Researchers cited MBF systems in 20 papers during the week of 6/20/2016

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Bilella, A., Alvarez-Bolado, G., & Celio, M. R. (2016). The Foxb1-expressing neurons of the ventrolateral hypothalamic parvafox nucleus project to defensive circuits. Journal of Comparative Neurology, n/a-n/a. doi: 10.1002/cne.24057.

Cvetanovic, M., Hu, Y.-S., & Opal, P. (2016). Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1.  The Cerebellum, 1-8. doi: 10.1007/s12311-016-0794-9.

Delpech, J.-C., Wei, L., Hao, J., Yu, X., Madore, C., Butovsky, O., & Kaffman, A. (2016). Early life stress perturbs the maturation of microglia in the developing hippocampus. Brain, Behavior, and Immunity. doi:http://dx.doi.org/10.1016/j.bbi.2016.06.006.

Herring, A., Münster, Y., Akkaya, T., Moghaddam, S., Deinsberger, K., Meyer, J., . . . Keyvani, K. (2016). Kallikrein-8 inhibition attenuates Alzheimer’s pathology in mice. Alzheimer’s & Dementia. doi:http://dx.doi.org/10.1016/j.jalz.2016.05.006.

Herring, A., Münster, Y., Metzdorf, J., Bolczek, B., Krüssel, S., Krieter, D., . . . Keyvani, K. (2016). Late running is not too late against Alzheimer’s pathology. Neurobiology of Disease, 94, 44-54. doi:http://dx.doi.org/10.1016/j.nbd.2016.06.003.

Madhavadas, S., & Subramanian, S. (2016). Cognition enhancing effect of the aqueous extract of Cinnamomum zeylanicum on non-transgenic Alzheimer’s disease rat model: Biochemical, histological, and behavioural studies. Nutritional Neuroscience, 1-12.

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Researchers cited MBF systems in 11 papers during the week of 6/6/2016

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Aghoghovwia, B. E., & Oorschot, D. E. (2016). Absolute number of parvicellular and magnocellular neurons in the red nucleus of the rat midbrain: a stereological study. Journal of Anatomy, n/a-n/a. doi: 10.1111/joa.12495.

Mehta, P., Premkumar, B., & Morris, R. (2016). Production of high quality brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) RNA from isolated populations of rat spinal cord motor neurons obtained by Laser Capture Microdissection (LCM). Neuroscience Letters. doi:http://dx.doi.org/10.1016/j.neulet.2016.05.063.

Rau, K. K., Hill, C. E., Harrison, B. J., Venkat, G., Koenig, H. M., Cook, S. B., . . . Petruska, J. C. (2016). Cutaneous tissue damage induces long-lasting nociceptive sensitization and regulation of cellular stress- and nerve injury-associated genes in sensory neurons. Experimental Neurology. doi:http://dx.doi.org/10.1016/j.expneurol.2016.06.002.

Singh-Bains, M. K., Tippett, L. J., Hogg, V. M., Synek, B. J., Roxburgh, R. H., Waldvogel, H. J., & Faull, R. L. M. (2016). Globus pallidus degeneration and clinico-pathological features of Huntington’s disease. Annals of Neurology, n/a-n/a. doi: 10.1002/ana.24694.

Sturm, E., Fellner, L., Krismer, F., Poewe, W., Wenning, G. K., & Stefanova, N. (2016). Neuroprotection by Epigenetic Modulation in a Transgenic Model of Multiple System Atrophy.. Neurotherapeutics, 1-9. doi: 10.1007/s13311-016-0447-1.

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Researchers cited MBF systems in 15 papers between 5/20/2016 and 6/3/2016

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Acabchuk, R., Briggs, D. I., Angoa-Pérez, M., Powers, M., Wolferz, R., Soloway, M., . . . Conover, J. C. (2016). Repeated mild traumatic brain injury causes focal response in lateral septum and hippocampus. Concussion. doi: 10.2217/cnc-2015-0001.

Gully, J. C., Sergeyev, V. G., Bhootada, Y., Mendez-Gomez, H., Meyers, C. A., Zolotukhin, S., . . . Gorbatyuk, O. S. (2016). Up-regulation of activating transcription factor 4 induces severe loss of dopamine nigral neurons in a rat model of Parkinson’s disease. Neuroscience Letters. doi: http://dx.doi.org/10.1016/j.neulet.2016.05.039.

Hendrikx, G., Vries, M. H., Bauwens, M., De Saint-Hubert, M., Wagenaar, A., Guillaume, J., . . . Mottaghy, F. M. (2016). Comparison of LDPI to SPECT perfusion imaging using 99mTc-sestamibi and 99mTc-pyrophosphate in a murine ischemic hind limb model of neovascularization. EJNMMI Research, 6(1), 1-10. doi: 10.1186/s13550-016-0199-2.

Mangus, L. M., Dorsey, J. L., Weinberg, R. L., Ebenezer, G. J., Hauer, P., Laast, V. A., & Mankowski, J. L. (2016). Tracking Epidermal Nerve Fiber Changes in Asian Macaques: Tools and Techniques for Quantitative Assessment. Toxicologic Pathology. doi: 10.1177/0192623316650286.

