MBF Bioscience Launches Stereo Investigator Whole Slide Edition for Quantitative Analysis of Whole Slide Image Data

Williston, VT – June 29, 2018 – MBF Bioscience is pleased to announce the launch of the Whole Slide Edition of Stereo Investigator. This is a new version of our renown Stereo Investigator software, designed especially for conducting stereology on images from slide scanners.

Featuring a streamlined, user-friendly interface, this new product includes a variety of probes for quantifying number, length, volume, and surface area of cells, structures, and regions of biological tissue. The software works with all 2D microscope images, and is an especially attractive solution for researchers who work mostly, or exclusively, with slide scanners.

The main benefits of Stereo Investigator – Whole Slide Edition include:
· Accurate, unbiased quantitative analysis of images from slide scanners
· Designed workflows and user-interface specifically for analyzing whole slide images
· Compatible with all popular slide scanning file formats
· Enhanced user interface that is easy to use for 2D stereology probes
· Integrates with our Biolucida image management system
· Affordable
· Includes MBF technical and scientific support
· Free trial versions are available

“We’re very excited about the opportunity this gives to many of our customers who want to use stereology to perform quantitative analysis of their whole slide image data. Stereo Investigator – Whole Slide Edition provides a powerful, lower-cost version of Stereo Investigator with a user interface designed specifically for 2D image data,” says MBF Bioscience Director of Sales & Marketing Mark Barton.

For over a decade, Stereo Investigator has been considered the gold standard for carrying out stereological studies on biological tissue, and is cited in peer reviewed publications ten times more than any other stereology system. With the release of Stereo Investigator – Whole Slide Edition, MBF Bioscience continues its dedication to further assisting the research of our valued customers.

For more information about Stereo Investigator Whole Slide Edition and to request a quote, visit http://www.mbfbioscience.com/stereo-investigator-whole-slide-edition

Researchers cited MBF Bioscience systems in 23 papers between 6/8/2018 and 6/22/2018

Stereo Investigator:

Caracciolo, L., Marosi, M., Mazzitelli, J., Latifi, S., Sano, Y., Galvan, L., . . . Carmichael, S. T. (2018). CREB controls cortical circuit plasticity and functional recovery after stroke. Nature Communications, 9(1), 2250. doi: 10.1038/s41467-018-04445-9.

Darling, W. G., Ge, J., Stilwell-Morecraft, K. S., Rotella, D. L., Pizzimenti, M. A., & Morecraft, R. J. (2018). Hand Motor Recovery following Extensive Frontoparietal Cortical Injury is accompanied by Upregulated Corticoreticular Projections in the Monkey. The Journal of Neuroscience. doi: https://doi.org/10.1523/JNEUROSCI.0403-18.2018

George, P. M., Oh, B., Dewi, R., Hua, T., Cai, L., Levinson, A., . . . Steinberg, G. K. (2018). Engineered stem cell mimics to enhance stroke recovery. Biomaterials, 178, 63-72. doi: https://doi.org/10.1016/j.biomaterials.2018.06.010.

Giza, J. I., Kim, J., Meyer, H. C., Anastasia, A., Dincheva, I., Zheng, C. I., . . . Lee, F. S. (2018). The BDNF Val66Met Prodomain Disassembles Dendritic Spines Altering Fear Extinction Circuitry and Behavior. Neuron. doi: https://doi.org/10.1016/j.neuron.2018.05.024.

LaPlaca, M. C., Lessing, M. C., Prado, G. R., Zhou, R., Tate, C. C., Geddes-Klein, D., . . . Zhang, L. (2018). Mechanoporation is a potential indicator of tissue strain and subsequent degeneration following experimental traumatic brain injury. Clinical Biomechanics. doi: https://doi.org/10.1016/j.clinbiomech.2018.05.016.  Continue reading “Researchers cited MBF Bioscience systems in 23 papers between 6/8/2018 and 6/22/2018” »

Researchers cited MBF Bioscience systems in 16 papers between 5/25/2018 and 6/1/2018

Stereo Investigator:

Durmuş, B., Aytül, K., & Sıla, C. (2018). Morphology and quantification of sheep pineal glands at pre‐pubertal, pubertal and post‐pubertal periods. Anatomia, Histologia, Embryologia, 0(0). doi:10.1111/ahe.12359.

