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Something big is happening at MBF Bioscience. Something that will make your work better than ever before. Over the past 32 years we have taken pride in offering our customers the best tools for their research. And we are constantly striving to make things even better for you. Get ready, because something extraordinary is coming in 2020. Something that will make your work faster and more efficient....

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Every year, we look forward to showcasing our new products and latest developments at the Society for Neuroscience’s annual meeting. This year, from November 3 – 7, we’ll be at SfN 2018 in San Diego, at Booth #2235, where our team of expert scientists and engineers will be on hand to offer personalized demonstrations of all of our products.

This year, we are thrilled to introduce two major new software solutions: Vesselucida 360, an application for reconstructing microvascular networks in 3D, and NeuroInfo for automatic identification of brain anatomy in your sections.

We are also excited to showcase the following:

➛ Software and systems

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The SfN 2017 meeting is the culmination of an exciting year of new technological achievements at MBF Bioscience. Our new version 2017 of Neurolucida, Stereo Investigator, and Neurolucida 360 features a totally re-designed interface and has been an overwhelming success with our customers. We've also expanded the stereology family with Stereo Investigator Cleared Tissue edition and Stereo Investigator Whole Slide Imaging edition. And we have...

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Stereo Investigator:journal images sm

Acker, S. N., Mandell, E. W., Sims-Lucas, S., Gien, J., Abman, S. H., & Galambos, C. (2014). Histologic Identification of Prominent Intrapulmonary Anastomotic Vessels in Severe Congenital Diaphragmatic Hernia. The Journal of Pediatrics(0).

Dixon, K. J., Theus, M. H., Nelersa, C. M., Mier, J., Travieso, L. G., Yu, T.-S., . . . Liebl, D. J. (2014). Endogenous neural stem/progenitor cells stabilize the cortical microenvironment following traumatic brain injury. Journal of Neurotrauma.

Janelidze, S., Nordström, U., Kügler, S., & Brundin, P. (2014). Pre‐existing immunity to AAV2 limits transgene expression following intracerebral AAV2‐based gene delivery in a 6‐OHDA model of Parkinson’s disease. The Journal of Gene Medicine.

Le Belle, Janel E., Sperry, J., Ngo, A., Ghochani, Y., Laks, D. R., López-Aranda, M., . . . Kornblum, Harley I. (2014). Maternal Inflammation Contributes to Brain Overgrowth and Autism-Associated Behaviors through Altered Redox Signaling in Stem and Progenitor Cells. Stem Cell Reports(0).

Polinski, N. K., Gombash, S. E., Manfredsson, F. P., Lipton, J. W., Kemp, C. J., Cole-Strauss, A., . . . Sortwell, C. E. (2014). Recombinant adeno-associated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain. Neurobiology of Aging. doi: 10.1016/j.neurobiolaging.2014.07.047

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Stereo Investigator:journal images sm

Barkan, S., Yom-Tov, Y., & Barnea, A. (2014). A possible relation between new neuronal recruitment and migratory behavior in Acrocephalus warblers. Developmental Neurobiology, n/a-n/a. doi: 10.1002/dneu.22198.

Bethea, C. L., Coleman, K., Phu, K., Reddy, A. P., & Phu, A. (2014). Relationships between androgens, serotonin gene expression and innervation in male macaques. Neuroscience(0).

Coimbra, J. P., Collin, S. P., & Hart, N. S. (2014). Topographic specializations in the retinal ganglion cell layer correlate with lateralized visual behavior, ecology and evolution in cockatoos. Journal of Comparative Neurology, n/a-n/a. doi: 10.1002/cne.23637.

Dellarole, A., Morton, P., Brambilla, R., Walters, W., Summers, S., Bernardes, D., . . . Bethea, J. R. (2014). Neuropathic pain-induced depressive-like behavior and hippocampal neurogenesis and plasticity are dependent on TNFR1 signaling. Brain, Behavior, and Immunity(0).

Höfling, C., Indrischek, H., Höpcke, T., Waniek, A., Cynis, H., Koch, B., . . . Hartlage-Rübsamen, M. (2014). Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC. International Journal of Developmental Neuroscience(0).

Koh, M. T., Spiegel, A. M., & Gallagher, M. (2014). Age-associated changes in hippocampal-dependent cognition in Diversity Outbred mice. Hippocampus, n/a-n/a. doi: 10.1002/hipo.22311.

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Stereo Investigator:

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Akers, K. G., Martinez-Canabal, A., Restivo, L., Yiu, A. P., De Cristofaro, A., Hsiang, H.-L. L., . . . Shoji, H. (2014). Hippocampal Neurogenesis Regulates Forgetting During Adulthood and Infancy. Science, 344(6184), 598-602.

Burger, D. K., Gulbrandsen, T., Saucier, D. M., & Iwaniuk, A. N. (2014). The effects of season and sex on dentate gyrus size and neurogenesis in a wild rodent, Richardson’s ground squirrel (Urocitellus richardsonii). Neuroscience(0).

