Wei L, Simen A, Mane S, Kaffman A.
Early life stress suppressed LBP expression in the developing hippocampus and led to increased spine density, abnormal spine structure and impaired cognition in adulthood. LBP knockout mice showed similar synaptic and behavioral abnormalities, indicating LBP’s role in microglia-mediated synaptic refinement.... Read More
Papp T, Ferenczi Z, Szilagyi B, Petro M, Varga A, Kókai E, Berenyi E, Olah G, Halmos G, Szucs P, Meszar Z.
Diagnostic-level ultrasound modestly increases basal dendritic branching and activates mechanosensitive signaling pathways in developing cortical neurons, with repeated exposure amplifying markers of neuronal activation.... Read More
Glaser JR, Glaser EM.
Neurolucida brings precise 3D neuron tracing and morphometry to standard personal computers through integrated stage control, image combination and interactive graphics.... Read More
Van der Loos H, Glaser EM.
Neocortical pyramidal neurons can form autapses, self-synaptic loops onto their own basal dendrites that may provide a localized feedback mechanism for modulating excitatory drive.... Read More
Glaser EM, Van der Loos H.
A computerized light-microscopy system that recorded 3D coordinates and performed real-time geometric calculations enabled fast, accurate measurement of Golgi-stained neurons. The platform cut analysis time from ~24 hours to ~45 minutes and produced reproducible micron-scale measurements.... Read More