Ehara, A., Nakadate, K., Sugimoto, H., Yoshimoto, K., & Ueda, S. (2018). Role of neuronal nitric oxide synthase in slowly progressive dopaminergic neurodegeneration in the Zitter rat. Nitric Oxide, 78, 41-50. doi: https://doi.org/10.1016/j.niox.2018.05.007.

Hain, E. G., Sparenberg, M., Rasińska, J., Klein, C., Akyüz, L., & Steiner, B. (2018). Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion. Journal of Neuroinflammation, 15(1), 162. doi: 10.1186/s12974-018-1179-4.

Harrell, C. S., Zainaldin, C., McFarlane, D., Hyer, M. M., Stein, D., Sayeed, I., & Neigh, G. N. (2018). High-fructose diet during adolescent development increases neuroinflammation and depressive-like behavior without exacerbating outcomes after stroke. Brain, Behavior, and Immunity. doi: https://doi.org/10.1016/j.bbi.2018.05.018.

Nagahama, H., Nakazaki, M., Sasaki, M., Kataoka-Sasaki, Y., Namioka, T., Namioka, A., . . . Honmou, O. (2018). Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction. Brain Research, 1695, 37-44. doi: https://doi.org/10.1016/j.brainres.2018.05.033.  Continue reading “Researchers cited MBF Bioscience systems in 16 papers between 5/25/2018 and 6/1/2018” »

Researchers cited MBF Bioscience systems in 8 papers between 5/14/2018 and 5/25/2018

Stereo Investigator:

Bird, C. W., Taylor, D. H., Pinkowski, N. J., Chavez, G. J., & Valenzuela, C. F. (2018). Long-term Reductions in the Population of GABAergic Interneurons in the Mouse Hippocampus following Developmental Ethanol Exposure. Neuroscience, 383, 60-73. doi: https://doi.org/10.1016/j.neuroscience.2018.05.003.

Harun-Or-Rashid, M., Pappenhagen, N., Palmer, P. G., Smith, M. A., Gevorgyan, V., Wilson, G. N., . . . Inman, D. M. (2018). Structural and functional rescue of chronic metabolically stressed optic nerves through respiration. [10.1523/JNEUROSCI.3652-17.2018]. The Journal of Neuroscience. DOI: https://doi.org/10.1523/JNEUROSCI.3652-17.2018

Obara-Michlewska, M., Ding, F., Popek, M., Verkhratsky, A., Nedergaard, M., Zielinska, M., & Albrecht, J. (2018). Interstitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure. Neurochemistry International. doi: https://doi.org/10.1016/j.neuint.2018.05.007. Continue reading “Researchers cited MBF Bioscience systems in 8 papers between 5/14/2018 and 5/25/2018” »

Researchers cited MBF Bioscience systems in 15 papers between 5/4/2018 and 5/14/2018

Stereo Investigator:

Abdel-Rahman, M., Galhom, R. A., Nasr El-Din, W. A., Mohammed Ali, M. H., & Abdel-Hamid, A. E.-D. S. (2018). Therapeutic efficacy of olfactory stem cells in rotenone induced Parkinsonism in adult male albino rats. Biomedicine and Pharmacotherapy, 103, 1178-1186. doi: https://doi.org/10.1016/j.biopha.2018.04.160.

Apland, J. P., Aroniadou-Anderjaska, V., Figueiredo, T. H., De Araujo Furtado, M., & Braga, M. F. M. (2018). Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats. Neurotoxicity research. doi: 10.1007/s12640-018-9907-1.

Bao, L.-H., Zhang, Y.-N., Zhang, J.-N., Gu, L., Yang, H.-M., Huang, Y.-Y., . . . Zhang, H. (2018). Urate inhibits microglia activation to protect neurons in an LPS-induced model of Parkinson’s disease. Journal of neuroinflammation, 15(1), 131. doi: 10.1186/s12974-018-1175-8.

Duffy, M. F., Collier, T. J., Patterson, J. R., Kemp, C. J., Luk, K. C., Tansey, M. G., . . . Sortwell, C. E. (2018). Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. Journal of neuroinflammation, 15(1), 129. doi: 10.1186/s12974-018-1171-z.

