Structured Illumination

Clearer images for more accurate results

Structured Illumination microscopy allows researchers to clearly visualize multiple labels and co-localization within a biological specimen without the need for a laser scanning confocal microscope. This technique involves inserting a slider into the light path of a fluorescence microscope which projects a grid onto a specimen. The grid moves to different locations and an image is captured at each location. The individual images are then combined to create a single high-resolution, high-contrast image free of gridlines and out-of-focus light.   

Clear, crisp images make it easier to identify and analyze an object of interest in your specimen, especially when tracing neurons in Neurolucida or performing stereology with Stereo Investigator.

Learn more about the Structured Illumination Module

Our Structured Illumination Module seamlessly integrates Stereo Investigator, Neurolucida or Microlucida software with structured illumination hardware such as the Zeiss ApoTome, Olympus DSU, or Qioptiq OptiGrid – turning your fluorescent microscope into a confocal microscope.

Professional Technical Support

When you call us you will speak with a person - not an automated system. Talk to us about your hardware, software, or experimental design questions. Our team includes Ph.D. neuroscientists and experts in microscopy, stereology, neuron tracing, and image processing; ready to help you over the phone or online.

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