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	<title>Microscopy Imaging Systems Archives - MBF Bioscience</title>
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	<title>Microscopy Imaging Systems Archives - MBF Bioscience</title>
	<link>https://www.mbfbioscience.com/category/mbf-products-service-solutions/microscopy-imaging-systems/</link>
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	<item>
		<title>Breaking the size barrier: ClearScope light sheet microscope paper published in Journal of Imaging</title>
		<link>https://www.mbfbioscience.com/news/2026/03/clearscope-a-fully-integrated-light-sheet-theta-microscope-for-sub-micron-resolution-imaging</link>
					<comments>https://www.mbfbioscience.com/news/2026/03/clearscope-a-fully-integrated-light-sheet-theta-microscope-for-sub-micron-resolution-imaging#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Fri, 13 Mar 2026 14:03:29 +0000</pubDate>
				<category><![CDATA[Company News]]></category>
		<category><![CDATA[ClearScope®]]></category>
		<category><![CDATA[Light Sheet]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=48790</guid>

					<description><![CDATA[<p>A new peer-reviewed study describes the design and capabilities of ClearScope®, MBF Bioscience&#8217;s fully integrated light-sheet theta microscope for high-resolution 3D...</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2026/03/clearscope-a-fully-integrated-light-sheet-theta-microscope-for-sub-micron-resolution-imaging">Breaking the size barrier: ClearScope light sheet microscope paper published in Journal of Imaging</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>A new peer-reviewed study describes the design and capabilities of<a href="https://www.mbfbioscience.com/products/clearscope" target="_blank" rel="noopener"> ClearScope</a><sup>®</sup>, MBF Bioscience&#8217;s fully integrated light-sheet theta microscope for high-resolution 3D imaging of large biological specimens without lateral size constraints.</p>
<p>&nbsp;</p>
<p><strong>Reference</strong></p>
<p>Fay, M. G., Lang, P. J., Denu, D. S., et al. (2026). ClearScope: A Fully Integrated Light-Sheet Theta Microscope for Sub-Micron-Resolution Imaging Without Lateral Size Constraints. <em>Journal of Imaging</em>. <a href="https://doi.org/10.3390/jimaging12030118">https://doi.org/10.3390/jimaging12030118</a></p>
<p>&nbsp;</p>
<p><strong>Background</strong></p>
<p>Three-dimensional imaging of intact organs and large tissue samples is critical for studying neural connectivity and structural changes in neurological disorders. While light sheet microscopy has become a leading tool for imaging cleared tissues, conventional systems face a fundamental limitation: the orthogonal arrangement of illumination and detection optics constrains the lateral size of specimens that can be imaged — making it impossible to capture intact large rodent brains or human tissue sections in their entirety.</p>
<p>&nbsp;</p>
<p><strong>About ClearScope</strong></p>
<p><a href="https://www.mbfbioscience.com/products/clearscope">ClearScope</a> is based on light sheet theta microscopy (LSTM), a technology developed by Professor Raju Tomer and colleagues at Columbia University. Unlike traditional light sheet systems, LSTM uses two oblique illumination paths paired with perpendicular detection optics — enabling imaging of specimens with effectively unconstrained lateral dimensions while maintaining subcellular resolution.</p>
<p>&nbsp;</p>
<p>Part of our broader light sheet microscopy platform &#8211; built to push the boundaries of 3D imaging</p>
<p>&nbsp;</p>
<p>ClearScope is a technological cousin to <a href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener">SLICE</a>, MBF Bioscience&#8217;s newest light sheet microscope system. Together they reflect our commitment to expanding the boundaries of 3D biological imaging — from connectomics and systems neuroscience to vascular biology, cancer biology, and organoid research.</p>
<p>&nbsp;</p>
<p>We&#8217;re grateful to our collaborators at Columbia University and NYU Langone Health for their partnership in this work.</p>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2026/03/clearscope-a-fully-integrated-light-sheet-theta-microscope-for-sub-micron-resolution-imaging">Breaking the size barrier: ClearScope light sheet microscope paper published in Journal of Imaging</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>MBF Bioscience&#8217;s SLICE Wins Prestigious Microscopy Today Innovation Award</title>
		<link>https://www.mbfbioscience.com/news/2025/08/slice-wins-microscopy-today-innovation-award</link>
					<comments>https://www.mbfbioscience.com/news/2025/08/slice-wins-microscopy-today-innovation-award#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Mon, 18 Aug 2025 14:29:19 +0000</pubDate>
				<category><![CDATA[SLICE]]></category>
		<category><![CDATA[Press Release]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<category><![CDATA[Additional Subject Matter]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=45818</guid>

					<description><![CDATA[<p>FOR IMMEDIATE RELEASE &#160; WILLISTON, VT – August 18, 2025 – MBF Bioscience today proudly announces that its revolutionary light sheet microscope,...</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/08/slice-wins-microscopy-today-innovation-award">MBF Bioscience&#8217;s SLICE Wins Prestigious Microscopy Today Innovation Award</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><strong>FOR IMMEDIATE RELEASE<br />
</strong></p>
<p>&nbsp;</p>
<p><strong>WILLISTON, VT – August 18, 2025</strong> – MBF Bioscience today proudly announces that its revolutionary light sheet microscope, <a href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener">SLICE</a>™, has been awarded a Microscopy Today Innovation Award. This prestigious recognition celebrates SLICE as a game-changing solution that is transforming the light sheet microscopy landscape by delivering superior performance at an exceptionally accessible price point, democratizing advanced 3D imaging and empowering laboratories of all sizes to pursue breakthrough research.</p>
<p>&nbsp;</p>
<p>The Microscopy Today Innovation Award recognizes instruments and accessories that represent significant advancements in the field of microscopy. SLICE was selected for its innovative engineering, which addresses the critical barriers of cost and complexity that have long limited access to high-end light sheet technology.</p>
<p>&nbsp;</p>
<p>&#8220;We are truly honored to receive the Microscopy Today Innovation Award, as it is a powerful validation of our mission to democratize advanced science,&#8221; said Jack Glaser, President of MBF Bioscience. &#8220;SLICE was born from the idea that breakthrough research shouldn&#8217;t be constrained by budget or complexity. This award is a testament to our team&#8217;s commitment to creating a new standard that delivers superior image quality and unmatched value to every lab.&#8221;</p>
<p>&nbsp;</p>
