The heart has a “little brain.” It’s a network of neurons known as the intrinsic cardiac nervous system (ICNS), and it plays a key role in regulating cardiac activity. Building on previous research (Achanta et al., 2020), which resulted in a 3D map of the rat ICNS, a new study by a team of scientists from the University of Central Florida, Thomas Jefferson University, the University...
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I suspect many of you are thinking about what “reopening” laboratories and offices post-pandemic might look like. What things could (and should) be done remotely? How will we adjust to our old, and new, social norms? These are questions we’re wrestling with at MBF Bioscience. Here in Vermont, we remain optimistic about beginning to see the light at the end of the tunnel, even while...
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The ability to efficiently acquire large experimental data sets of 2D, 3D and 4D images is advancing rapidly across science. Tools for effectively managing and analyzing this ’big data’ are something that nearly all researchers need. MBF Bioscience has and continues to address this big data need. Modern imaging devices can produce data sets sized in the TBs. For example, our cutting edge ClearScope light sheet...
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MBF Bioscience is now leveraging how neurons learn in order to improve neuroscience research using microscopy. By incorporating artificial neural networks into MBF Bioscience software, we’re equipping neuroscientists with tools that characterize neuronal populations with unprecedented accuracy and anatomic specificity through entire brain volumes. In the webinar titled, “Improved detection of c-fos labeled and pyramidal neurons using deep machine learning in NeuroInfo,” Dr. Gerfen, joined by...
Read More Williston, VT - In 2020, the National Institutes of Health awarded $71.6 million in grants and contracts to Vermont research institutions, supporting job creation and economic vitality in the Green Mountain State. The University of Vermont, the state’s largest employer, led the list of recipients, but right behind UVM is another, lesser known powerhouse in the biomedical research community—MBF Bioscience. An award-winning Vermont business, MBF Bioscience engineers...
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Our state-of-the-art software for performing unbiased stereology is getting an upgrade. Faster, stronger, and better, has been a theme for us lately, as we improve our products across the board, but one place where this is especially striking is in Stereo Investigator. Set for release this spring, the new and improved Stereo Investigator will include a new imaging engine, display engine, automatic camera alignment, automatic lens calibration, the double disector, and live video zooming. “I’m...
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MBF Bioscience is expanding our two photon and laser scanning technology capabilities by acquiring Vidrio Technologies. Vidrio and MBF share a deep passion for helping scientists reveal the fundamental structures and functions of the brain. Our teams are committed to serving the neuroscience community by providing innovative hardware and software tools to help researchers achieve their goals. We are driven to do our part to move...
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We suspect 2020 will always be remembered as the year of big, unexpected questions. Questions like, “How will we do our work together if we’re all working from our homes?" “When will we be able to move around freely again?” “How quickly will the economy bounce back post pandemic?” Questions like these have challenged each and every one of us to remain optimistic, curious, and mindful about what the...
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For Immediate Release Williston, VT (February 11th, 2021)—MicroDynamix™software version 2021 is now available. This state-of-the-art dendritic-spine analysis application enables users to visualize and quantify spine morphology over time using powerful algorithms and detection methods. Developed with input and support from the National Institute of Mental Health (NIMH), the new version of MicroDynamix software makes it easier than ever for neuroscientists to obtain accurate 4D dynamic analyses...
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For Immediate Release Williston, VT (December 10, 2020) — The ability to image large, intact biological specimens is about to get a whole lot better. Developed in collaboration with Columbia University, MBF Bioscience’s revolutionary light sheet theta microscope system, ClearScope®, has the ability to image whole tissue quickly and gently, in high resolution 3D. The ClearScope system features a unique, two-axis scanning mode that goes beyond the capabilities of typical...
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