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MBF Products & Service Solutions

MBF Bioscience >  Blog > MBF Products & Service Solutions (Page 16)
May 13, 2010

Multiple Sclerosis and Schizophrenia Research May Benefit From New Findings

by Pasang
in Software Applications For Quantitive Analysis, Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Neurolucida®Explorer
Comments

Myelin, which insulates axons in the central nervous system is produced by oligodendrocytes. But not all oligodendrocytes are equal.   Led by Dr. Jonathan Vinet of the Université Laval in Quebec, scientists have identified three different types of oligodendrocytes in the mouse hippocampus: "ramified," "stellar," and "smooth."   Each type displayed varying morphological characteristics, mainly in shape, volume, and branching behavior, which led the researchers to believe that the...

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April 28, 2010

Swiss Scientists Use Stereo Investigator to Study Schizophrenia

by Pasang
in Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Stereology
Comments

There may be more evidence that schizophrenia results from a combination of genetic and environmental factors. One of these hereditary influences may be an impaired ability to synthesize the antioxidant glutathione (GSH), which results in oxidative stress, according to a study conducted by scientists at the University of Lausanne in Switzerland.   By observing mice with a GSH deficit, Dr. Kim Q. Do and her team determined...

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March 25, 2010

University of Maryland Scientists Reconstruct Neuronal Processes in 3D with Neurolucida

by Pasang
in Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction
Comments

University of Maryland School of Medicine researchers have used Neurolucida since it was in its embryonic stages in the 1960s. Now, nearly a half-century later, the Department of Anatomy and Neurobiology continues using Neurolucida in their research, as outlined in a recent study concerning the organization of the olfactory system. Dr. Michael Shipley and his team collaborated with scientists from Hungary and Japan on the paper...

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March 1, 2010

Stereo Investigator Aids in Researching Familial Alzheimer’s Disease

by Pasang
in Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Additional Subject Matter, Alzheimer’s Disease, Stereology
Comments

Alzheimer's disease is the most common form of dementia. Most cases occur in people over 65, and are not genetically inherited. Roughly five percent of Alzheimer's patients suffer from familial Alzheimer's disease (FAD), an uncommon form that tends to strike sooner, and is related to a genetic predisposition - most commonly, a mutation in the presenilin 1 gene (PS1).   A recent study, led by Dr. Miguel...

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February 9, 2010

Neurolucida Helps Scientists Better Understand Sound Localization

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction, Neuron Reconstruction
Comments

Birds and mammals hear binaurally, hearing sounds through two ears. Binaural hearing allows them to determine which direction a sound came from—a pivotal element of survival.   Doctors Armin H. Seidl, Edwin W. Rubel, and David M. Harris of Seattle’s Virginia Merrill Bloedel Hearing Research Center at the University of Washington recently published a study in the Journal of Neuroscience that may encourage scientists to think in...

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December 18, 2009

UVM Awarded $1 Million Grant for Nicotine Research

by Pasang
in Neurolucida®, Company News, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Additional Subject Matter
Comments

  If you start smoking as a teen, it’s much harder to quit. University of Vermont Neurobiologist Rae Nishi wants to find out why. And thanks to a $1 million Challenge Grant, Nishi and her team will be able to further study the way adolescent brains react to nicotine.   The grant is one of 200 National Institute of Health grants allocated by the American Recovery and Reinvestment...

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November 24, 2009

Neurolucida, NeuroInfo Aids NIH GENSAT Project

by Pasang
in Software Applications For Quantitive Analysis, Neurolucida®, Software & Microscope Integrated Systems, MBF Products & Service Solutions, NeuroInfo®
Comments

The developing and adult central nervous system of the mouse is complex and large. NIH Neuroscientist Dr. Charles Gerfen uses Neurolucida and NeuroInfo to collect, display, and share virtual slides with the research community.   Recently, Dr. Gerfen requested software enhancements to better allow him to categorize and use his virtual slide data in mouse brain testing. We were happy to comply.   Dr. Gerfen explains how he uses...

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September 30, 2009

Stem Cell Transplants Aid in Spinal Recovery

by Pasang
in Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, Stem Cell Research, Stereology
Comments

Thousands of people in the United States have spinal cord injuries (SCIs), with associated loss of movement and sensation below the site of the injury. Neural and glial cell transplants into research animals after SCI have correlated with recovery of function. The improvement may be caused by the transplanted cells; it’s thought that remyelination by the transplanted glial cells is the main reason for the...

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September 1, 2008

Using Neurolucida for Dendritic Spine Analysis

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Dendritic Spines
Comments

Neurolucida is used for reconstruction and morphometric analysis of neurons and anatomical regions of interest. Neurolucida can also be used for quantitative and qualitative analysis of dendritic spines. Spines are small, often bulbous protrusions that emerge from the dendritic shaft. They are the main site of excitatory synapses in the brain [1], and they range in length from 0.001 to 1mm and range in diameter...

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June 7, 2008

Pulmonary Edition of Stereo Investigator Now Available

by Pasang
in Software & Microscope Integrated Systems, Stereo Investigator®, Scientific Applications & Use Cases, MBF Products & Service Solutions, Stereology
Comments

Stereo Investigator Pulmonary Edition, our latest stereology software solution, is designed specifically to assist pulmonary researchers with quantitative stereological analysis. Stereo Investigator Pulmonary Edition introduces the Connectivity Assay. Using live video superimposed over captured images, pulmonary researchers can quickly mark bridges and islands.   "Whether you’re counting alveoli or quantifying cells, lengths, or volumes, Stereo Investigator Pulmonary Edition’s intuitive workflow technology simplifies stereology," said MBF Bioscience President...

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