<p>Unlike legacy systems that typically cost hundreds of thousands of dollars, SLICE is a complete turnkey solution available for under $75,000. Its innovative optical design delivers demonstrably higher image quality, with clearer images and increased signal-to-noise than many more expensive systems. The SLICE offering also includes the powerful BrightSLICE software, providing a seamless acquisition-to-analysis workflow without the need for costly external licenses.</p>
<p>&nbsp;</p>
<p>Dr. Raju Tomer, Associate Professor at Columbia University and the inventor of the foundational technology behind SLICE, added, &#8221; We are deeply honored by this recognition from the global microscopy community for our efforts to make high-performance light-sheet microscopy accessible to all. We have seen firsthand how this technology can profoundly transform our understanding of biological systems, yet it has remained largely inaccessible to most researchers and clinicians worldwide. We hope this breakthrough will catalyze new discoveries and empower data-driven innovations in human health. We are very grateful to our collaborators at MBF Bioscience for helping turn this vision into reality.&#8221;</p>
<p>&nbsp;</p>
<p>The SLICE system&#8217;s transparent and all-inclusive annual support model further sets it apart, with a predictable annual fee that covers both hardware maintenance and comprehensive software support. This approach, combined with its streamlined design, makes SLICE an ideal solution for academic labs, microscopy core facilities, and biopharmaceutical R&amp;D teams seeking to accelerate their research pipelines.</p>
<p>&nbsp;</p>
<p><strong>About MBF Bioscience</strong></p>
<p>MBF Bioscience is a pioneering developer of advanced microscopy and imaging solutions, specializing in multi-photon microscopy, light sheet microscopy, unbiased stereology, neuron tracing, fiber photometry, and AI-powered image analysis systems for neuroscience and life sciences researchers. With over 35 years of innovation, MBF Bioscience transforms scientific discovery by creating cutting-edge tools that deliver unparalleled accuracy, reproducibility, and research acceleration to help scientists worldwide to push the boundaries of what&#8217;s possible.</p>
<p>&nbsp;</p>
<p><strong>Media Contact:</strong> Pasang Sherpa, Marketing Manager</p>
<p><strong>Phone</strong>: +1 (802) 288-9290</p>
<p><strong>Email:</strong> <a href="mailto:pasang@mbfbioscience.com">pasang@mbfbioscience.com</a></p>
<p><strong> </strong></p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/08/slice-wins-microscopy-today-innovation-award">MBF Bioscience&#8217;s SLICE Wins Prestigious Microscopy Today Innovation Award</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></content:encoded>
					
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		<title>The SLICE Advantage: Why Our Innovative Approach Outperforms Legacy Light Sheet Microscopes</title>
		<link>https://www.mbfbioscience.com/news/2025/07/slice-outperforms-legacy-light-sheet-microscopes</link>
					<comments>https://www.mbfbioscience.com/news/2025/07/slice-outperforms-legacy-light-sheet-microscopes#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Thu, 24 Jul 2025 13:17:14 +0000</pubDate>
				<category><![CDATA[SLICE]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=45159</guid>

					<description><![CDATA[<p>In our recent discussions, we&#8217;ve introduced SLICE as a revolutionary light sheet microscope, making high-performance 3D imaging accessible for under $99,000....</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/07/slice-outperforms-legacy-light-sheet-microscopes">The SLICE Advantage: Why Our Innovative Approach Outperforms Legacy Light Sheet Microscopes</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>In our recent discussions, we&#8217;ve introduced <a href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener">SLICE as a revolutionary light sheet microscope</a>, making high-performance 3D imaging accessible for under $99,000. We&#8217;ve highlighted its integrated BrightSLICE software and transparent $5,000 annual support. For many, such claims might raise a natural question: <em>how can a system that costs so much less also deliver superior image quality and a better overall experience than those multi-hundred-thousand-dollar legacy machines?</em></p>
<p>&nbsp;</p>
<p>This is the core of the SLICE advantage, and it&#8217;s rooted in a fundamental shift in design philosophy.</p>
<p>&nbsp;</p>
<p><strong>The Legacy Challenge: Complexity, Cost, and Compromise</strong></p>
<p>&nbsp;</p>
<p>Traditional light sheet microscopes, while powerful, often reflect an older engineering paradigm. They typically feature:</p>
<p>&nbsp;</p>
<ul>
<li><strong>Overly Complex Designs:</strong> Built with intricate optical paths and a multitude of proprietary, highly specialized components that are expensive to manufacture and maintain.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Fragmented Ecosystems:</strong> Hardware from one vendor, software from another, third-party analysis tools from a third – leading to workflow inefficiencies, compatibility issues, and compounding costs.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>High Maintenance &amp; Downtime:</strong> Their complexity often translates to higher failure rates, lengthy repair times, and exorbitant annual service contracts.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Steep Learning Curves:</strong> Requiring highly specialized operators and extensive training, creating bottlenecks in busy labs and core facilities.</li>
</ul>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p><strong>The SLICE Solution: Innovation Leading to Superiority</strong></p>
<p>&nbsp;</p>
<p>SLICE is fundamentally different. Our engineering team challenged the assumption that advanced microscopy must be prohibitively expensive and complex. Instead, we focused on innovative optical designs and smart component integration to achieve breakthrough performance through elegance and efficiency, not brute-force complexity.</p>
<p>&nbsp;</p>
<ul>
<li><strong>Superior Image Quality by Design:</strong> We&#8217;ve achieved a pioneering optical path that delivers clearer, higher-resolution images with less aberration and increased signal-to-noise, surpassing what many traditional, more expensive systems can offer. This isn&#8217;t a trade-off for affordability; it&#8217;s a direct result of a modern, optimized design that outperforms older architectures. Your data will be cleaner, your insights sharper, and your publications more impactful.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Robust Simplicity:</strong> By eliminating unnecessary complexity and leveraging cutting-edge engineering principles, SLICE is inherently more robust and reliable. This means significantly less downtime for your research and a dramatically lower annual maintenance cost.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Truly Integrated Workflow:</strong> Our BrightSLICE software is not an afterthought; it&#8217;s an integral part of the SLICE experience. Developed in parallel with the hardware, BrightSLICE provides seamless data acquisition, processing, 3D visualization, and advanced analysis – all included within the transparent annual $5,000 support fee. This unified platform eliminates the need for expensive third-party software licenses and the headaches of managing disparate systems.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Empowering Accessibility:</strong> Because SLICE is designed for straightforward setup and operation, it breaks down the barrier of needing highly specialized personnel. More researchers can gain hands-on experience, accelerating individual projects and maximizing instrument utilization in shared facilities.</li>
