Researchers Control Rodent Depression With Optogenetics

Imagine if you could switch your depression off like a light. Researchers did it in mice. They used optogenetics to gain more insight into how brain circuits work in cases of depression, and discovered that different types of stress trigger different activity patterns in the same brain circuit.

Two papers published recently in the journal Nature describe how neuronal activity in specific brain circuits in mice can be turned on and off to control depression-like behavior. Both studies used optogenetics, a research method pioneered by one of our customers, Dr. Karl Deisseroth that combines fiber optics and genetic engineering to control the activity of specific neurons. Dr. Deisseroth, a neuroscientist and psychiatrist at Stanford University contributed to both papers. Continue reading “Researchers Control Rodent Depression With Optogenetics” »