Revving engines, blasting sirens, the drummer next door. Despite the myriad sensory stimuli going on around us at any given moment, humans have the ability to stay focused on the task at hand. This skill is due to a part of the brain known as the neocortex, a six-layer structure whose intricate wiring is largely a mystery. But researchers at the University of Virginia just took a big step toward a broader understanding of how this region works. They discovered two never-before-identified circuits in the rat sensorimotor cortex that help explain how the brain filters information.