</ul>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p><strong>Investing in the Future of Your Research</strong></p>
<p>&nbsp;</p>
<p>Choosing <a href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener">SLICE</a> isn&#8217;t just a budget-conscious decision; it&#8217;s a strategic investment in a microscopy platform that is built for the demands of modern research. It means:</p>
<p>&nbsp;</p>
<ul>
<li><strong>More Budget for Science:</strong> Freeing up funds previously tied to instrument acquisition, maintenance, and software licenses for reagents, personnel, and new research directions.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Faster Discoveries:</strong> Reduced downtime, intuitive workflows, and readily available analysis tools accelerate your path from experiment to insight.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li><strong>Greater Independence:</strong> Bringing powerful capabilities in-house for individual labs, and expanding service offerings for core facilities.</li>
</ul>
<p>&nbsp;</p>
<p>&nbsp;</p>
<p>At MBF Bioscience, we are committed to empowering discovery. With SLICE, we invite you to move beyond the limitations of legacy systems and embrace a new standard in light sheet microscopy that delivers superior image quality, unmatched value, and truly accessible power.</p>
<p>&nbsp;</p>
<p>Ready to experience the SLICE advantage for yourself?</p>
<p>&nbsp;</p>
<p style="text-align: center;">
<span style="color: #3366ff;"><strong><a style="color: #3366ff;" href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener">Learn more about SLICE </a>         <span style="color: #333333;">|</span>     <a style="color: #3366ff;" href="https://www.mbfbioscience.com/request-more-information?wpf12510_6=SLICE&amp;wpf12510_25=I%20would%20like%20more%20information" target="_blank" rel="noopener">Request more information</a></strong></span></p>
<p>&nbsp;</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/07/slice-outperforms-legacy-light-sheet-microscopes">The SLICE Advantage: Why Our Innovative Approach Outperforms Legacy Light Sheet Microscopes</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></content:encoded>
					
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		<title>SLICE: Bringing Affordable Light Sheet Imaging to Your Lab</title>
		<link>https://www.mbfbioscience.com/slice-breakthrough-light-sheet-imaging</link>
					<comments>https://www.mbfbioscience.com/slice-breakthrough-light-sheet-imaging#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Mon, 07 Jul 2025 17:43:44 +0000</pubDate>
				<category><![CDATA[SLICE]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=44793</guid>

					<description><![CDATA[<p>For years, light sheet microscopy has stood out as a powerful technique, enabling stunning 3D imaging of large, live, and delicate...</p>
<p>The post <a href="https://www.mbfbioscience.com/slice-breakthrough-light-sheet-imaging">SLICE: Bringing Affordable Light Sheet Imaging to Your Lab</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>For years, light sheet microscopy has stood out as a powerful technique, enabling stunning 3D imaging of large, live, and delicate biological samples. Its unique ability to provide deep tissue penetration with minimal phototoxicity has driven significant discoveries across neuroscience, developmental biology, and beyond.</p>
<p>&nbsp;</p>
<p>However, the path to acquiring this cutting-edge technology has been steep for most. High-end legacy light sheet systems often come with instrument price tags ranging from $350,000 to over $750,000, frequently escalating further with necessary add-ons like specialized objectives and multiple laser lines. This substantial upfront investment, coupled with complex operation and the necessity for expensive, separate annual service contracts and software licenses (often totaling $65,000 or more per year for a competitor&#8217;s system), has largely confined this transformative technology to a select few well-funded core facilities or specialized research institutions.</p>
<p>&nbsp;</p>
<p>The paradigm is shifting.</p>
<p>&nbsp;</p>
<p><strong>Move Beyond Traditional Light Sheet Microscopes. Meet SLICE.</strong></p>
<p>At MBF Bioscience, our mission is to empower scientific discovery by making advanced tools truly accessible. We developed <strong><a href="https://www.mbfbioscience.com/products/slice" target="_blank" rel="noopener"><span style="color: #226ab3;">SLICE: The New Standard in Light Sheet Microscopy</span></a></strong> to directly address the economic and operational barriers that have historically limited access to this crucial technology.</p>
<p>&nbsp;</p>
<p><strong>How Innovative Design Delivers Superior Image Quality and Unprecedented Affordability</strong></p>
<p>Unlike legacy light sheet systems that often rely on older, less optimized designs and costly, custom-fabricated components, SLICE is engineered from the ground up using groundbreaking optical designs and advanced manufacturing techniques. This innovation allows us to achieve both dramatic cost reductions and deliver image quality that is not just comparable, but demonstrably superior to many legacy systems.</p>
<p>&nbsp;</p>
<ul>
<li>Pioneering Optical Path: SLICE incorporates a more efficient, simplified optical layout that achieves high performance while fundamentally reducing manufacturing complexity. This innovative approach yields clearer, higher-resolution images with less aberration and increased signal-to-noise, surpassing what many traditional, more expensive systems can offer.</li>
</ul>
<p>&nbsp;</p>
<ul>
<li>Next-Generation Engineering: By focusing on smart design and leveraging the latest advancements in microscopy engineering, we&#8217;ve bypassed the exorbitant costs associated with older, less optimized designs. This allows us to deliver top-tier performance and superior image fidelity without the &#8220;boutique&#8221; pricing of historically specialized parts.</li>
</ul>
<p>&nbsp;</p>
<p>This modern approach to microscopy engineering allows us to offer SLICE at a disruptive acquisition cost of less than $99,000. This isn&#8217;t a scaled-down toy; it&#8217;s a meticulously engineered instrument designed for serious science that fits within typical grant budgets and redefines the entry point for advanced 3D imaging.</p>