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Researchers cited MBF systems in 12 papers during the week of 5/16/2016

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Kim, B.-W., Jeong, K. H., Kim, J.-H., Jin, M., Kim, J.-H., Lee, M.-G., . . . Jeon, M.-T. (2016). Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System. The Journal of Neuroscience, 36(20), 5608-5622.

Kobro-Flatmoen, A., Nagelhus, A., & Witter, M. P. (2016). Reelin-immunoreactive neurons in entorhinal cortex layer II selectively express intracellular amyloid in early Alzheimer’s disease. Neurobiology of Disease, 93, 172-183. doi: http://dx.doi.org/10.1016/j.nbd.2016.05.012.

Li, A., Nattie, E., & Roy, S. (2016). The Enhanced CO2 Chemoreflex is Associated with Increased Number of CO2-activated Orexin Neurons in the Lateral Hypothalamus in Spontaneously Hypertensive Rats (SHRs). The FASEB Journal, 30(1 Supplement), 772.777.

Lindquist, R. A., Guinto, C. D., Rodas-Rodriguez, J. L., Fuentealba, L. C., Tate, M. C., Rowitch, D. H., & Alvarez-Buylla, A. (2016). Identification of proliferative progenitors associated with prominent postnatal growth of the pons. Nat Commun, 7. doi: 10.1038/ncomms11628.

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Neurolucida 360 v2.7: A minor release with major new features

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The 3 algorithms in Neurolucida 360 were used in combination
to create a smooth, accurate reconstruction

Minor releases typically don’t include new features, but Neurolucida 360 isn’t an ordinary piece of software. Neurolucida 360 v2.7 has many new features and improvements including:

  • A new automatic tracing algorithm – Rayburst Crawl
  • Capture videos of your rotating neuron reconstructions for presentations and publications
  • New backbone length analysis for dendritic spines
  • Improved handling of images exceeding 10GB

With the addition of Rayburst Crawl, Neurolucida 360 now has 3 different algorithms for automatic neuron reconstruction. Why 3 algorithms? To give you the power to choose the one that works best with your images. Labeling specificity, staining intensity, and image signal-to-noise can vary widely within a specimen – making it impossible for a single tracing algorithm to work optimally in all situations.

If you want more control over your neuron reconstructions, the same 3 algorithms can be used in user-guided mode. You follow a dendritic branch or axon with your mouse cursor and the algorithm finds the center and thickness of the process. It combines the unrivaled human ability to identify and segment objects with the speed of a computer.

Try it for yourself.

Request a free trial to see the algorithms in action

Or, if you are a customer with an up to date support subscription, download version 2.7

 

MBF Bioscience to Open European Headquarters in the Netherlands

Mbf Bioscience Europe

MBF Bioscience announced today that it will open a European Sales and Support office in Delft, the Netherlands. Masha Stern, who has been the Manager of Technical Support and Training at MBF Bioscience headquarters in Vermont for 11 years, will become the Managing Director of MBF Europe. The new office is scheduled to open September 2016.

“Our new European Office is a result of the continually increasing demand for our products in Europe,” says Jack Glaser, President of MBF Bioscience. “Our new office in the Netherlands will allow us to better serve our growing customer base in Europe. Masha Stern’s long-term experience in managing and supporting our products will provide our European customers with a source of significant expertise and dedicated support and sales information for our products.”

“I’m very excited to lead our European operations and to represent our award-winning technology in Europe,” said Masha.

Delft is home to the prestigious Delft University of Technology and is the birthplace of Antonie Philips van Leeuwenhoek, the “Father of Microbiology” and developer of high-quality, high magnification microscope lenses.

Contact Masha at MBF Bioscience Europe: masha@mbfbioscience.com.

 

About MBF Bioscience

MBF Bioscience helps life science researchers collect accurate, reliable data from tissue specimens. Founded in 1987 by the current president, Jack Glaser, and his father, Edmund Glaser, MBF Bioscience systems are used in over 1,000 labs worldwide and have been cited in more than 10,000 research papers. MBF Bioscience received a Tibbetts award from the U.S. Small Business Association in recognition of their contributions to technological innovation and service to federal research and development.

Researchers cited MBF systems in 22 papers during the week of 5/9/2016

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García-Lezana, T., Oria, M., Romero-Giménez, J., Bové, J., Vila, M., Genescà, J., . . . Cordoba, J. (2016). Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy. Journal of Cerebral Blood Flow and Metabolism. doi: 10.1177/0271678×16649196.

Gordon, R., Singh, N., Lawana, V., Ghosh, A., Harischandra, D. S., Jin, H., . . . Kanthasamy, A. (2016). Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson’s disease. Neurobiology of Disease. doi:http://dx.doi.org/10.1016/j.nbd.2016.04.008.

Huttenrauch, M., Brausz, A., Kurdakova, A., Borgers, H., Klinker, F., Liebetanz, D., . . . Wirths, O. (2016). Physical activity delays hippocampal neurodegeneration and rescues memory deficits in an Alzheimer disease mouse model. Transl Psychiatry, 6, e800. doi: 10.1038/tp.2016.65.

