Alzheimer's disease is the most common form of dementia. Most cases occur in people over 65, and are not genetically inherited. Roughly five percent of Alzheimer's patients suffer from familial Alzheimer's disease (FAD), an uncommon form that tends to strike sooner, and is related to a genetic predisposition - most commonly, a mutation in the presenilin 1 gene (PS1). A recent study, led by Dr. Miguel...
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Thousands of people in the United States have spinal cord injuries (SCIs), with associated loss of movement and sensation below the site of the injury. Neural and glial cell transplants into research animals after SCI have correlated with recovery of function. The improvement may be caused by the transplanted cells; it’s thought that remyelination by the transplanted glial cells is the main reason for the...
Read More We continue to take an active role in assisting researchers become proficient in design-based stereology with this publication. It is intended to introduce the methodology to scientists who are interested in, but not familiar with, its application in neuroscience and other biomedical research fields. A concise, accessible book, this text is an excellent first resource for scientists. Available at amazon.com or by contacting MBF Bioscience. ...
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Stereo Investigator Pulmonary Edition, our latest stereology software solution, is designed specifically to assist pulmonary researchers with quantitative stereological analysis. Stereo Investigator Pulmonary Edition introduces the Connectivity Assay. Using live video superimposed over captured images, pulmonary researchers can quickly mark bridges and islands. "Whether you’re counting alveoli or quantifying cells, lengths, or volumes, Stereo Investigator Pulmonary Edition’s intuitive workflow technology simplifies stereology," said MBF Bioscience President...
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Stereology allows us to estimate the amount and size of biological features that are impossible or prohibitive to measure exhaustively. If the stereological probe is designed well, and we can manage to follow all the rules, bias due to sampling design and estimation methods will be eliminated, resulting in a more accurate estimate. For instance, when using the Optical Fractionator to estimate the number of cells...
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