Take a Look at the Latest Research Using MBF Systems (week of 1/21/13)

bookshelves-at-the-library_w482_h725

 

Our systems were mentioned in 11 published research papers last week alone.  Take a closer look at some of the research…

 

 

Stereo Investigator:

Neurolucida:

  • Bories, C., Husson, Z., Guitton, M. J., & De Koninck, Y. (2013). Differential Balance of Prefrontal Synaptic Activity in Successful versus Unsuccessful Cognitive Aging. The Journal of Neuroscience33(4), 1344-1356. doi: 10.1523/​JNEUROSCI.3258-12.2013
  • Kim, J. Y., Ash, R. T., Ceballos‐Diaz, C., Levites, Y., Golde, T. E., Smirnakis, S. M., & Jankowsky, J. L. (2013). Viral transduction of the neonatal brain delivers controllable genetic mosaicism for visualising and manipulating neuronal circuits in vivo. European Journal of Neuroscience. doi: 10.1111/ejn.12126
  • Morel, A., Gallay, M. N., Baechler, A., Wyss, M., & Gallay, D. S. (2013). The human insula: architectonic organization and postmortem mri registration. Neuroscience. doi:10.1016/j.neuroscience.2012.12.076
  • Poller, W. C., Madai, V. I., Bernard, R., Laube, G., & Veh, R. W. (2013). A glutamatergic projection from the lateral hypothalamus targets VTA-projecting neurons in the lateral habenula of the rat. Brain Research. doi: 10.1016/j.brainres.2013.01.029
  • Song, C. H., Bernhard, D., Bolarinwa, C., Hess, E. J., Smith, Y., & Jinnah, H. A. (2013). Subtle microstructural changes of the striatum in a DYT1 knock-in mouse model of dystonia. Neurobiology of Disease. doi: 10.1016/j.nbd.2013.01.008

 

Take a Look at the Latest Research Using MBF Systems (week of 1/14/13)

bookshelves-at-the-library_w482_h725

 

Our systems were mentioned in 12 published research papers last week alone.  Take a closer look at some of the research…

 

 

Neurolucida:

Stereo Investigator:

  • Bäck, S., Peränen, J., Galli, E., Pulkkila, P., Lonka-Nevalaita, L., Tamminen, T., Voutilainen, M. H., Raasmaja, A., Saarma, M., Männistö, P. T. and Tuominen, R. K. (2013). Gene therapy with AAV2-CDNF provides functional benefits in a rat model of Parkinson’s disease. Brain and Behavior. doi: 10.1002/brb3.117
  • Cimino, P. J., Yang, Y., Li, X., Hemingway, J. F., Cherne, M. K., Khademi, S. B., … & Keene, C. D. (2013). Ablation of the microglial protein DOCK2 reduces amyloid burden in a mouse model of Alzheimer’s disease. Experimental and Molecular Pathology. doi: 10.1016/j.yexmp.2013.01.002
  • Johansson, J., Mannerås-Holm, L., Shao, R., Olsson, A., Lönn, M., Billig, H., & Stener-Victorin, E. (2013). Electrical vs Manual Acupuncture Stimulation in a Rat Model of Polycystic Ovary Syndrome: Different Effects on Muscle and Fat Tissue Insulin Signaling. PLOS ONE8(1), e54357. doi:10.1371/journal.pone.0054357
  • Kalm, M., Karlsson, N., Nilsson, M. K., & Blomgren, K. (2013). Marie Kalm, Niklas Karlsson, Marie KL Nilsson, Klas Blomgren. Experimental Neurology. doi: 10.1016/j.expneurol.2013.01.006
  • Luk, K. C., Rymar, V. V., Munckhof, P., Nicolau, S., Steriade, C., Bifsha, P., … & Sadikot, A. F. (2013). The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress. Journal of Neurochemistry. doi: 10.1111/jnc.12160
  • Pranski, E. L., Dalal, N. V., Sanford, C. V., Herskowitz, J. H., Gearing, M., Lazo, C., … & Betarbet, R. S. (2013). RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-κB signaling in dopaminergic cells. Neurobiology of Disease. doi: 10.1016/j.nbd.2012.12.018
  • Su, H., Wang, L., Huang, W., Qin, D., Cai, J., Yao, X., … & Pei, D. (2013). Immediate expression of Cdh2 is essential for efficient neural differentiation of mouse induced pluripotent stem cells. Stem Cell Research. doi: 10.1016/j.scr.2013.01.003