<p>&nbsp;</p>
<p><strong>Transparent and All-Inclusive Annual Support &amp; Software<br />
</strong></p>
<p>Beyond the initial purchase, the long-term operational costs of traditional systems can be substantial. Legacy systems often require separate, costly annual service contracts (e.g., 10% of instrument cost) and additional annual licenses for image processing, analysis, and visualization software.</p>
<p>&nbsp;</p>
<p>Our annual cost of ownership for SLICE is a transparent $5,000 per year. This single, comprehensive fee covers both hardware service and ongoing BrightSLICE software updates and technical support. This predictable, bundled fee eliminates hidden costs and simplifies budgeting for your research, offering a dramatic contrast to competitor models.</p>
<p>&nbsp;</p>
<p><strong>Designed for Ease of Use</strong></p>
<p>Operating advanced microscopy should not be a bottleneck. SLICE is engineered for intuitive setup and streamlined workflows, significantly reducing the learning curve. This allows researchers to maximize time on experimentation and data acquisition, rather than instrument operation and troubleshooting. For core facilities, it translates to faster user onboarding and increased instrument throughput.</p>
<p>&nbsp;</p>
<p><strong>Empowering Your Next Discovery</strong></p>
<p>The landscape of light sheet microscopy is evolving, and SLICE is leading the charge by making high-impact 3D imaging both accessible and highly cost-effective, while setting a new benchmark for image quality. Whether your aim is to bring cutting-edge capabilities directly into your individual lab, to enhance and expand the services of your core facility, or to accelerate drug discovery workflows in a biotech setting, SLICE represents a new standard.</p>
<p>&nbsp;</p>
<p>Don&#8217;t let historical cost structures and outdated technology limit your scientific potential. Discover how SLICE can power your next breakthrough in high-performance 3D imaging.</p>
<p>&nbsp;</p>
<p>→ <a href="https://www.mbfbioscience.com/request-more-information?wpf12510_6=SLICE&amp;wpf12510_25=I%20would%20like%20more%20information">Request more information</a></p>
<p>&nbsp;</p>
<p>The post <a href="https://www.mbfbioscience.com/slice-breakthrough-light-sheet-imaging">SLICE: Bringing Affordable Light Sheet Imaging to Your Lab</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up</title>
		<link>https://www.mbfbioscience.com/news/2025/06/mbf-bioscience-introduces-slice-light-sheet-microscope</link>
					<comments>https://www.mbfbioscience.com/news/2025/06/mbf-bioscience-introduces-slice-light-sheet-microscope#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Mon, 09 Jun 2025 14:41:24 +0000</pubDate>
				<category><![CDATA[SLICE]]></category>
		<category><![CDATA[Company News]]></category>
		<category><![CDATA[Press Release]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<category><![CDATA[MBF Products & Service Solutions]]></category>
		<category><![CDATA[Light Sheet]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=44624</guid>

					<description><![CDATA[<p>FOR IMMEDIATE RELEASE &#160; MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up &#160; Breakthrough system combines...</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/06/mbf-bioscience-introduces-slice-light-sheet-microscope">MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><strong>FOR IMMEDIATE RELEASE</strong></p>
<p>&nbsp;</p>
<p><strong>MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up</strong></p>
<p>&nbsp;</p>
<p><strong>Breakthrough system combines high performance with unprecedented affordability and compact design, making cutting-edge light sheet microscopy accessible to labs of all sizes</strong></p>
<p>&nbsp;</p>
<p><strong>WILLISTON, VT – June 9, 2025 –</strong> MBF Bioscience, a world leader in quantitative microscopy solutions, today announced the commercial launch of <a href="https://www.mbfbioscience.com/products/slice">SLICE™, a revolutionary light sheet microscope</a> that represents a paradigm shift in advanced imaging technology. Invented by leading researchers at Columbia University, this patent-pending innovation delivers advanced 3D imaging capabilities to research labs of all sizes while offering performance that surpasses systems costing ten times more.</p>
<p>&nbsp;</p>
<p><strong>Breaking Down Barriers to Advanced Imaging</strong></p>
<p>SLICE addresses one of the most significant challenges in modern biological research: the limited accessibility of high-performance light sheet microscopy due to high costs and complex infrastructure requirements. This innovative system offers high sub-micron resolution imaging of biological samples, making it ideal for both individual laboratories and core facilities, effectively democratizing access to what was previously available only to well-funded institutions.</p>
<p>&nbsp;</p>
<p>&#8220;For over three decades, MBF Bioscience has been committed to putting powerful research tools in the hands of scientists everywhere,&#8221; said Jack Glaser, President and Co-founder of MBF Bioscience. &#8220;To advance science, we had to change the math. SLICE represents the embodiment of that mission—delivering the performance researchers need at a price point that makes advanced light sheet microscopy accessible to labs that previously couldn&#8217;t afford this technology. We&#8217;re not just selling a microscope, we&#8217;re opening doors to discoveries that might never have happened otherwise.&#8221;</p>
<p>&nbsp;</p>
<p>Dr. Raju Tomer, Associate Professor of Biological Sciences at Columbia University and inventor of the technology underlying SLICE, added: &#8220;When we developed this approach, our goal was to overcome the fundamental limitations that have kept light sheet microscopy out of reach for so many researchers. SLICE realizes that vision—it&#8217;s a system that doesn&#8217;t compromise on scientific capability while dramatically reducing the barriers to entry. I&#8217;m excited to see how the broader research community will use this technology to push the boundaries of what&#8217;s possible in biological imaging.&#8221;</p>
<p>&nbsp;</p>
<p><strong>Technical Innovation Meets Practical Design</strong></p>
<p>SLICE comes equipped with powerful software for tera-voxel visualization, seamless image stitching, and sophisticated post-processing. The system&#8217;s compact, benchtop-ready design enables placement in diverse research environments, including higher biosafety level facilities, small lab spaces, and even inside incubators where experiments are conducted.</p>
<p>&nbsp;</p>
<p>Key features of SLICE include:</p>
<ul>
<li><strong>Exceptional Performance-to-Cost Ratio</strong>: Performance surpassing systems costing ten times as much</li>
<li><strong>Multi-wavelength Compatibility</strong>: 3 illumination wavelengths for popular labels such as: GFP, Thy1-GFP, eYFP, Alexa 514, 633, 647, mCherry, tdTomato</li>