K.G, B., G, M.-N., & H, G. (2016). Early life stress accelerates behavioral and neural maturation of the hippocampus in male mice. Hormones and Behavior. doi: http://dx.doi.org/10.1016/j.yhbeh.2016.04.010.

Larpthaveesarp, A., Georgevits, M., Ferriero, D. M., & Gonzalez, F. F. (2016). Delayed erythropoietin therapy improves histological and behavioral outcomes after transient neonatal stroke. Neurobiology of Disease, 93, 57-63. doi: http://dx.doi.org/10.1016/j.nbd.2016.04.006.

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Researchers cited MBF systems in 10 papers during the week of 5/2/2016

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Aytan, N., Choi, J.-K., Carreras, I., Brinkmann, V., Kowall, N. W., Jenkins, B. G., & Dedeoglu, A. (2016). Fingolimod modulates multiple neuroinflammatory markers in a mouse model of Alzheimer’s disease. Scientific Reports, 6, 24939. doi: 10.1038/srep24939.

Helseth, A., Adil, S., Linabarger, M., Arehart, E., Fainberg, N., Singh, D., . . . Mikati, M. (2016). Novel Knock-in Mouse Model of Genetic Atp1a3 Dysfunction (S52. 006). Neurology, 86(16 Supplement), S52. 006.

Li, Y., Stockton, M. E., Bhuiyan, I., Eisinger, B. E., Gao, Y., Miller, J. L., . . . Zhao, X. (2016). MDM2 inhibition rescues neurogenic and cognitive deficits in a mouse model of fragile X syndrome. [10.1126/scitranslmed.aad9370]. Science translational medicine, 8(336), 336ra361-336ra361.

Lim, D. C., Brady, D. C., Soans, R., Kim, E. Y., Valverde, L., Keenan, B. T., . . . Pack, A. I. (2016). Different Cyclical Intermittent Hypoxia Severities have Different Effects on Hippocampal Microvasculature. [10.1152/japplphysiol.01040.2015]. Journal of Applied Physiology.

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Researchers cited MBF systems in 18 papers during the week of 4/25/2016

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Drzewiecki, C. M., Willing, J., & Juraska, J. M. (2016). Synaptic number changes in the medial prefrontal cortex across adolescence in male and female rats: A role for pubertal onset. Synapse, n/a-n/a. doi: 10.1002/syn.21909.

Inoue, T., Abe, C., Sung, S.-s. J., Moscalu, S., Jankowski, J., Huang, L., . . . Okusa, M. D. (2016). Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes. The Journal of Clinical Investigation, 126(5). doi: 10.1172/jci83658.

Miller, A. N., Deal, D., Green, J., Houle, T., Brown, W., Thore, C., . . . Webb, L. X. (2016). Use of the Reamer/Irrigator/Aspirator Decreases Carotid and Cranial Embolic Events in a Canine Model. The Journal of Bone & Joint Surgery, 98(8), 658-664.

Ouda, L., Jílek, M., & Syka, J. (2016). Expression of c-Fos in rat auditory and limbic systems following 22-kHz calls. Behavioural Brain Research, 308, 196-204. doi: http://dx.doi.org/10.1016/j.bbr.2016.04.030.

Pantazopoulos, H., Wiseman, J. T., Markota, M., Ehrenfeld, L., & Berretta, S. (2016). Decreased numbers of somatostatin-expressing neurons in the amygdala of subjects with bipolar disorder or schizophrenia: Relationship to circadian rhythms. Biological Psychiatry. doi: http://dx.doi.org/10.1016/j.biopsych.2016.04.006.

Scheinert, R. B., Haeri, M. H., Lehmann, M. L., & Herkenham, M. (2016). Therapeutic effects of stress-programmed lymphocytes transferred to chronically stressed mice. Progress in Neuro-Psychopharmacology and Biological Psychiatry. doi: http://dx.doi.org/10.1016/j.pnpbp.2016.04.010.

Türer, A., Coşkun Türer, Ç., Durmuşlar, M. C., Balli, U., & Önger, M. E. (2016). The influence of oral administration of rosuvastatin on calvarial bone healing in rats. Journal of Cranio-Maxillofacial Surgery. doi:http://dx.doi.org/10.1016/j.jcms.2016.04.021. Continue reading “Researchers cited MBF systems in 18 papers during the week of 4/25/2016” »

MBF Bioscience Awarded Two Patents in 2016

InteractingWorms

We continue our history of innovation and invention as the U.S. Patent and Trademark Office awards us two patents. The first is for WormLab – our unique worm tracking software that gives researchers an enormous amount of behavioral data about a single worm or multiple worms, even as they go through omega bends, reversals, and entanglements. The second is for our radial shock wave technology that improves antibody penetration and reduces the time for antibody incubation and fixation periods.

WormLab is commercially available, while our shock wave technology is in development.

+ Learn more about WormLab

+ Read the WormLab patent

Read the shock wave patent