Leiwe MN, Fujimoto S, Baba T, Moriyasu D, Saha B, Sakaguchi R, Inagaki S, Imai T.
Seven-colour Tetbow labelling paired with QDyeFinder’s hue-based clustering allowed accurate assignment of neurite fragments to their parent neurons, surpassing conventional multicolour methods. Automated tracing and colour-vector analysis reconstructed complex morphologies across multiple sections.... Read More
Zhang Y, Bizanti A, Harden SW, Chen J, Bendowski K, Hoover DB, Gozal D, Shivkumar K, Heal M, Tappan S, Cheng ZJ.
Sympathetic catecholaminergic innervation of the mouse atria exhibited pronounced regional specialization, with highest axon density around the sinoatrial node and pulmonary vein junction. Major TH-positive bundles followed reproducible entry paths and branching patterns, providing a quantitative topography of atrial sympathetic input.... Read More
Merino-Galán L, Zamarbide M, Belloso-Iguerategui A, Alonso-Moreno MC, Gago B, Reinares-Sebastián A, Blesa J, Dumitriu D, Quiroga-Varela A, Rodríguez-Oroz MC.
Early dopamine depletion disrupts striatal plasticity but elicits compensatory spine and dendritic remodeling in SPNs, supporting network resilience in premotor parkinsonism.... Read More
Földy C, Malenka RC, Südhof TC.
Dendritic spine density declined in AD but remained intact in cognitively resilient cases, and network analysis of synaptic proteomes highlighted TWF2 as a key determinant of thin spine length. CRISPR-mediated TWF2 enhancement selectively extended thin spines without altering their density.... Read More