Research Examples

The following articles elucidate specific studies in which our products were used to either: gather data, perform analysis, or display visual information.

 

Unbiased Stereology in Schizophrenic Brains

Many cortical and subcortical regions in brains from people who had schizophrenia have been anatomically investigated. These regions have been examined for changes in volume, cell number and cell density. Some of the results from these studies have been contradictory and inconclusive.

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Spinal Cord Cells Proliferate After Injury

For Mark Tuszynski and colleagues, Stereo Investgator helps to show oligodendrocytes and astrocytes proliferate after spinal cord injury.

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Identifying the function and type of a cell

Yun Wang and collaborators used Neurolucida to perform 3D quantitative morphological analysis on a cortical cell that may be involved in working memory.

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Neurolucida Helps Define a Possible New Cell Type

Identifying the function of a cell and therefore its type is the holy grail of cellular-level Neuroscience research

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Cell Counting using Unbiased Stereology Techniques

Denise Garcia and colleagues used Stereo Investigator to identify neural progenitors in the adult mouse forebrain.

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3D Anatomical Reconstruction of Labeled Cells in Spinal Cord

Jill Faulkner and colleagues used Neurolucida to reconstruct the effect of reactive astrocyte deletion on spinal cord injury response.

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Dendrite Length and Branch Point Determination

Fred H. Gage and colleagues used Neurolucida to assess neuronal cytoarchitecture, including spine density, branch points, and dendritic lengths.

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Blood Vessel Quantification Using Stereology

Henriette van Pragg and colleagues used Stereo Investigator to quantitate blood vessel number and perimeter in the hippocampi of young and aged mice in an exercise paradigm.

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Counting Fluorescently Labeled Cells Using Stereology

Christoph Schmitz used the Stereo Investigator Confocal SD system to assess hippocampal cytogenesis simultaneously in multiple channels with fluorescent antibodies against BrdU, NeuN and GFAP.

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