Stereo Investigator Contributes to Study Showing Low Zinc Levels Associated With More Cell Deaths in Spinal Cord Injury

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Spinal cord injuries can result in a range of physical disabilities from slight loss of motor function to major paralysis, but little is known about the mechanisms underlying the damage. Scientists affiliated with the Miami Project to Cure Paralysis at the University of Miami are gaining knowledge about how the nervous system responds to spinal cord injuries. Their latest study, published last month in the Journal of Neuroscience Research, suggests that post trauma cell death is associated with low zinc levels.

“The expression of functional NF-kB signaling resulted in a reduction in extracellular zinc levels, thereby inducing glutamate-induced cell death,” the authors say in their paper “Reduced Extracellular Zinc Levels Facilitate Glutamate-Mediated Oligodendrocyte Death After Trauma.

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