<li><strong>Versatile Clearing Compatibility</strong>: Compatible with iDISCO, CLARITY, SHANEL, CUBIC, BINAREE and virtually all other optical clearing techniques</li>
<li><strong>Comprehensive Software</strong>: BrightSLICE software for acquisition, visualization, and post-processing</li>
<li><strong>Seamless Integration</strong>: Seamlessly integrates with MBF Bioscience&#8217;s suite of analytical tools, including Neurolucida 360, NeuroInfo and NeuroDeblur</li>
</ul>
<p>&nbsp;</p>
<p><strong>Expanding Research Capabilities</strong></p>
<p>The SLICE system enables researchers to image labeled cells and neuronal processes throughout cleared tissue with exceptional clarity and speed. A wide range of proteins and dyes can be used with SLICE, including c-Fos, tdTomato, mCherry, podocalyxin, CD31, Acta2, mScarlet, and Thy1-eYFP, making it suitable for diverse research applications across neuroscience, developmental biology, cancer research, and beyond.</p>
<p>&nbsp;</p>
<p>Advanced image stitching produces 3D image volumes suitable for MBF Bioscience’s AI-based quantitative analysis software to produce accurate data for analyzing morphometry, cell populations, sub-cellular processes, vasculature and fluorescence properties, enabling researchers to conduct sophisticated analyses previously limited to specialized facilities.</p>
<p>&nbsp;</p>
<p><strong>About MBF Bioscience</strong></p>
<p>MBF Bioscience is a biotech company that develops microscopy software and hardware for bioscience research and education. MBF Bioscience&#8217;s primary location is Williston, Vermont, United States and has offices that market, sell, and support its line of hardware and software products in Ashburn, Virginia; San Diego, California; Europe, and Asia. The company was founded in 1988 as MicroBrightField, Inc. by the father and son team of Dr. Edmund Glaser and Jack Glaser, and has been instrumental in advancing quantitative microscopy for over three decades.</p>
<p>&nbsp;</p>
<p>MBF has received numerous awards for innovation, customer service, and employee satisfaction, including the US Small Business Administration&#8217;s Tibbetts Award for excellence in high technology, the Vermont Small Business Person of the Year award, and the Best Places to Work in Vermont award. MBF&#8217;s tools have been cited in over 16,000 peer-reviewed journal publications, underscoring the company&#8217;s impact on global scientific research.</p>
<p>&nbsp;</p>
<p><strong>Availability and Pricing</strong></p>
<p>SLICE is now available for order, with 30-day lead time for delivery. The complete system, including the light sheet microscope, BrightSLICE software, and computer workstation, is priced under $75,000 – representing exceptional value for advanced 3D imaging capabilities. For demonstrations, technical specifications, or ordering information, visit <a href="https://www.mbfbioscience.com/products/slice">www.mbfbioscience.com/products/slice</a> or contact MBF Bioscience directly.</p>
<p><strong> </strong></p>
<p>&nbsp;</p>
<p><strong>Media Contact:</strong> Pasang Sherpa, Marketing Manager</p>
<p><strong>Phone</strong>: +1 (802) 288-9290</p>
<p><strong>Email:</strong> <a href="mailto:pasang@mbfbioscience.com">pasang@mbfbioscience.com</a></p>
<p>The post <a href="https://www.mbfbioscience.com/news/2025/06/mbf-bioscience-introduces-slice-light-sheet-microscope">MBF Bioscience Introduces SLICE™: We Reimagined Light Sheet Microscopes From the Ground Up</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>Microlucida Software Update: Version 2024.1.3</title>
		<link>https://www.mbfbioscience.com/news/2024/12/microlucida-software-update/</link>
					<comments>https://www.mbfbioscience.com/news/2024/12/microlucida-software-update/#respond</comments>
		
		<dc:creator><![CDATA[mbf_admin]]></dc:creator>
		<pubDate>Thu, 19 Dec 2024 19:02:41 +0000</pubDate>
				<category><![CDATA[Microlucida®]]></category>
		<category><![CDATA[Software & Microscope Integrated Systems]]></category>
		<category><![CDATA[MBF Products & Service Solutions]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=42499</guid>

					<description><![CDATA[<p>We are pleased to announce the release of Microlucida® version 2024.1.3, which introduces key updates to offline software licensing. These updates enhance the functionality and ensure uninterrupted use of the software on systems without internet access.</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2024/12/microlucida-software-update/">Microlucida Software Update: Version 2024.1.3</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><span style="font-size: 14pt;"><strong>Important Update for Microlucida<span style="font-size: 8pt;"><sup>®</sup></span> Offline Licenses</strong></span></p>
<p>&nbsp;</p>
<p>We are pleased to announce the release of Microlucida<sup>®</sup> version 2024.1.3, which introduces key updates to offline software licensing. These updates enhance the functionality and ensure uninterrupted use of the software on systems without internet access.</p>
<p>&nbsp;</p>
<p><strong>Key Updates</strong></p>
<ul>
<li>
<p><strong>Offline Licensing Update:</strong><br />
Reactivation is now required for systems operating without internet connectivity.</p>
</li>
<li>
<p><strong>Activation Process:</strong><br />
To obtain a new offline Activation Key, please fill out this<a href="https://www.mbfbioscience.com/advanced-support"> webform</a>. Detailed instructions for completing the offline authorization process will be provided.</p>
</li>
<li>
<p><strong>Support Documentation:</strong><br />
Step-by-step instructions for offline activation are available in the <a href="https://www.mbfbioscience.com/help/microlucida/Content/File/OfflineSoftwareActivation.htm">Microlucida User Guide </a>for your convenience.</p>
</li>
</ul>
<p>&nbsp;</p>
<p>For additional support or questions, please contact our customer support team at <strong><a rel="noopener">support@mbfbioscience.com</a></strong>.</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2024/12/microlucida-software-update/">Microlucida Software Update: Version 2024.1.3</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>Introducing SLICE™: A new era in low-cost, high-performance light-sheet microscopy</title>
		<link>https://www.mbfbioscience.com/news/2024/10/introducing-slice</link>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Wed, 02 Oct 2024 15:59:13 +0000</pubDate>
				<category><![CDATA[SLICE]]></category>
		<category><![CDATA[Company News]]></category>
		<category><![CDATA[Press Release]]></category>
		<category><![CDATA[Scientific Applications & Use Cases]]></category>
		<category><![CDATA[Light Sheet]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/?p=38237</guid>

