columbia University advance accessible 3D imaging through SLICE and SCOPE, enabling scalable, high-resolution light-sheet microscopy....
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May 20, 2026
A recent article in BioPhotonics magazine highlights how the SLICE Light Sheet Microscope is making high-performance whole-brain imaging more accessible....
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March 13, 2026
A new peer-reviewed study describes the design and capabilities of ClearScope®, MBF Bioscience's fully integrated light-sheet theta microscope for high-resolution 3D imaging of large biological specimens without lateral size constraints. Reference Fay, M. G., Lang, P. J., Denu, D. S., et al. (2026). ClearScope: A Fully Integrated Light-Sheet Theta Microscope for Sub-Micron-Resolution Imaging Without Lateral Size Constraints. Journal of Imaging. https://doi.org/10.3390/jimaging12030118 Background Three-dimensional imaging of intact organs and large...
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August 18, 2025
FOR IMMEDIATE RELEASE WILLISTON, VT – August 18, 2025 – MBF Bioscience today proudly announces that its revolutionary light sheet microscope, SLICE™, has been awarded a Microscopy Today Innovation Award. This prestigious recognition celebrates SLICE as a game-changing solution that is transforming the light sheet microscopy landscape by delivering superior performance at an exceptionally accessible price point, democratizing advanced 3D imaging and empowering laboratories of all sizes...
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July 24, 2025
In our recent discussions, we've introduced SLICE as a revolutionary light sheet microscope, making high-performance 3D imaging accessible for under $99,000. We've highlighted its integrated BrightSLICE software and transparent $5,000 annual support. For many, such claims might raise a natural question: how can a system that costs so much less also deliver superior image quality and a better overall experience than those multi-hundred-thousand-dollar legacy machines? This...
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July 7, 2025
For years, light sheet microscopy has stood out as a powerful technique, enabling stunning 3D imaging of large, live, and delicate biological samples. Its unique ability to provide deep tissue penetration with minimal phototoxicity has driven significant discoveries across neuroscience, developmental biology, and beyond. However, the path to acquiring this cutting-edge technology has been steep for most. High-end legacy light sheet systems often come with instrument...
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June 9, 2025
FOR IMMEDIATE RELEASE MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up Breakthrough system combines high performance with unprecedented affordability and compact design, making cutting-edge light sheet microscopy accessible to labs of all sizes WILLISTON, VT – June 9, 2025 – MBF Bioscience, a world leader in quantitative microscopy solutions, today announced the commercial launch of SLICE™, a revolutionary light sheet microscope that represents...
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December 19, 2024
We are pleased to announce the release of Microlucida®version 2024.1.3, which introduces key updates to offline software licensing. These updates enhance the functionality and ensure uninterrupted use of the software on systems without internet access....
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October 2, 2024
Throughout my career, I've been driven by a singular goal: to advance scientific research by making cutting-edge tools accessible to researchers worldwide. Today, I'm thrilled to share news that I believe will significantly impact our field. In just a few days, at the Society for Neuroscience meeting in Chicago, we will be unveiling SLICE – our new affordable light sheet microscope that truly redefines what's possible...
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