Pereda-Pérez I, Popović N, Otalora BB, Popović M, Madrid JA, Rol MA, Venero C.
Prolonged social isolation selectively impairs hippocampus-dependent contextual fear memory. This effect is associated with CA1 shrinkage and reduced synaptic PSA-NCAM expression. ... Read More
Kriks, S., Shim, JW., Piao, J. et al.
Floor plate–derived human dopamine neurons show robust survival and functional integration after transplantation. This approach advances stem cell–based therapy for Parkinson’s disease. ... Read More
Schmitz, Christoph et al
Hippocampal neuron loss occurs in APP/PS-1 transgenic mice independent of local amyloid plaque burden. These findings indicate that non–plaque-related mechanisms contribute to neurodegeneration in Alzheimer’s disease. ... Read More
Stranahan AM, Jiam NT, Spiegel AM, Gallagher M.
Aging leads to significant loss of both principal neurons and inhibitory interneurons in the dorsal prefrontal cortex. In contrast, ventral prefrontal regions remain structurally preserved.... Read More
Rapp PR, Gallagher M.
Unbiased stereological analysis reveals no neuron loss in hippocampal subfields of aged rats with memory deficits.... Read More