Biolucida®for Research

Manage big image data
MBF Bioscience > Biolucida®for Research

Product Overview

Biolucida is a hub for 2D and 3D big image data. It stores all of your 2D and 3D image data and metadata in a secure, permanent location accessible via the web. Images can be acquired with slide scanners or microscope systems, and can be any size – Biolucida is built to store, organize, and serve huge image collections. The possibilities are endless with Biolucida: share images with collaborators, include large image sets from published papers, contribute standardized data to public image data repositories, or analyze images on any computer with Neurolucida 360, Stereo Investigator, BrainMaker. You will always have control over your images and access to them.

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Key Benefits

Biolucida allows researchers to share and standardize data via an intuitive yet powerful web interface. Create and share collections of annotated image data and control access with a few clicks. Content from previous research can also be included via image inclusion or simple HTML weblinks.

Biolucida easily integrates with an institute's IT architecture using secure and current standard web technologies. Biolucida utilizes extensive client and server optimizations to ensure the fastest image access experience, even at peak internet usage times.

System Requirements for Biolucida Viewer

Operating System

  • Windows 10, 64-bit
  • OSX 10.9 or later
RAM

At least 6 GB

System Requirements for Biolucida Server

Operating System

  • Linux (CentOS 6 or 7)
  • Windows server 2016 or later
Processor

minimum 4-cores for 2D/3D  whole slide images

RAM

minimum 8GB with connectivity of 1 Gbps or great

Biolucida exists as a standard, easily maintained WAMP/LAMP stack and proprietary C++ derived software.

MBF Bioscience Solves Your Big Data Challenges
>> Learn More

Mapping the Neurons of the Rat Heart in 3D
>> Learn More

American Association of Anatomists Launches Virtual Microscopy Database powered by Biolucida
>> Learn More

Medical Schools Take Learning Online with Biolucida During COVID-19
>> Learn More

Bringing Virtual Slides to the Medical Education Classroom with Biolucida Cloud 2.0
>> Learn More

 

Visit our blog to read more case studies

Download Biolucida for Research product sheet here.

 

Biolucida® Version 5.0 

New Features and Enhancements:

  • Images can now be viewed with any standard web browser using a new cross-platform HTML5 web viewer that doesn’t rely on Java or Flash. This feature can be enabled or disabled for any slide collection to control data access. Hyperlinks to images regions can also be shared and embedded within external documents and pages for integration with lab manuals and educational platforms.
  • GOTO functionality allows users to easily view and toggle annotations in slides from a clickable list.
  • Added a “Filmstrip” that shows and navigates individual planes for image stacks in the web viewer.
  • Added support for new whole slide image formats: Zeiss CZI, Olympus VSI, and BigTiff.
  • If given permission, users can upload slides and images from the Biolucida viewer or web browser directly to server.
  • If given permission, users can download full images from a Biolucida server to their local systems.
    New MBF built Jpeg2000 streaming technology with robust support for huge 3D slides viewed by large numbers of concurrent users.
  • New security framework for Biolucida server processes.
  • Added a new WAMP installer by MBF Bioscience with the most recent updated from Apache and PHP.
  • A new logging system with improved UI and use metrics added for administrators.
  • Viewer support for the latest operating systems (Windows 10, OSX 10.11 El Capitan, Linux CentOS 7)
  • Administrators can now view users’ access permissions for all slide collection in one table.
  • Support for all images formats served by Biolucida can be enabled or disabled by configurations on the server.
  • Slide collections can now be titled with descriptions. Descriptions live at the top of the slide collection and can contain experimental, case, and instructional information.
  • Search and navigation results are now presented instantly in a scrolling, rather than paged, format. Searches can also be restricted to specific slide collections, or performed across all slides a user has permission to view.
  • YouTube videos can now be viewed directly in the Biolucida Viewer.
  • Redesign of the image page and image edit interfaces.
  • Added the ability to show either filename or user specified image name for thumbnails.
  • Improved scrolling to accommodate large scale file, directory, and collection listings.

 

View Full Version History Here.

Who Is Using Biolucida?

More than 150,000 students have used Biolucida for Medical Education to study histology and histopathology

News About Biolucida

Cited in Peer Reviewed Scientific Publications

Biolucida’s utility is underscored by the number of references it receives in the worlds most important scientific publications.

Frequently Asked Questions (FAQ)

How does Biolucida work?

Biolucida consists of 3 parts: a server computer, Biolucida server software, and the Biolucida viewer. Together, the server computer and server software constitute a virtual central library where your slides are maintained and served. Biolucida can integrate into existing IT infrastructure, it can be set up in another location, or it can be hosted in the cloud with Amazon Web Services.


The Biolucida server software allows educators and students to navigate through large images quickly — there is no waiting for images to download. This
software runs behind the scenes and is not visible to users.


The viewer is the software application that instructors and students use to view, access, and share virtual slides. The viewer can run on any computer (PC or Mac) connected to the internet.

How large can the files be?

Biolucida efficiently serves very large virtual slides. A typical single image size is 10-50 gigabytes, but Biolucida can easily handle an image that exceeds of
terabytes.

Which computer platforms do you support?

The Biolucida viewer runs on Mac and PC, and the Biolucida server software runs on Windows and Linux. The Biolucida web browser viewer also allows viewing
slides on mobile platforms such as iPads.

Can I use images acquired with my slide scanner or my confocal microscope?

Yes, Biolucida supports images acquired with slide scanners from companies such as Huron, Aperio, Leica, Olympus, Zeiss and Hamamatsu. It also supports
images and image stacks acquired with confocal microscopes from companies such as Zeiss, Olympus, and Leica.

Can I easily compare images?

Yes, Biolucida lets you easily compare multiple images simultaneously.

Can I focus through 3D virtual slides?

Yes, Biolucida supports 3D virtual slides and allows users to focus through image planes just like a microscope.

Testimonials

Robust Professional Support

Our service sets us apart, with a team that includes Ph.D. neuroscientists, experts in microscopy, stereology, neuron tracing, and image processing.  We’ve also developed a host of additional support services, including:

  • Forums
    We have over 25 active forums where open discussions take place.
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  • On-Site/Training
    We’ve conducted over 750 remote software installations.
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  • Webinars
    We’ve created over 55 webinars that demonstrate our products & their uses.
    >> Learn More

Request an Expert Demonstration

We offer a free expert demonstration of Biolucida. During your demonstration you’ll also have the opportunity to talk to us about your hardware, software, or experimental design questions with our team of Ph.D. neuroscientists and experts in microscopy, neuron tracing, and image processing.

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Recorded Webinars and Videos

Webinar: Using Biolucida to Create Histology Classes from Whole Slide Images

Using Biolucida Cloud for Creating & Utilizing Educational Material for Medicine & Science

Exploring Big Data in Microscopy