					<description><![CDATA[<p>Throughout my career, I&#8217;ve been driven by a singular goal: to advance scientific research by making cutting-edge tools accessible to researchers...</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2024/10/introducing-slice">Introducing SLICE™: A new era in low-cost, high-performance light-sheet microscopy</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>Throughout my career, I&#8217;ve been driven by a singular goal: to advance scientific research by making cutting-edge tools accessible to researchers worldwide. Today, I&#8217;m thrilled to share news that I believe will significantly impact our field.</p>
<p>&nbsp;</p>
<p>In just a few days, at the Society for Neuroscience meeting in Chicago, we will be unveiling <a href="https://www.mbfbioscience.com/products/slice">SLICE</a> – our new affordable light sheet microscope that truly redefines what&#8217;s possible in imaging technology. <a href="https://www.mbfbioscience.com/products/slice">SLICE</a> is the result of our collaboration with leading microscopy researchers at Columbia University, embodying our mission to support &#8220;Big Science in labs of all sizes&#8221;.</p>
<p>&nbsp;</p>
<p>What makes <a href="https://www.mbfbioscience.com/products/slice">SLICE</a> extraordinary and such a transformative technology? Let me share some key points:</p>
<ul>
<li>Performance on par with systems costing ten times as much</li>
<li>Resolution of ~1 μm laterally and ~5 μm axially, resolves cells and neuronal processes throughout the brain</li>
<li>Three-wavelength imaging capability</li>
<li>Compatible with iDISCO, CLARITY, SHANEL, BINAREE and other optical clearing techniques</li>
</ul>
<p>&nbsp;</p>
<p>Most importantly, we&#8217;re offering <a href="https://www.mbfbioscience.com/products/slice">SLICE</a> at an introductory price under $50,000 for a limited time, including lasers and a computer workstation. This is not just a price point; it&#8217;s a statement of our commitment to democratizing access to advanced research tools.</p>
<p>&nbsp;</p>
<p>I personally invite you to visit us at Booth 781 during SfN to learn about our exclusive conference offers designed to make this innovative technology even more accessible. See SLICE in action, and let&#8217;s discuss how it can propel your research forward. If you can&#8217;t make it to SfN, please visit our website <a href="http://www.mbfbioscience.com/products/SLICE" target="_blank" rel="noopener noreferrer" data-link-type="web">SLICE</a> for detailed information.</p>
<p>&nbsp;</p>
<p>In my 30 years in this field, I&#8217;ve seen many advances, but SLICE stands out as a true game-changer. It has the potential to accelerate research across multiple disciplines, and I couldn&#8217;t be more excited to share it with you.</p>
<p>&nbsp;</p>
<p>We pride ourselves in helping scientists make new discoveries, which is why we are determined to do things that allow more researchers to make more discoveries.</p>
<p>&nbsp;</p>
<p>I look forward to your feedback and to seeing the groundbreaking research that SLICE will enable in your labs.</p>
<p>&nbsp;</p>
<p>Sincerely,</p>
<p>Jack Glaser</p>
<p>President, MBF Bioscience</p>
<p>&nbsp;</p>
<p>The post <a href="https://www.mbfbioscience.com/news/2024/10/introducing-slice">Introducing SLICE™: A new era in low-cost, high-performance light-sheet microscopy</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>MBF Bioscience Solves Your Big Data Challenges</title>
		<link>https://www.mbfbioscience.com/mbf-bioscience-solves-big-data-challenges/</link>
					<comments>https://www.mbfbioscience.com/mbf-bioscience-solves-big-data-challenges/#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Wed, 30 Jun 2021 13:13:05 +0000</pubDate>
				<category><![CDATA[Biolucida]]></category>
		<category><![CDATA[Company News]]></category>
		<category><![CDATA[ClearScope®]]></category>
		<category><![CDATA[MBF Products & Service Solutions]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<category><![CDATA[Big Image Data Management Solutions]]></category>
		<category><![CDATA[Additional Subject Matter]]></category>
		<guid isPermaLink="false">https://www.mbfbioscience.com/blog/?p=7602</guid>

					<description><![CDATA[<p>The ability to efficiently acquire large experimental data sets of 2D, 3D and 4D images is advancing rapidly across science. Tools...</p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-solves-big-data-challenges/">MBF Bioscience Solves Your Big Data Challenges</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p>The ability to efficiently acquire large experimental data sets of 2D, 3D and 4D images is advancing rapidly across science. Tools for effectively managing and analyzing this ’big data’ are something that nearly all researchers need. MBF Bioscience has and continues to address this big data need.</p>
<p>&nbsp;</p>
<p>Modern imaging devices can produce data sets sized in the TBs. For example, our cutting edge <a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener">ClearScope light sheet theta microscope</a> allows researchers to image large intact tissue specimens in 3D with subcellular resolution, and generates gigabytes or even terabytes of data per experiment.</p>
<p>&nbsp;</p>
<p>We’ve been working diligently to engineer solutions for the amazingly increased image sizes in image data collection. We have developed and recently released new high-performance technology that addresses the three main pillars of working with big data: managing, viewing, and analyzing big data.</p>
<p>&nbsp;</p>
<p>Specifically, we’ve greatly improved the efficiency of our image handling and processing algorithms. Over the last two years, we’ve massively upgraded our core imaging technologies. Our new imaging engine makes viewing and processing the massive files generated by current imaging tools orders of magnitude more efficient.</p>
<p>&nbsp;</p>
<p>A quote that highlights the amazing progress we’ve made in the big data realm comes from Peter Lang of our Technical Sales team. He says, “Huge data sets that used to take 45-minutes or more to load, now take about five-seconds to open. File size doesn’t really matter anymore”. These improvements also mean that image processing tasks like automated cell detection now take minutes instead of hours. This new imaging technology is included in all of our latest software offerings.</p>
<p>&nbsp;</p>
<p>Our recent image handling and processing improvements fit perfectly with Biolucida, our cloud-based platform for storing, viewing, and accessing big image data. <a href="https://www.mbfbioscience.com/products/biolucida-medical-education">Biolucida</a> lets researchers view and access large data sets from a web browser or any MBF Bioscience analysis software from anywhere with internet access. Big data doesn’t need to be copied around; it can be kept and accessed at one secure location.</p>
<p>&nbsp;</p>
<p>Imaging technologies continue to advance, and data sets will get larger and larger. MBF Bioscience is ready. “Microscopic image data image will soon include Z-stacks comprised of tens-of-thousands of planes for characterizing whole organs at high resolution. Our software engineering team has created a format and architecture that’s ready for efficiently storing, viewing and analyzing these truly huge images.” said MBF Bioscience Product Manager Nate O’Connor. “We’re so excited to be ahead of the curve on not just big data acquisition, but also on being able to manage, view, and analyze it.”</p>