Take a Look at the Latest Research Using MBF Systems (week of 1/7/13)

bookshelves-at-the-library_w482_h725

 

Our systems were mentioned in 8 published research papers last week.  Take a closer look at some of the research…

 

Neurolucida:

  • Browning, K. N., Babic, T., Holmes, G. M., Swartz, E. M., & Travagli, R. A. (2013). A critical re-evaluation of the specificity of action of perivagal capsaicin. The Journal of Physiology. doi:10.1113/jphysiol.2012.246827
  • Carlo, C. N., & Stevens, C. F. (2013). Structural uniformity of neocortex, revisited. Proceedings of the National Academy of Sciences. doi:10.1073/pnas.1221398110
  • Carrasco, A., Brown, T. A., Kok, M. A., Chabot, N., Kral, A., & Lomber, S. G. (2013). Influence of Core Auditory Cortical Areas on Acoustically Evoked Activity in Contralateral Primary Auditory Cortex. The Journal of Neuroscience,33(2), 776-789. doi:10.1523/​JNEUROSCI.1784-12.2013
  • Levine, N. D., Rademacher, D. J., Collier, T. J., O’Malley, J. A., Kells, A. P., San Sebastian, W., … & Steece-Collier, K. (2013). Advances in thin tissue Golgi-Cox impregnation: Fast, reliable methods for multi-assay analyses in rodent and non-human primate brain. Journal of Neuroscience Methods. doi: 10.1016/j.jneumeth.2012.12.001
  • Reid, G. A., Chilukuri, N., & Darvesh, S. (2013). Butyrylcholinesterase and the Cholinergic System. Neuroscience. doi: 10.1016/j.neuroscience.2012.12.054

Stereo Investigator:

  • Alexander, M. L., Hill, C. A., Rosenkrantz, T. S., & Fitch, R. H. (2013). Evaluation of the Therapeutic Benefit of Delayed Administration of Erythropoietin following Early Hypoxic-Ischemic Injury in Rodents. Developmental Neuroscience. doi: 10.1159/000345645
  • David, B. T., Ratnayake, A., Amarante, M. A., Reddy, N. P., Dong, W., Sampath, S., … & Elkabes, S. (2013). A toll-like receptor 9 antagonist reduces pain hypersensitivity and the inflammatory response in spinal cord injury. Neurobiology of Disease. doi: 10.1016/j.nbd.2012.12.012
  • Piao, C. S., Stoica, B. A., Wu, J., Sabirzhanov, B., Zhao, Z., Cabatbat, R., … & Faden, A. I. (2013). Late exercise reduces neuroinflammation and cognitive dysfunction after traumatic brain injury. Neurobiology of Disease. doi: 10.1016/j.nbd.2012.12.017

Take a Look at the Latest Research Using MBF Systems (12/24-1/4)

bookshelves-at-the-library_w482_h725

Our systems were mentioned in 13 published research papers over the past couple of weeks.  Take a closer look at some of the research…

Stereo Investigator:

