Researchers cited MBF Bioscience systems in 27 papers between 08/18/2017 and 09/01/2017

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Balu, D. T., Presti, K. T., Huang, C. C. Y., Muszynski, K., Radzishevsky, I., Wolosker, H., . . . Coyle, J. T. (2017). Serine Racemase and D-serine in the Amygdala are Dynamically Involved in Fear Learning. Biological Psychiatry. doi: 10.1016/j.biopsych.2017.08.012.

Boulanger, J. J., & Messier, C. (2017). Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex: Unbiased stereological analysis. Neuroscience. doi: http://dx.doi.org/10.1016/j.neuroscience.2017.08.018.

Farrand, A. Q., Helke, K. L., Gregory, R. A., Gooz, M., Hinson, V. K., & Boger, H. A. (2017). Vagus nerve stimulation improves locomotion and neuronal populations in a model of Parkinson’s disease. Brain Stimulation. doi: https://doi.org/10.1016/j.brs.2017.08.008.

Figueiredo, T. H., Harbert, C. L., Pidoplichko, V., Almeida-Suhett, C. P., Pan, H., Rossetti, K., . . . Marini, A. M. (2017). Alpha-Linolenic Acid Treatment Reduces the Contusion and Prevents the Development of Anxiety-Like Behavior Induced by a Mild Traumatic Brain Injury in Rats.  Molecular Neurobiology. doi: 10.1007/s12035-017-0732-y.

Guan, J., Yang, B., Fan, Y., & Zhang, J. (2017). GPER Agonist G1 Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson Disease. Neuroimmunomodulation, 0(0), 60-66.

Loris, Z. B., Hynton, J. R., Pieper, A. A., & Dietrich, W. D. (2017). Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats. Translational Stroke Research. doi: 10.1007/s12975-017-0565-z.

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Researchers cited MBF systems in 25 papers between 5/16/2017 and 5/26/2017

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Baxter, V. K., Glowinski, R., Braxton, A. M., Potter, M. C., Slusher, B. S., & Griffin, D. E. (2017). Glutamine antagonist-mediated immune suppression decreases pathology but delays virus clearance in mice during nonfatal alphavirus encephalomyelitis. Virology, 508, 134-149. doi: https://doi.org/10.1016/j.virol.2017.05.013.

Brzozowska, N. I., Smith, K. L., Zhou, C., Waters, P. M., Cavalcante, L. M., Abelev, S. V., . . . Arnold, J. C. (2017). Genetic deletion of P-glycoprotein alters stress responsivity and increases depression-like behavior, social withdrawal and microglial activation in the hippocampus of female mice. Brain, Behavior, and Immunity. doi: https://doi.org/10.1016/j.bbi.2017.05.008.

Chareyron, L. J., Banta Lavenex, P., Amaral, D. G., & Lavenex, P. (2017). Functional organization of the medial temporal lobe memory system following neonatal hippocampal lesion in rhesus monkeys. Brain Structure and Function, 1-16. doi: 10.1007/s00429-017-1441-z.

Kwan, T., Floyd, C. L., Patel, J., Mohaimany-Aponte, A., & King, P. H. (2017). Astrocytic expression of the RNA regulator HuR accentuates spinal cord injury in the acute phase. Neuroscience Letters, 651, 140-145. doi: https://doi.org/10.1016/j.neulet.2017.05.003.

Newville, J., Valenzuela, C. F., Li, L., Jantzie, L. L., & Cunningham, L. A. (2017). Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder. Glia, n/a-n/a. doi: 10.1002/glia.23164.

Onger, M. E., Kaplan, S., Geuna, S., Türkmen, A. P., Muratori, L., Altun, G., & Altunkaynak, B. Z. (2017). Possible effects of some agents on the injured nerve in obese rats: A stereological and electron microscopic study. Journal of Cranio-Maxillofacial Surgery. doi: https://doi.org/10.1016/j.jcms.2017.05.004.

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Researchers cited MBF systems in 14 papers between 1/20/2017 and 1/27/2017

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Doerr, J., Schwarz, M. K., Wiedermann, D., Leinhaas, A., Jakobs, A., Schloen, F., . . . Brüstle, O. (2017). Whole-brain 3D mapping of human neural transplant innervation. Nature Communications, 8, 14162. doi: 10.1038/ncomms14162

Fields, J. A., Metcalf, J., Overk, C., Adame, A., Spencer, B., Wrasidlo, W., . . . Masliah, E. (2017). The anticancer drug sunitinib promotes autophagyand protects from neurotoxicity in an HIV-1 Tat model of neurodegeneration. Journal of Neurovirology, 1-14. doi: 10.1007/s13365-016-0502-z.