<p>&nbsp;</p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-solves-big-data-challenges/">MBF Bioscience Solves Your Big Data Challenges</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>MBF Bioscience Release ClearScope, Revolutionary Light Sheet Microscope for Imaging Large and Small Cleared Tissue Specimens</title>
		<link>https://www.mbfbioscience.com/mbf-bioscience-set-release-clearscope-advanced-microscopy-system-imaging-large-tissue/</link>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Thu, 10 Dec 2020 19:23:50 +0000</pubDate>
				<category><![CDATA[Company News]]></category>
		<category><![CDATA[ClearScope®]]></category>
		<category><![CDATA[Scientific Applications & Use Cases]]></category>
		<category><![CDATA[Press Release]]></category>
		<category><![CDATA[MBF Products & Service Solutions]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<category><![CDATA[Cleared Tissue and Whole Organ Research]]></category>
		<category><![CDATA[Additional Subject Matter]]></category>
		<category><![CDATA[Light Sheet]]></category>
		<guid isPermaLink="false">http://www.mbfbioscience.com/blog/?p=7505</guid>

					<description><![CDATA[<p>For Immediate Release  Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get...</p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-set-release-clearscope-advanced-microscopy-system-imaging-large-tissue/">MBF Bioscience Release ClearScope, Revolutionary Light Sheet Microscope for Imaging Large and Small Cleared Tissue Specimens</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><span class="TextRun SCXW197336455 BCX9" lang="EN-US" xml:lang="EN-US" data-contrast="auto"><span class="NormalTextRun SCXW197336455 BCX9">For Immediate Release</span></span><span class="EOP SCXW197336455 BCX9" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p><span data-contrast="auto">Williston, VT (December 1</span><span data-contrast="auto">0</span><span data-contrast="auto">, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, </span><a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener"><span data-contrast="none">ClearScope®</span></a><span data-contrast="auto">, has the ability to image whole tissue quickly and gently, in high resolution 3D. </span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p><span data-contrast="auto">The </span><a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener"><span data-contrast="none">ClearScope</span></a><span data-contrast="auto"> system features a unique, two-axis scanning mode that goes beyond the capabilities of typical light sheet microscopy. The patent pending design ensures the specimen is constantly illuminated using the thinnest section of the light sheet optimizing axial resolution. Shadow effects and uneven illumination, which hindered analysis in the past, are eliminated by the new technology, so that even the smallest subcellular structures within the tissue can be visualized with precision. </span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p><span data-contrast="auto">Compatible with a range of tissue clearing techniques, including CLARITY, </span><span data-contrast="auto">iDISCO</span><span data-contrast="auto">, </span><span data-contrast="auto">uDISCO</span><span data-contrast="auto">, </span><span data-contrast="auto">SeeDB</span><span data-contrast="auto"> and </span><span data-contrast="auto">Sca</span><span data-contrast="auto">/e, <a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener">ClearScope</a> has the ability to capture the details of very thick, very large specimens, such as intact tissue from human and primate brains. President and co-founder of MBF Bioscience, Jack Glaser says, “With low photo-bleaching, fast imaging speed, and high image quality, <a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener noreferrer">ClearScope</a> is the most advanced tissue-imaging system in development today, and is set to revolutionize brain research.”</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p><span data-contrast="auto">Designed to work with a wide range of cleared specimens, the system is completely customizable and easily adapted to address the specific needs of researchers across a variety of disciplines. </span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p><span data-contrast="auto">If you are interested in learning more about MBF Bioscience’s advanced new system for imaging large tissue specimens, visit: </span><a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener"><span data-contrast="none">https://www.mbfbioscience.com/clearscope</span></a><span data-contrast="auto"> </span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p style="text-align: center;"><em>###</em></p>
<p><b><span data-contrast="auto">About MBF Bioscience:</span></b><span data-contrast="auto"> MBF Bioscience integrates the world’s leading microscope systems with our revolutionary quantitative imaging and visualization software to accelerate research in the fields of: stereology, neuron and microvasculature reconstruction, vascular analysis, worm tracking, brain mapping and big image data management in medical research and education.</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p><span data-contrast="auto">Since 1988, MBF Bioscience has forged a rich history of creating innovative products to empower biological researchers with the quantitative analysis tools they need to obtain accurate, unbiased results. With offices in North America, Europe, Japan, and South Korea, MBF Bioscience has helped researchers across the globe publish over 15,000 peer-reviewed papers in peer reviewed journals. MBF Bioscience partners with the NIH and distinguished scientists across the world to continue their commitment to </span><span data-contrast="auto">neuroscience research with their software technology, and also in the fields of stem cells, pulmonology, oncology, and toxicology. For more information visit www.mbfbioscience.com or follow MBF Bioscience on Facebook, Twitter, and LinkedIn.</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>&nbsp;</p>
<p style="text-align: center;"><em>###  </em></p>
<p><b><span data-contrast="auto">Media Contact:</span></b><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p><span data-contrast="auto">Pasang Sherpa</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span><br />
<span data-contrast="auto">Marketing Manager</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span><br />
<span data-contrast="auto">1-802-288-9290</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span><br />