  • Acosta, S. A., Tajiri, N., Shinozuka, K., Ishikawa, H., Grimmig, B., Diamond, D., … & Borlongan, C. V. (2013). Long-Term Upregulation of Inflammation and Suppression of Cell Proliferation in the Brain of Adult Rats Exposed to Traumatic Brain Injury Using the Controlled Cortical Impact Model. PLOS ONE,8(1), e53376. doi:10.1371/journal.pone.0053376
  • Chtarto, A., Bockstael, O., Gebara, E., Vermoesen, K., Melas, C., Pythoud, C., … & Tenenbaum, L. (2013). An Adeno-Associated Virus-Based Intracellular Sensor of Pathological Nuclear Factor-κB Activation for Disease-Inducible Gene Transfer. PLOS ONE8(1), e53156. doi:10.1371/journal.pone.0053156
  • Hua, K., Schindler, M. K., McQuail, J. A., Forbes, M. E., & Riddle, D. R. (2012). Regionally Distinct Responses of Microglia and Glial Progenitor Cells to Whole Brain Irradiation in Adult and Aging Rats. PLOS ONE7(12), e52728. doi:10.1371/journal.pone.0052728
  • Khan, M. M., Dhandapani, K. M., Zhang, Q. G., & Brann, D. W. (2012). Estrogen regulation of spine density and excitatory synapses in rat prefrontal and somatosensory cerebral cortex [Abstract]. Steroids. doi: 10.1016/j.steroids.2012.12.005
  • Kumar, A., Stoica, B. A., Sabirzhanov, B., Burns, M. P., Faden, A. I., & Loane, D. J. (2012). Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states [Abstract]. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2012.11.013
  • Lee, N. C., Shieh, Y. D., Chien, Y. H., Tzen, K. Y., Yu, I., Chen, P. W., … & Hwu, W. L. (2012). Regulation of the dopaminergic system in a murine model of aromatic L-amino acid decarboxylase deficiency [Abstract]. Neurobiology of Disease. doi:10.1016/j.nbd.2012.12.005
  • Littrell, O. M., Granholm, A. C., Gerhardt, G. A., & Boger, H. A. (2013). Glial cell-line derived neurotrophic factor (GDNF) replacement attenuates motor impairments and nigrostriatal dopamine deficits in 12-month-old mice with a partial deletion of GDNFPharmacology Biochemistry and Behavior. doi:10.1016/j.pbb.2012.12.022
  • Uzkeser, M., Sahin, H., Ozogul, B., Cayir, Y., Alper, F., & Emet, M. (2013). Defining the percentage of intra-abdominal hemorrhage in abdominal computerized tomography using stereology in patients with blunt liver injury and determining its relationship with outcomes [Abstract]. The Journal of Trauma and Acute Care Surgery74(1), 224-229. doi: 10.1097/TA.0b013e318270df0e

Neurolucida:

  • Fan, C., Zheng, Y., Cheng, X., Qi, X., Bu, P., Luo, X., … & Cao, Q. (2013). Transplantation of D15A-Expressing Glial-Restricted-Precursor-Derived Astrocytes Improves Anatomical and Locomotor Recovery after Spinal Cord Injury. International Journal of Biological Sciences9(1), 78. doi:10.7150/ijbs.5626
  • Kawabe, T., Kawabe, K., & Sapru, H. N. (2012). Effect of Barodenervation on Cardiovascular Responses Elicited from the Hypothalamic Arcuate Nucleus of the Rat. PLOS ONE7(12), e53111. doi:10.1371/journal.pone.0045180
  • Lopes, A., Torres, D. B., Rodrigues, A. J., Cerqueira, J. J., Pêgo, J. M., Sousa, N., … & Boer, P. A. (2012). Gestational protein restriction induces ca3 dendritic atrophy in dorsal hippocampal neurons but does not alter learning and memory performance in adult offspring. International Journal of Developmental Neuroscience. doi: 10.1016/j.ijdevneu.2012.12.003
  • Maseko, B. C., Jacobs, B., Spocter, M. A., Sherwood, C. C., Hof, P. R., & Manger, P. R. (2012). Qualitative and Quantitative Aspects of the Microanatomy of the African Elephant Cerebellar Cortex [Abstract]. Brain, Behavior and Evolution. doi: 10.1159/000345565
  • Miao, S., Chen, R., Ye, J., Tan, G. H., Li, S., Zhang, J., … & Xiong, Z. Q. (2013). The Angelman Syndrome Protein Ube3a Is Required for Polarized Dendrite Morphogenesis in Pyramidal Neurons. The Journal of Neuroscience,33(1), 327-333. doi:10.1523/jneurosci.2509-12.2013

Take a look at the latest research using MBF systems (Week of 12/10)

bookshelves-at-the-library_w482_h725Our systems were mentioned in 10 published research papers last week.  Take a closer look at some of the research…

Neurolucida:

Stereo Investigator:

Lucivid:

Microlucida:

