We’re about to launch a new tool that will help scientists studying the brain perform their research faster. The new software, called AutoSynapse automatically detects and analyzes pre-synaptic markers such as synaptophysin and post-synaptic markers such as PSD95, then uses nearby dendrites traced with AutoNeuron or Neurolucida to analyze which of those synaptic markers are associated with particular dendrites.
Up until now, this method for analyzing synapses could only be done manually with Neurolucida, but AutoSynapse provides a new type of automated analysis that is not available with any other software.
“AutoSynapse solves a unique and important analysis need of many neuroscientists,” says MBF Bioscience President Jack Glaser. “it automatically detects and quantifies the number of putative synapses on specific dendrites. We developed this tool in conjunction with several of our users. We are especially grateful to Dr. Francisco Alvarez and Travis Rotterman at Emory University.”
This work was supported by a SBIR grant awarded from the NIMH. NIH Grant MH072063.
Visit our booth at Neuroscience 2012, October 13 – 17, in New Orleans to see AutoSynapse in action. And visit our research poster presentation 710.13/FFF27, Automated detection and analysis of putative synapses, Tuesday, Oct 16, 2012, 1:00 PM – 2:00 PM.