<span data-contrast="auto">pasang@mbfbioscience.com</span><span data-ccp-props="{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}"> </span></p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-set-release-clearscope-advanced-microscopy-system-imaging-large-tissue/">MBF Bioscience Release ClearScope, Revolutionary Light Sheet Microscope for Imaging Large and Small Cleared Tissue Specimens</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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		<title>MBF Bioscience Secures Exclusive License from Columbia University to Create New Light-Sheet Microscope System</title>
		<link>https://www.mbfbioscience.com/mbf-bioscience-secures-exclusive-license-columbia-university-create-light-sheet-microscope-system/</link>
					<comments>https://www.mbfbioscience.com/mbf-bioscience-secures-exclusive-license-columbia-university-create-light-sheet-microscope-system/#respond</comments>
		
		<dc:creator><![CDATA[Pasang]]></dc:creator>
		<pubDate>Tue, 04 Feb 2020 14:00:30 +0000</pubDate>
				<category><![CDATA[Company News]]></category>
		<category><![CDATA[ClearScope®]]></category>
		<category><![CDATA[Scientific Applications & Use Cases]]></category>
		<category><![CDATA[Press Release]]></category>
		<category><![CDATA[Microscopy Imaging Systems]]></category>
		<category><![CDATA[MBF Products & Service Solutions]]></category>
		<category><![CDATA[Additional Subject Matter]]></category>
		<category><![CDATA[Cleared Tissue and Whole Organ Research]]></category>
		<category><![CDATA[Light Sheet]]></category>
		<guid isPermaLink="false">http://www.mbfbioscience.com/blog/?p=7300</guid>

					<description><![CDATA[<p>For Immediate Release: Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard...</p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-secures-exclusive-license-columbia-university-create-light-sheet-microscope-system/">MBF Bioscience Secures Exclusive License from Columbia University to Create New Light-Sheet Microscope System</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><strong>For Immediate Release: </strong></p>
<p>Williston, VT (February 04, 2020) — MBF Bioscience’s revolutionary light sheet microscope system, ClearScope, sets a new standard for microscopic imaging.</p>
<p>&nbsp;</p>
<p>The new decade is poised to bring about incredible scientific innovations, and MBF Bioscience is leading the charge in 2020 with the creation of the “light sheet theta microscope” system, <a href="https://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener noreferrer">ClearScope</a>.</p>
<p>&nbsp;</p>
<p>MBF Bioscience secured exclusive license from Columbia University to develop the light sheet theta microscope technology invented by Dr. Raju Tomer. This patent-pending technology in ClearScope leap frogs a number of inherent limitations of other light sheet microscopes. ClearScope will be commercially released this year.</p>
<p>&nbsp;</p>
<p>ClearScope performs high-resolution, 3D imaging of intact, cleared specimens that are larger than any other light sheet microscope is capable of imaging. The technology permits fast imaging speed, high- quality imaging and low photo-bleaching. With the exclusive dual, oblique light sheets providing homogeneous illumination, MBF Bioscience has created a microscope system superior to all existing commercial light sheet microscopes. It is compatible with tissue clearing techniques including CLARITY, uDISCO, SeeDB, Scale and Binaree.</p>
<p>&nbsp;</p>
<p>President and co-founder of MBF Bioscience, Jack Glaser says, “Dr. Tomer’s, revolutionary design of light sheet theta microscopy, and the new capabilities it provides, will have a dramatic impact in scientific research. We are excited to bring this technology to market in ClearScope. ”</p>
<p>&nbsp;</p>
<p>Dr. Raju Tomer, assistant professor of biological sciences at Columbia University says, &#8220;I am very excited about the licensing of our light sheet theta microscope technology to MBF Bioscience for developing a robust and user-friendly ClearScope product. This technology has clear potential to revolutionize high-resolution, quantitative imaging of very large cleared samples. It will also be a valuable instrument for dynamic imaging of live specimens. I think MBF Bioscience, with its extensive expertise in neuroscience imaging and data analytics, is a natural partner to take it beyond a lab instrument stage, to benefit the scientific community at large.&#8221;</p>
<p>&nbsp;</p>
<p>With the ability to image cleared tissue of virtually any XY size, ClearScope has the ability to completely revolutionize the way researchers image and collect data of tissue specimens. ClearScope image data can be analyzed with MBF’s flagship software solutions, <a href="https://www.mbfbioscience.com/neurolucida360" target="_blank" rel="noopener noreferrer">Neurolucida 360</a>, <a href="http://www.mbfbioscience.com/vesselucida360" target="_blank" rel="noopener noreferrer">Vesselucida 360</a> and <a href="https://www.mbfbioscience.com/stereo-investigator" target="_blank" rel="noopener noreferrer">Stereo Investigator</a>.</p>
<p>&nbsp;</p>
<p>To learn more about ClearScope visit: <a href="http://www.mbfbioscience.com/clearscope" target="_blank" rel="noopener noreferrer">www.mbfbioscience.com/clearscope</a></p>
<p>&nbsp;</p>
<p><strong>About MBF Bioscience:</strong> MBF Bioscience integrates the world’s leading microscope systems with our revolutionary quantitative imaging and visualization software to accelerate research in the fields of: stereology, neuron and microvasculature reconstruction, vascular analysis, worm tracking, brain mapping and big image data management in medical research and education.</p>
<p>&nbsp;</p>
<p>Since 1988, MBF Bioscience has forged a rich history of creating innovative products to empower biological researchers with the quantitative analysis tools they need to obtain accurate, unbiased results. With offices in North America, Europe, Japan, and South Korea, MBF Bioscience has helped researchers across the globe publish over 15,000 peer-reviewed papers in peer reviewed journals. MBF Bioscience partners with the NIH and distinguished scientists across the world to continue their commitment to neuroscience research with their software technology, and also in the fields of stem cells, pulmonology, oncology, and toxicology. For more information visit <a href="http://www.mbfbioscience.com">www.mbfbioscience.com</a> or follow MBF Bioscience on <a href="https://www.facebook.com/mbfbioscience">Facebook</a>, <a href="https://twitter.com/MBFBioscience">Twitter</a>, and <a href="https://www.linkedin.com/company/204525/">LinkedIn</a>, or compete in our image contest at <a href="http://www.neuroart.com">www.neuroart.com</a></p>
<p style="text-align: center;">###</p>
<p>&nbsp;</p>
<p><strong>Media Contact:</strong><br />
Pasang Sherpa<br />
Marketing Manager<br />
1-802-288-9290/ pasang@mbfbioscience.com</p>
<p>The post <a href="https://www.mbfbioscience.com/mbf-bioscience-secures-exclusive-license-columbia-university-create-light-sheet-microscope-system/">MBF Bioscience Secures Exclusive License from Columbia University to Create New Light-Sheet Microscope System</a> appeared first on <a href="https://www.mbfbioscience.com">MBF Bioscience</a>.</p>
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