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Scientific Applications & Use Cases

MBF Bioscience >  Blog > Scientific Applications & Use Cases (Page 3)
December 10, 2020

MBF Bioscience Release ClearScope, Revolutionary Light Sheet Microscope for Imaging Large and Small Cleared Tissue Specimens

by Pasang
in Company News, ClearScope®, Press Release, Scientific Applications & Use Cases, MBF Products & Service Solutions, Microscopy Imaging Systems, Cleared Tissue and Whole Organ Research, Additional Subject Matter, Light Sheet
Comments

For Immediate Release  Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D.     The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...

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This is an image of a full Light Sheet Microscope called ClearScope
February 4, 2020

MBF Bioscience Secures Exclusive License from Columbia University to Create New Light-Sheet Microscope System

by Pasang
in Company News, ClearScope®, Press Release, Scientific Applications & Use Cases, MBF Products & Service Solutions, Microscopy Imaging Systems, Additional Subject Matter, Cleared Tissue and Whole Organ Research, Light Sheet
Comments

For Immediate Release: Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard for microscopic imaging.   The new decade is poised to bring about incredible scientific innovations, and MBF Bioscience is leading the charge in 2020 with the creation of the “light sheet theta microscope” system, ClearScope.   MBF Bioscience secured exclusive license from Columbia University to develop the light...

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September 5, 2018

MBF Bioscience’s New Software Vesselucida 360 Reconstructs Microvascular Networks in 3D

by Pasang
in Software Applications For Quantitive Analysis, Company News, Press Release, MBF Products & Service Solutions, Additional Subject Matter, 3D Reconstruction, Vesselucida®360, Vesselucida®Explorer, Microvessel Imaging & Analysis
Comments

Williston, VT – September 5, 2018 – Researchers studying microvascular networks and vessels have a groundbreaking new software application to facilitate their work. Developed by MBF Bioscience, Vesselucida®360 automatically reconstructs and analyzes microvascular networks in 3D.   Specifically designed to recognize the intricacies of the vascular system, Vesselucida features sophisticated algorithms that quickly and accurately create 3D reconstructions of images and tissue specimens. Built-in analyses provide data...

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June 29, 2018

MBF Bioscience Launches Stereo Investigator Whole Slide Edition for Quantitative Analysis of Whole Slide Image Data

by Pasang
in Software Applications For Quantitive Analysis, Company News, Scientific Applications & Use Cases, Press Release, MBF Products & Service Solutions, Additional Subject Matter, Whole Slide Imaging & Analysis, Software
Comments

Williston, VT – June 29, 2018 – MBF Bioscience is pleased to announce the launch of the Whole Slide Edition of Stereo Investigator. This is a new version of our renown Stereo Investigator software, designed especially for conducting stereology on images from slide scanners.   Featuring a streamlined, user-friendly interface, this new product includes a variety of probes for quantifying number, length, volume, and surface area of...

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January 16, 2018

American Association of Anatomists Launches Virtual Microscopy Database powered by Biolucida

by Pasang
in Biolucida, Company News, Scientific Applications & Use Cases, Press Release, MBF Products & Service Solutions, Additional Subject Matter, Big Image Data Management Solutions, Medical Education
Comments

Free resource for educators and researchers features thousands of downloadable histology slides   Educators and researchers around the world now have free access to a database of whole slide images (also known as virtual slides) for histology and pathology. Featuring thousands of virtual slides contributed by 15 universities, The Virtual Microscopy Database, VMD, (http://www.virtualmicroscopydatabase.org/) is an online resource that allows educators to view and download virtual images...

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November 30, 2017

NeuroMorpho.Org Releases Nearly 10,000 New Neuron Reconstructions and Neurolucida leads the way

by Pasang
in Software Applications For Quantitive Analysis, Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, MBF Products & Service Solutions, Neurolucida®360, 3D Reconstruction, Neuron Reconstruction
Comments

[caption id="attachment_6839" align="aligncenter" width="632"] Image Courtesy: Bob Jacobs, Ph.D. , Colorado College[/caption]   With the release of its new version on November 28, NeuroMorpho.org adds 9,987 new images to its archive, bringing its impressive collection of digitally reconstructed neurons to 80,012.   Scientists used MBF Bioscience’s software, Neurolucida and Neurolucida 360, to reconstruct the majority of these cells. In fact, 64 times more neurons were reconstructed with MBF Bioscience...

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November 7, 2017

MBF Bioscience unveils whole mouse brain automatic region delineation and cell mapping with the Allen Mouse Brain Reference Atlas

by Pasang
in Biolucida, Company News, Neurolucida®, Software Applications For Quantitive Analysis, Stereo Investigator®, Software & Microscope Integrated Systems, Scientific Applications & Use Cases, Artificial Intelligence, MBF Products & Service Solutions, Big Image Data Management Solutions, NeuroInfo®, Additional Subject Matter, 3D Reconstruction
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  Analyzing cellular populations within specific anatomies in brain images requires expertise in both neuroanatomy and cellular identification. This typically involves a scientist comparing experimental images with a reference atlas and manually delineating anatomical regions and marking cell populations within. NeuroInfo®, a revolutionary new technology from MBF Bioscience, enables researchers to automatically identify and delineate mouse brain regions based on the publicly available Allen Mouse Brain...

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September 26, 2017

Diet Restriction Slows Neurodegeneration and Extends Lifespan of DNA-Repair-Deficient Mice

by Pasang
in Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Stereology
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  DNA damage occurs in human cells at a constant rate. These cells are usually able to repair themselves, but sometimes deficiencies in certain genes cause the repair process to shut down. When damaged DNA isn't fixed, mutations can occur that cause accelerated aging or cancerous tumors to form (Hoeijmakers, 2009). Scientists at Erasmus University Medical Center in Rotterdam have found a way to slow down...

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March 24, 2017

A complete guide to imaging and analyzing spines and neurons with Neurolucida 360

by Pasang
in Software Applications For Quantitive Analysis, Scientific Applications & Use Cases, MBF Products & Service Solutions, Additional Subject Matter, Neurolucida®360, 3D Reconstruction, Neuron Reconstruction
Comments

Following a well-designed protocol is essential to achieving accurate and consistent results in scientific research. Now, scientists using Neurolucida 360 for dendritic spine and neuron analysis can follow a published set of guidelines to ensure optimal confocal data series for proper dendritic spine quantification and neuron reconstruction. The paper, written by MBF Bioscience scientists and researchers from the Icahn School of Medicine at Mount Sinai...

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January 11, 2017

Uncovering the role of microglia in fetal alcohol spectrum disorders

by Pasang
in Neurolucida®, Scientific Applications & Use Cases, Software & Microscope Integrated Systems, Stereo Investigator®, MBF Products & Service Solutions, Stereology, Neuron Reconstruction
Comments

[caption id="attachment_6526" align="aligncenter" width="800"] Representative images of Iba-1+ microglia in the postnatal day 10 rat hippocampus. Image courtesy of Anna Klintsova, PhD.[/caption] Children born with fetal alcohol spectrum disorders face a range of physical and cognitive impairments including long-term deficits in learning, behavior, and immune function. In a paper published in Neuroscience, Dr. Anna Klintsova and her lab at the University of Delaware report that activation...

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