Haidar, M., Guèvremont, G., Zhang, C., Bathgate, R. A. D., Timofeeva, E., Smith, C. M., & Gundlach, A. L. (2017). Relaxin-3 Inputs Target Hippocampal Interneurons and Deletion of Hilar Relaxin-3 Receptors in ‘Floxed-RXFP3′ Mice Impairs Spatial Memory. Hippocampus, n/a-n/a. doi: 10.1002/hipo.22709.

Kelly, S. C., He, B., Perez, S. E., Ginsberg, S. D., Mufson, E. J., & Counts, S. E. (2017). Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease. Acta Neuropathologica Communications, 5(1), 8. doi: 10.1186/s40478-017-0411-2.

Shen, X.-L., Song, N., Du, X.-X., Li, Y., Xie, J.-X., & Jiang, H. (2017). Nesfatin-1 protects dopaminergic neurons against MPP+/MPTP-induced neurotoxicity through the C-Raf–ERK1/2-dependent anti-apoptotic pathway. Scientific Reports, 7, 40961. doi: 10.1038/srep40961

Turner, R. C., Naser, Z. J., Lucke-Wold, B. P., Logsdon, A. F., Vangilder, R. L., Matsumoto, R. R., . . . Rosen, C. L. (2017). Single low-dose lipopolysaccharide preconditioning: neuroprotective against axonal injury and modulates glial cells. [Lipopolysaccharide preconditioning, oncostatin M receptor, diffuse axonal injury, gliosis, neuroprotection]. Neuroimmunology and Neuroinflammation, 4(1), 6-15.

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Researchers cited MBF systems in 25 papers between 1/13/2017 and 1/20/2017

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Allegra, M., Spalletti, C., Vignoli, B., Azzimondi, S., Busti, I., Billuart, P., . . . Caleo, M. (2017). Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability. Neurobiology of Disease, 100, 75-86.

Anan, J., Hijioka, M., Kurauchi, Y., Hisatsune, A., Seki, T., & Katsuki, H. (2017). Cortical hemorrhage-associated neurological deficits and tissue damage in mice are ameliorated by therapeutic treatment with nicotine. Journal of Neuroscience Research, n/a-n/a. doi: 10.1002/jnr.24016.

Ardestani, P. M., Evans, A. K., Yi, B., Nguyen, T., Coutellier, L., & Shamloo, M. (2017). Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer’s disease using a biased and selective beta-1 adrenergic receptor partial agonist. Neuropharmacology.

Estrada, L. I., Robinson, A. A., Amaral, A. C., Giannaris, E. L., Heyworth, N. C., Mortazavi, F., . . . Rosene, D. L. (2017). Evaluation of Long-Term Cryostorage of Brain Tissue Sections for Quantitative Histochemistry. Journal of Histochemistry and Cytochemistry, 0022155416686934. doi: 10.1369/0022155416686934.

Klocke, C., Allen, J. L., Sobolewski, M., Mayer-Pröschel, M., Blum, J. L., Lauterstein, D., . . . Cory-Slechta, D. A. (2017). Neuropathological Consequences of Gestational Exposure to Concentrated Ambient Fine and Ultrafine Particles in the Mouse. Toxicological Sciences. doi: 10.1093/toxsci/kfx010.

Loris, Z. B., Pieper, A. A., & Dalton Dietrich, W. (2017). The neuroprotective compound P7C3-A20 promotes neurogenesis and improves cognitive function after ischemic stroke. Experimental Neurology, 290, 63-73. doi: http://dx.doi.org/10.1016/j.expneurol.2017.01.006.

Luo, L., Chen, J., Su, D., Chen, M., Luo, B., Pi, R., . . . Wang, R. (2017). L-F001, a Multifunction ROCK Inhibitor Prevents 6-OHDA Induced Cell Death Through Activating Akt/GSK-3beta and Nrf2/HO-1 Signaling Pathway in PC12 Cells and Attenuates MPTP-Induced Dopamine Neuron Toxicity in Mice. Neurochemical Research, 1-10. doi: 10.1007/s11064-016-2117-4.

