Dr. Bob Jacobs has traced his 5,000th and final neuron. “It’s a good stopping point I think,” says the long-time MBF Bioscience customer, collaborator, and friend, who is retiring from research in December. Dr. Jacobs has made significant advances in the fields of neuroanatomy and neuroethology over the course of his 30-year career. And the team at MBF Bioscience is grateful for the collaborative relationship we’ve...
Read More
Researchers at Colorado College may have identified a new neuropathological hallmark of Chronic Traumatic Encephalopathy (CTE). Their findings, published in the Journal of Comparative Neurology, describe overall dendritic atrophy across cortical neurons and greater morphological variability in CTE brains compared to controls. A neurodegenerative disorder characterized by late-onset symptoms like depression, confusion, and memory loss, CTE is caused by repeated impacts to the brain. The disease...
Read More
For Immediate Release: Williston, VT — October 6, 2020 — Big science produces big data. At laboratories around the world, researchers from every scientific discipline face a similar problem — how to manage the massive image files generated by large-scale experimental imaging workflows. MBF Bioscience has solved this problem by leveraging our scientific imaging expertise to produce MicroFile+, a freely available software tool for the scientific community....
Read More
For Immediate Release: Williston, VT (September 25, 2020)—To support the scientific community’s movement toward a more open and collaborative climate, MBF Bioscience is making their digital reconstruction file format, the Neuromorpholocial File Specification open and available to all researchers. MBF Bioscience has a long history of supporting openness and collaboration in neuroscience research. MBF Bioscience’s file format has evolved for over 30 years, influenced by leading neuroscientists,...
Read More
Scientists at Western Sydney University used Stereo Investigator and Neurolucida 360 to quantify cells in a mouse model of neuroinflammation after feeding mice two different curcumin formulations. Some inflammation is normal in a healthy mammalian brain. But as the brain ages, processes can break down, leading to chronic neuroinflammation. This can develop into Alzheimer’s disease, dementia, and other neurodegenerative diseases. Scientists at Prof. Gerald Muench’s lab, at...
Read More
MBF Bioscience was just awarded a patent by the USPTO for our new brain mapping technology! This novel technology is now available in our BrainMaker and NeuroInfo software to map image data and all associated measurements into a common coordinate system so that data can be compared across animals, cohorts, and laboratories. Learn more about NeuroInfo at https://www.mbfbioscience.com/neuroinfo ...
Read More
Biolucida for Medical Education is a learning platform that serves high resolution microscope slides to students without the need for a physical microscope. As universities around the world move to online classes during the COVID-19 pandemic, educators suddenly need to find ways to create authentic learning experiences for their students. Biolucida for Medical Education creates that experience by giving students studying at home the same experience...
Read More
An interdisciplinary team of researchers, including MBF Bioscience’s Dr. Susan Tappan and Maci Heal, have created a fully reconstructed, virtual 3D heart, digitally showcasing the heart's unique network of neurons for the first time. The investigators in this study--appearing May 26 in the journal iScience--created a comprehensive map of the intrinsic cardiac nervous system at a cellular scale using MBF Bioscience’s Tissue Mapper and TissueMaker software....
Read More
Neurolucida 360 Used to Analyze Dendrites and Dendritic Spines Amyloid plaques and tau tangles are the hallmarks of Alzheimer’s disease (AD) pathology, but synapse loss is what causes cognitive decline, scientists say. In a paper published in Science Signaling, researchers at the Herskowitz Lab, at the University of Alabama at Birmingham, used Neurolucida 360 to analyze spine density and dendritic length in hAPP mice — a...
Read More
For Immediate Release: Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard for microscopic imaging. The new decade is poised to bring about incredible scientific innovations, and MBF Bioscience is leading the charge in 2020 with the creation of the “light sheet theta microscope” system, ClearScope. MBF Bioscience secured exclusive license from Columbia University to develop the light...
Read More