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Anthropic ScanImage research preview

We're adding native support for the Model Hardware Standard (MHS) in ScanImage as part of the MHS research preview. MHS is a new standard for AI agents to safely operate physical equipment in scientific research and advanced manufacturing. During the preview, we're testing how MHS-compatible agents operate ScanImage within device-declared safety bounds.   Why we’re doing this A two-photon experiment often involves several components: a microscope, behavioral hardware for stimulus and reward delivery, video systems, and other devices. Running a successful...

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A new peer-reviewed study describes the design and capabilities of ClearScope®, MBF Bioscience's fully integrated light-sheet theta microscope for high-resolution 3D imaging of large biological specimens without lateral size constraints.   Reference Fay, M. G., Lang, P. J., Denu, D. S., et al. (2026). ClearScope: A Fully Integrated Light-Sheet Theta Microscope for Sub-Micron-Resolution Imaging Without Lateral Size Constraints. Journal of Imaging. https://doi.org/10.3390/jimaging12030118   Background Three-dimensional imaging of intact organs and large...

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FOR IMMEDIATE RELEASE   WILLISTON, VT – August 18, 2025 – MBF Bioscience today proudly announces that its revolutionary light sheet microscope, SLICE, has been awarded a Microscopy Today Innovation Award. This prestigious recognition celebrates SLICE as a game-changing solution that is transforming the light sheet microscopy landscape by delivering superior performance at an exceptionally accessible price point, democratizing advanced 3D imaging and empowering laboratories of all sizes...

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In our recent discussions, we've introduced SLICE as a revolutionary light sheet microscope, making high-performance 3D imaging accessible for under $99,000. We've highlighted its integrated BrightSLICE software and transparent $5,000 annual support. For many, such claims might raise a natural question: how can a system that costs so much less also deliver superior image quality and a better overall experience than those multi-hundred-thousand-dollar legacy machines?   This...

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For years, light sheet microscopy has stood out as a powerful technique, enabling stunning 3D imaging of large, live, and delicate biological samples. Its unique ability to provide deep tissue penetration with minimal phototoxicity has driven significant discoveries across neuroscience, developmental biology, and beyond.   However, the path to acquiring this cutting-edge technology has been steep for most. High-end legacy light sheet systems often come with instrument...

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FOR IMMEDIATE RELEASE   MBF Bioscience Introduces SLICE: We Reimagined Light Sheet Microscopes From the Ground Up   Breakthrough system combines high performance with unprecedented affordability and compact design, making cutting-edge light sheet microscopy accessible to labs of all sizes   WILLISTON, VT – June 9, 2025 – MBF Bioscience, a world leader in quantitative microscopy solutions, today announced the commercial launch of SLICE, a revolutionary light sheet microscope that represents...

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MBF Bioscience and Phaseform are delighted to announce a breakthrough collaboration that integrates Phaseform’s advanced Adaptive Optics (AO) solutions into MBF Bioscience’s renowned ScanImage software for multiphoton and laser scanning microscopes. This joint development opens the door for researchers across neuroscience, developmental biology, cancer research, and other fields to achieve unmatched image clarity and depth, all while preserving their existing microscopy workflows.   Seamless Adaptive Optics...

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