Drs. May-Britt and Edvard Moser Image from GEIR MOGEN / NTNU
Drs. May-Britt and Edvard Moser were awarded the 2014 Nobel Prize in Physiology or Medicine for discovering the cells that form a network for spatial navigation in the brain, and we’re proud to say they are MBF Bioscience customers and used Neurolucida in their research.
In 2006, the Norwegian husband and wife team published a paper in the journal Science entitled “Conjunctive Representation of Position, Direction, and Velocity in Entorhinal Cortex” – a pivotal step in a line of research initiated in 1971 by co-laureate Dr. John O’Keefe (The Hippocampus as a Spatial Map). In their study, the scientists used Neurolucida to create 3D reconstructions of a complex network of neurons that make it possible for rats, and other animals, including humans, to navigate the world around them.
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The Nobel Prize in Physiology or Medicine was awarded to Drs. Thomas Südhof, James Rothman, and Randy Schekman for discovering the principles of how molecules are transported within cells and in between cells and how they are delivered to the right place at the right time. Disruptions in this precise system are implicated in numerous neurological and immunological disorders.
Dr. Sudhof uncovered how neurotransmitters are released into a synaptic cleft precisely when they need to be. His research explained the molecular machinery that responds to an influx of calcium and signals the release of neurotransmitters.
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