Kiyota, T., Machhi, J., Lu, Y., Dyavarshetty, B., Nemati, M., Zhang, G., . . . Gendelman, H. E. (2018). URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer’s disease. Journal of neuroinflammation, 15(1), 137. doi: 10.1186/s12974-018-1172-y.  Continue reading “Researchers cited MBF Bioscience systems in 15 papers between 5/4/2018 and 5/14/2018” »

Researchers cited MBF Bioscience systems in 14 papers between 4/27/2018 and 5/4/2018

Stereo Investigator:

Bhaduri, B., Abhilash, P. L., & Alladi, P. A. (2018). Baseline striatal and nigral interneuronal protein levels in two distinct mice strains differ in accordance with their MPTP susceptibility. Journal of Chemical Neuroanatomy, 91, 46-54. doi: https://doi.org/10.1016/j.jchemneu.2018.04.005.

Dong, Y., Chunli, L., Jiang, W., & Bingren, H. (2018). Nest‐building activity as a reproducible and long‐term stroke deficit test in a mouse model of stroke. Brain and Behavior. doi:10.1002/brb3.993.

F.B. Beyazal Celiker, L. Tumkaya, t. Mercantepe, G. Turan, A. Yilmaz, M. Beyazal, A. Turan, M.F. Inecikli, M. Kosem. (2018). The effect of gadolinium‐based contrast agents on rat testis. Andrologia. doi:10.1111/and.13031.

Guma, E., Rocchetti, J., Devenyi, G. A., Tanti, A., Mathieu, A., Lerch, J. P., . . . Giros, B. (2018). Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor. Neuroimage. doi: https://doi.org/10.1016/j.neuroimage.2018.04.054.

Kim, D., Hwang, H., Choi, S., Kwon, S. H., Lee, S., Park, J. H., . . . Ko, H. S. (2018). D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model. Acta Neuropathologica Communications, 6(1), 32. doi: 10.1186/s40478-018-0538-9. Continue reading “Researchers cited MBF Bioscience systems in 14 papers between 4/27/2018 and 5/4/2018” »

Researchers cited MBF Bioscience systems in 19 papers between 4/20/2018 and 4/27/2018

Stereo Investigator:

Aguilar-Arredondo, A., & Zepeda, A. (2018). Memory retrieval-induced activation of adult-born neurons generated in response to damage to the dentate gyrus. Brain Structure and Function. doi: 10.1007/s00429-018-1664-7.

Andersen, M. A., Christensen, K. V., Badolo, L., Smith, G. P., Jeggo, R., Jensen, P. H., . . . Sotty, F. (2018). Parkinson’s disease-like burst firing activity in subthalamic nucleus induced by AAV-α-synuclein is normalized by LRRK2 modulation. Neurobiology of Disease, 116, 13-27. doi: https://doi.org/10.1016/j.nbd.2018.04.011.

Finch, D. K., Stolberg, V. R., Ferguson, J., Alikaj, H., Kady, M. R., Richmond, B. W., . . . Freeman, C. M. (2018). Lung Dendritic Cells Drive NK Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Rα.  American Journal of Respiratory and Critical Care Medicine. doi: 10.1164/rccm.201712-2513OC.

Guo, Z., Su, Y., & Lou, H. (2018). GFAP-Positive Progenitor Cell Production is Concentrated in Specific Encephalic Regions in Young Adult Mice.  Neuroscience bulletin. doi: 10.1007/s12264-018-0228-4.

Leem, E., Kim, H.-J., Choi, M., Kim, S., Oh, Y.-S., Lee, K. J., . . . Kim, S. R. (2018). Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo. Cell death & disease, 9(5), 449. doi: 10.1038/s41419-018-0491-3. Continue reading “Researchers cited MBF Bioscience systems in 19 papers between 4/20/2018 and 4/27/2018” »

Researchers cited MBF Bioscience systems in 10 papers between 4/13/2018 and 4/20/2018

Stereo Investigator:

Cordaro, M., Siracusa, R., Crupi, R., Impellizzeri, D., Peritore, A. F., D’Amico, R., . . . Cuzzocrea, S. (2018). 2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease. Molecular Neurobiology. doi: 10.1007/s12035-018-1064-2.

Heilbronner, S. R., Meyer, M. A. A., Choi, E. Y., & Haber, S. N. (2018). How do cortico-striatal projections impact on downstream pallidal circuitry?  Brain Structure and Function. doi: 10.1007/s00429-018-1662-9.

Miguel-Hidalgo, J., Moulana, M., Deloach, P., & Rajkowska, G. (2018). F103. Reduced Extent of Myelin Basic Protein Immunoreactivity in Rat Prelimbic and Orbitofrontal Cortices After Chronic Unpredictable Stress and its Correlation With Connexin 43 and Connexin 30. Biological Psychiatry, 83(9), S277-S278. doi: 10.1016/j.biopsych.2018.02.716.