Coimbra, J. P., Collin, S. P., & Hart, N. S. (2014). Topographic specializations in the retinal ganglion cell layer of Australian passerines. Journal of Comparative Neurology, n/a-n/a. doi: 10.1002/cne.23624.

Fernando, C., Kele, J., Bye, C., Niclis, J. C., Alsanie, W., Blakely, B. D., . . . Parish, C. (2014). Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis. Stem Cells and Development(ja).

Gombash, S., Manfredsson, F., Mandel, R., Collier, T., Fischer, D., Kemp, C., . . . Sortwell, C. (2014). Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Therapy.

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journal images smStereo Investigator:

Drury, P. P., Davidson, J. O., Mathai, S., van den Heuij, L. G., Ji, H., Bennet, L., . . . Gunn, A. J. (2014). nNOS inhibition during profound asphyxia reduces seizure burden and improves survival of striatal phenotypic neurons in preterm fetal sheep. Neuropharmacology.

Liu, X., Zhou, J., Abid, M. D. N., Yan, H., Huang, H., Wan, L., . . . Chen, J. (2014). Berberine Attenuates Axonal Transport Impairment and Axonopathy Induced by Calyculin A in N2a Cells. Plos one, 9(4), e93974. doi: 10.1371/journal.pone.0093974.

Smith, G. A., Rocha, E. M., McLean, J. R., Hayes, M. A., Izen, S. C., Isacson, O., & Hallett, P. J. (2014). Progressive axonal transport and synaptic protein changes correlate with behavioral and neuropathological abnormalities in the heterozygous Q175 KI mouse model of Huntington’s disease. Human Molecular Genetics. doi: 10.1093/hmg/ddu166.

Zhang, J., Saur, T., Duke, A. N., Grant, S. G. N., Platt, D. M., Rowlett, J. K., . . . Yao, W.-D. (2014). Motor Impairments, Striatal Degeneration, and Altered Dopamine-Glutamate Interplay in Mice Lacking PSD-95. Journal of Neurogenetics, 0(ja), 1-26. doi: doi:10.3109/01677063.2014.892486.


Cerri, S., Levandis, G., Ambrosi, G., Montepeloso, E., Antoninetti, G. F., Franco, R., . . . Pinna, A. (2014). Neuroprotective Potential of Adenosine A2A and Cannabinoid CB1 Receptor Antagonists in an Animal Model of Parkinson Disease. Journal of Neuropathology and Experimental Neurology.

Gyengesi, E., Mnch, G., Paxinos, G., & Zaborszky, L. (2014). Can you believe what you see: evaluation of choline acetyl transferase (ChAT) expression in the ChAT-eGFP transgenic mouse (89.1). The FASEB journal, 28(1 Supplement).

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Microsoft announced that it will discontinue support for Windows XP on April 8th, 2014. After this date, there will be no new security updates and your lab may be exposed to potential security risks and viruses. If you have an MBF system that runs on Windows XP, please be aware that older cameras and stages might not be compatible with newer Windows operating systems. Please contact us at info@mbfbioscience.com or...

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MBF Bioscience will be at the 19th International C. elegans meeting from Thrusday, June 27 to Saturday, June 29, at the University of California, Los Angeles. Visit booth #110 to talk to our worm tracking experts and to try out the latest tools for worm tracking. We will have the latest version of WormLab to easily track the behavior of your worms and our new plate...

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Our systems were mentioned in 22 published research papers last week alone.  Take a closer look at some of the research…


  • Albrecht, P. J., Hou, Q., Argoff, C. E., Storey, J. R., Wymer, J. P., & Rice, F. L. (2013). Excessive Peptidergic Sensory Innervation of Cutaneous Arteriole–Venule Shunts (AVS) in the Palmar Glabrous Skin of Fibromyalgia Patients: Implications for Widespread Deep Tissue Pain and Fatigue. Pain Medicine. doi: 10.1111/pme.12139
  • Bessa, S., Quelhas, P., & Amaral, I. F. (2013). Automatic Quantification of Cell Outgrowth from Neurospheres. In Pattern Recognition and Image Analysis (pp. 141-148). Springer Berlin Heidelberg. doi: 10.1007/978-3-642-38628-2_16
  • Coddington, L. T., Rudolph, S., Vande Lune, P., Overstreet-Wadiche, L., & Wadiche, J. I. (2013). Spillover-Mediated Feedforward Inhibition Functionally Segregates Interneuron Activity. Neuron. doi: 10.1016/j.neuron.2013.04.019
  • deCampo, D. M., & Fudge, J. L. (2013). Amygdala projections to the lateral bed nucleus of the stria terminalis in the macaque: Comparison with ventral striatal afferents. Journal of Comparative Neurology. doi: 10.1002/cne.23340                 
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