BrightSLICE User Guide

Version 2025

Overview

The SLICE system offers the power of advanced light-sheet microscopy at a fraction of the cost of conventional systems. Projected light sheet microscopy (pLSM) is a cutting-edge imaging technique that uses dynamic, modulated light sheets for high resolution visualization of cleared samples. This innovative approach enables multi-resolution imaging, compatibility with a variety of clearing methods and minimal photobleaching making it particularly valuable for fields like developmental biology, neuroscience, and other areas requiring detailed analysis of cleared intact specimens. SLICE embodies these advancements, delivering a compact design and user-friendly interface that makes cutting-edge imaging technology accessible to labs of all sizes.