Misheneva, V., McFarland, R., Jouroukhin, Y., Severance, E., Yolken, R., & Pletnikov, M. (2018). F101. Animal Models of Mood Disorders and the Evaluation of Probiotics. Biological Psychiatry, 83(9), S276-S277. doi: 10.1016/j.biopsych.2018.02.714.

Walters, K. A., Edwards, M. C., Tesic, D., Caldwell, A. S., Jimenez, M., Smith, J. T., & Handelsman, D. J. (2018). The Role of Central Androgen Receptor Actions in Regulating the Hypothalamic-Pituitary-Ovarian Axis. Neuroendocrinology. doi: https://doi.org/10.1159/000487762 Continue reading “Researchers cited MBF Bioscience systems in 10 papers between 4/13/2018 and 4/20/2018” »

Researchers cited MBF Bioscience systems in 16 papers between 4/6/2018 and 4/13/2018

Stereo Investigator: 

Chen, C., Li, X., Ge, G., Liu, J., Biju, K. C., Laing, S. D., . . . Li, S. (2018). GDNF-expressing macrophages mitigate loss of dopamine neurons and improve Parkinsonian symptoms in MitoPark mice. Scientific Reports, 8(1), 5460. doi: 10.1038/s41598-018-23795-4.

Demars, F., Clark, K., Wyeth, M. S., Abrams, E., & Buckmaster, P. S. (2018). A single subconvulsant dose of domoic acid at mid-gestation does not cause temporal lobe epilepsy in mice. Neurotoxicology. doi: https://doi.org/10.1016/j.neuro.2018.04.001.

Garrett, L., Ung, M. C., Heermann, T., Niedermeier, K. M., & Hölter, S. (2018). Analysis of Neuropsychiatric Disease‐Related Functional Neuroanatomical Markers in Mice. Current Protocols in Mouse Biology, 8(1), 79-128. doi:10.1002/cpmo.37.

Piontkewitz, Y., Arad, M., & Weiner, I. (2018). T194. BRAIN STRUCTURAL AND BEHAVIORAL ABNORMALITIES FOLLOWING PRENATAL EXPOSURE TO MATERNAL INFLAMMATION ARE PREVENTED BY EARLY BUT NOT LATE INTERVENTION. Schizophrenia Bulletin, 44(suppl_1), S191-S192. doi: 10.1093/schbul/sby016.470.  Continue reading “Researchers cited MBF Bioscience systems in 16 papers between 4/6/2018 and 4/13/2018” »

Researchers cited MBF Bioscience systems in 27 papers between 3/23/2018 and 4/6/2018

Stereo Investigator: 
Crupi, R., Impellizzeri, D., Cordaro, M., Siracusa, R., Casili, G., Evangelista, M., & Cuzzocrea, S. (2018). N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice.  Molecular Neurobiology. doi: 10.1007/s12035-018-0959-2.

Dingle, A. M., Yap, K. K., Gerrand, Y.-W., Taylor, C. J., Keramidaris, E., Lokmic, Z., . . . Mitchell, G. M. (2018). Characterization of isolated liver sinusoidal endothelial cells for liver bioengineering. Angiogenesis. doi: 10.1007/s10456-018-9610-0.

Duthie, M. S., Pena, M. T., Ebenezer, G. J., Gillis, T. P., Sharma, R., Cunningham, K., . . . Reed, S. G. (2018). LepVax, a defined subunit vaccine that provides effective pre-exposure and post-exposure prophylaxis of M. leprae infection. npj Vaccines, 3(1), 12. doi: 10.1038/s41541-018-0050-z.

Dutta, R. R., Taffe, M. A., & Mandyam, C. D. (2018). Chronic administration of amphetamines disturbs development of neural progenitor cells in young adult nonhuman primates. Progress in Neuro-Psychopharmacology and Biological Psychiatry. doi: https://doi.org/10.1016/j.pnpbp.2018.03.023.

Hormigo, S., López, D. E., Cardoso, A., Zapata, G., Sepúlveda, J., & Castellano, O. (2018). Direct and indirect nigrofugal projections to the nucleus reticularis pontis caudalis mediate in the motor execution of the acoustic startle reflex. Brain Structure and Function. doi: 10.1007/s00429-018-1654-9.

Continue reading “Researchers cited MBF Bioscience systems in 27 papers between 3/23/2018 and 4/6/2018” »