What's new

New features and improvements in version 2025

See the current Release Notes or all Release Notes for Neurolucida 360.

  • New ability to create custom spine classifications to accommodate your specific research needs.

  • Large image- and data-file handling are now faster and more robust.

  • Added the ability to save a subvolume as a new image providing easier and more precise cropping.

  • Tracing speed has been improved with .jpx images that were converted from .czi format.

  • Updated the Attach marker to object 2D editing option for a more straight forward procedure.

  • Updated the 2D scale bar location options for more precise placement.

  • Improved the Measure Intensity tool image-handling capabilities for adjusting color-channel options for determining the average pixel intensity of modeled 3D structures or image data inside a drawn contour.

  • Improved image adjustment options for .oib images.

  • New automatic stitching of overlapping image tiles in the Montage tool is now available to optimize the visual information of compiled image montages.

  • Updated the Publish ribbon to include the Select Objects tool for easier access when editing scale bars, arrows, or text.

SPARC Users

The Stimulating Peripheral Activity to Relieve Conditions (SPARC) program seeks to accelerate development of therapeutic devices that modulate electrical activity in nerves to improve organ function.

  • Term import and search has been added to tree and vessel classification for easier navigation of the anatomical terminology list

Previous Releases

  • The Neurolucida 360 Ultra package is now available! It includes all of the advanced vascular modeling features from Vesselucida 360 and enables you to explore the intricate dynamics of neuronal and vascular interactions with a single software package.

    Learn more on our website or contact us for more information.

  • Update to offline software licensing. Due to updates to the Neurolucida 360 activation process, systems that that do not have access to the internet or have intermittent/unreliable internet access require reactivation. View instructions for offline software activation.

  • Improvements to the vessel tracing options in the 2D window.

  • Automove will now reposition focus when Continuous tracing is being used.

  • Color channel selection in puncta setup will begin at number 1.

  • Improvements to synchronization of contours delineated in 2D and 3D.

  • Image file paths are displayed in the Image Organizer.

  • New ability to display the 3D scale bar while recording a Movie.

  • New Puncta-detection user interface improves and expands capabilities for specifying puncta detection settings.

    • Detect puncta based on proximity to other structures, such as trees, spines, and varicosities using rule sets.

    • Employ powerful And/Or criteria in your rule sets to find specific puncta easily.

    • Save your settings and reuse your puncta-detection criteria for multiple images, including in the batch pipeline for processing entire directories of image data.

  • New image filters added to the batch process pipeline.

    • ExM image filter includes three options to use to optimize modeling of your expansion-microscopy images.

    • Tone Mapping image filter uses contrast adjustments to reveal details in both bright and dim regions of your image.

  • Improvements to the movie creation tool:

    • You can now generate movies at high resolution for large data sets.

    • Simple drag and drop to open.xml movie files.

    • Display the 3D scale bar while recording a Movie.

    • Change image-display settings for image slice and partial projections.

Previous Releases for SPARC users

  • SPARC vocabulary-term lists can now be displayed as ontological trees

  • New Import 3D Model tool for displaying generic SPARC organ scaffolds in the 3D environment

  • Network licensing is now available for SPARC researchers.
  • New Quick surface tool partially automates the process of creating contours to map interior and exterior surfaces.