Moore, B. A., Tyrrell, L. P., Pita, D., Bininda-Emonds, O. R. P., & Fernández-Juricic, E. (2017). Does retinal configuration make the head and eyes of foveate birds move? . Scientific Reports, 7, 38406. doi: 10.1038/srep38406

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Researchers cited MBF systems in 16 papers between 11/1/2016 and 11/11/2016

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Bode, C., Richter, F., Spröte, C., Brigadski, T., Bauer, A., Fietz, S., . . . Richter, A. (2017). Altered postnatal maturation of striatal GABAergic interneurons in a phenotypic animal model of dystonia. Experimental Neurology, 287, Part 1, 44-53. doi: http://dx.doi.org/10.1016/j.expneurol.2016.10.013.

Calvez, J., de Ávila, C., Guèvremont, G., & Timofeeva, E. (2016). Sex-specific effects of chronic administration of relaxin-3 on food intake, body weight and hypothalamo-pituitary-gonadal axis in rats. Journal of Neuroendocrinology, n/a-n/a. doi: 10.1111/jne.12439.

Haight, J. L., Fuller, Z. L., Fraser, K. M., & Flagel, S. B. (2016). A food-predictive cue attributed with incentive salience engages subcortical afferents and efferents of the paraventricular nucleus of the thalamus. Neuroscience. doi: http://dx.doi.org/10.1016/j.neuroscience.2016.10.043.

He, H., Guo, W.-W., Xu, R.-R., Chen, X.-Q., Zhang, N., Wu, X., & Wang, X.-M. (2016). Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide. BMC Complementary and Alternative Medicine, 16(1), 412. doi: 10.1186/s12906-016-1392-6.

Jin, T., Nicholls, F. J., Crum, W. R., Ghuman, H., Badylak, S. F., & Modo, M. (2017). Diamagnetic chemical exchange saturation transfer (diaCEST) affords magnetic resonance imaging of extracellular matrix hydrogel implantation in a rat model of stroke. Biomaterials, 113, 176-190. doi: http://dx.doi.org/10.1016/j.biomaterials.2016.10.043.

Kyyriäinen, J., Ekolle Ndode-Ekane, X., & Pitkänen, A. (2016). Dynamics of PDGFRβ expression in different cell types after brain injury. Glia, n/a-n/a. doi: 10.1002/glia.23094.

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MBF Bioscience Awarded Two Patents in 2016

InteractingWorms

We continue our history of innovation and invention as the U.S. Patent and Trademark Office awards us two patents. The first is for WormLab – our unique worm tracking software that gives researchers an enormous amount of behavioral data about a single worm or multiple worms, even as they go through omega bends, reversals, and entanglements. The second is for our radial shock wave technology that improves antibody penetration and reduces the time for antibody incubation and fixation periods.

WormLab is commercially available, while our shock wave technology is in development.

+ Learn more about WormLab

+ Read the WormLab patent

Read the shock wave patent

Researchers cited MBF systems in 18 papers during the week of 4/4/2016

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a Dzaye, O. D., Hu, F., Derkow, K., Haage, V., Euskirchen, P., Harms, C., . . . Kettenmann, H. (2016). Glioma Stem Cells but Not Bulk Glioma Cells Upregulate IL-6 Secretion in Microglia/Brain Macrophages via Toll-like Receptor 4 Signaling. Journal of Neuropathology and Experimental Neurology.

Kadoya, K., Lu, P., Nguyen, K., Lee-Kubli, C., Kumamaru, H., Yao, L., . . . Tuszynski, M. H. (2016). Spinal cord reconstitution with homologous neural grafts enables robust corticospinal regeneration. Nature Medicine, advance online publication. doi: 10.1038/nm.4066

Kneynsberg, A., Collier, T. J., Manfredsson, F. P., & Kanaan, N. M. (2016). Quantitative and semi-quantitative measurements of axonal degeneration in tissue and primary neuron cultures. Journal of Neuroscience Methods, 266, 32-41. doi: http://dx.doi.org/10.1016/j.jneumeth.2016.03.004.

Köse, O., Arabacı, T., Gedikli, S., Eminoglu, D. Ö., Kermen, E., Kızıldağ, A., . . . Yemenoglu, H. (2016). Biochemical and histopathologic analysis of the effects of periodontitis on left ventricular heart tissues of rats. Journal of Periodontal Research, n/a-n/a. doi: 10.1111/jre.12380.

Mohanty, R., Das, S. k., Singh, N. R., & Patri, M. (2016). Withania somnifera Leaf Extract Ameliorates Benzo[a]pyrene-Induced Behavioral and Neuromorphological Alterations by Improving Brain Antioxidant Status in Zebrafish (Danio rerio). Zebrafish. doi: 10.1089/zeb.2015.1215.

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Researchers cited MBF systems in 17 papers during the week of 3/21/2016

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Avsar, U., Halici, Z., Akpinar, E., Yayla, M., Harun, U., Hasan, T. A., & Bayraktutan, Z. (2016). The Effects of Argan Oil in Second-degree Burn Wound Healing in Rats. Ostomy/Wound Management, 62(3), 26.

Boschen, K. E., Ruggiero, M. J., & Klintsova, A. Y. (2016). Neonatal binge alcohol exposure increases microglial activation in the developing rat hippocampus. Neuroscience. doi:http://dx.doi.org/10.1016/j.neuroscience.2016.03.033.

Chu, Y., Morfini, G. A., & Kordower, J. H. (2016). Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson’s Disease. Journal of Parkinson’s Disease(Preprint), 1-21.

Ghuman, H., Massensini, A. R., Donnelly, J., Kim, S.-M., Medberry, C. J., Badylak, S. F., & Modo, M. (2016). ECM hydrogel for the treatment of stroke: Characterization of the host cell infiltrate. Biomaterials. doi:http://dx.doi.org/10.1016/j.biomaterials.2016.03.014.

Guardia Clausi, M., & Levison, S. W. (2016). Delayed ALK5 inhibition improves functional recovery in neonatal brain injury. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678×16638669.

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Researchers cited MBF systems in 19 papers during the week of 10/26/2015

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Bernstock, J. D., Lee, Y.-j., Peruzzotti-Jametti, L., Southall, N., Johnson, K. R., Maric, D., . . . Hallenbeck, J. M. (2015). A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678×15609939.

Haeussner, E., Aschauer, B., Burton, G. J., Huppertz, B., Edler von Koch, F., Müller-Starck, J., . . . Frank, H.-G. (2015). Does 2D-Histologic identification of villous types of human placentas at birth enable sensitive and reliable interpretation of 3D structure? Placenta. doi: http://dx.doi.org/10.1016/j.placenta.2015.10.003.

Kumar, A., Alvarez-Croda, D.-M., Stoica, B. A., Faden, A. I., & Loane, D. J. (2015). Microglial/macrophage polarization dynamics following traumatic brain injury. Journal of Neurotrauma. doi: 10.1089/neu.2015.4268.

Nam, J. H., Park, E. S., Won, S.-Y., Lee, Y. A., Kim, K. I., Jeong, J. Y., . . . Jin, B. K. (2015). TRPV1 on astrocytes rescues nigral dopamine neurons in Parkinson’s disease via CNTF. [10.1093/brain/awv297]. Brain.

Peck, J. D., Quaas, A. M., Craig, L. B., Soules, M. R., Klein, N. A., & Hansen, K. R. (2015). Lifestyle factors associated with histologically derived human ovarian non-growing follicle count in reproductive age women. Human Reproduction. doi: 10.1093/humrep/dev271.

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Researchers cited MBF systems in 15 papers during the week of 10/19/2015

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Bingol, F., Yoruk, O., Bingol, B. O., Erdemci, B., Ozkan, O., & Mazlumoglu, M. R. (2015). Estimation of the efficacy of chemo-radiotherapy on tumor regression in the patients with laryngeal cancer via computerized tomography using the Cavalieri method. Acta Oto-Laryngologica, 1-4. doi: 10.3109/00016489.2015.1096958.

Darlot, F., Moro, C., El Massri, N., Chabrol, C., Johnstone, D. M., Reinhart, F., . . . Benabid, A.-L. (2015). Near-infrared light is neuroprotective in a monkey model of Parkinson’s disease. Annals of Neurology, n/a-n/a. doi: 10.1002/ana.24542.

McConnell, E. D., Wei, H. S., Reitz, K. M., Kang, H., Takano, T., Vates, G. E., & Nedergaard, M. (2015). Cerebral microcirculatory failure after subarachnoid hemorrhage is reversed by hyaluronidase. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678×15608389.

Prokop, S., Miller, K. R., Drost, N., Handrick, S., Mathur, V., Luo, J., . . . Heppner, F. L. (2015). Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer’s disease–like mice. The Journal of Experimental Medicine, 212(11), 1811-1818. doi: 10.1084/jem.20150479.

Rocha, M. C., Grady, J. P., Grünewald, A., Vincent, A., Dobson, P. F., Taylor, R. W., . . . Rygiel, K. A. (2015). A novel immunofluorescent assay to investigate oxidative phosphorylation deficiency in mitochondrial myopathy: understanding mechanisms and improving diagnosis. Scientific Reports, 5, 15037. doi: 10.1038/srep15037

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