Science News: Our Weekly Picks From Around the Web

Neuroscientists Propose a Revolutionary DNA-Based Approach to Map Wiring of the Whole Brain
The team, led by Professor Anthony Zador, Ph.D., of Cold Spring Harbor Laboratory, aims to provide a comprehensive account of neural connectivity.
www.cshl.edu (10/22/2012)

Study Identifies Natural Process Activating Brain’s Immune Cells that Could Point Way to Repairing Damaged Brain
The brain’s key “breeder” cells, it turns out, do more than that. They secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health.
med.stanford.edu (10/21/2012)

Max Planck Scientists Aim to Analyse a Whole Mouse Brain Under the Electron Microscope
Scientists at the Max Planck Institute for Medical Research in Heidelberg, Germany have taken a crucial step towards obtaining a complete circuit diagram of the brain of the mouse.
www.mpg.de (10/22/2012)

Brainwave Training Boosts Network for Cognitive Control
A study conducted in Canada has found that training of the well-known brainwave in humans, the alpha rhythm, enhances a brain network responsible for cognitive control.
www.schulich.uwo.ca (10/24/2012)

New Company Hopes to Make Neuroscience a Little Less Intimidating and a Lot More Accessible
Gage hopes to show students that neuroscience can be fun and, in the process, inspire the next generation of neuroscientists.
www.edition.cnn.com (10/19/2012)

Science News: Our Weekly Picks From Around the Web

Disrupted sleep may predict Alzheimer’s 
A disturbed night’s sleep might signal a future diagnosis of Alzheimer’s disease, according to findings presented this week at the annual meeting of the Society for Neuroscience in New Orleans, Louisiana.
www.nature.com (10/18/2012)

 

 

Neuroscientists Find the Molecular ‘When’ and ‘Where’ of Memory Formation
Neuroscientists from New York University and the University of California, Irvine have isolated the “when” and “where” of molecular activity that occurs in the formation of short-, intermediate-, and long-term memories.
www.sciencedaily.com (10/15/2012). View abstract here.

Calcium Reveals Connections Between Neurons
New way to image brain-cell activity could shed light on autism and other psychiatric disorders.
web.mit.edu (10/17/2012). View abstract here.

Brain’s Language Center Has Multiple Roles
Neuroscientists find Broca’s area is really two subunits, each with its own function.
web.mit.edu (10/16/2012)

What Singing Fish Reveal about Speech and Hearing
An unusual singing fish has been teaching biologists and neuroscientists a lot about speech and hearing. Several studies involving the plainfin midshipman fish (Porichthys notatus) were presented at Neuroscience 2012.
blogs.scientificamerican.com (10/16/2012)

Light-Activated Neurons and Ketamine Can Help Treat Depression
A “light switch” for turning on and off depression and the use of ketamine as a nerve connection recovery drug were the research highlights at Neuroscience 2012.
www.wired.co.uk (10/15/2012)

 

Science News: Our Weekly Picks From Around the Web

Scientists Discover Sleeping Brain Behaves as if it’s Remembering Something
UCLA researchers have for the first time measured the activity of a brain region known to be involved in learning, memory and Alzheimer’s disease during sleep.
newsroom.ucla.edu (10/07/2012)

Stem Cells Safe for Rare Brain Disorder
Four young boys with a rare, fatal brain condition have made it through a dangerous ordeal. Scientists have safely transplanted human neural stem cells into their brains.
news.sciencemag.org (10/10/2012)

Brain Changes When You Change Your Mind
Researchers found that the rejection of an old belief correlates with abrupt changes in activity in the medial prefrontal cortex, a brain region involved in cognitive functions such as reward anticipation and decision-making.
www.hhmi.org (10/05/2012)

Brain Scans Can Predict Children’s Reading Ability, Stanford Researchers Say
New research can identify the neural structures associated with poor reading skills in young children, and could lead to an early warning system for struggling students.
news.stanford.edu (10/10/2012)

It’s Music to Their Brains
The Los Angeles Philharmonic Association (LA Phil), the USC Brain and Creativity Institute (BCI) and Heart of Los Angeles (HOLA) announced a research collaboration to investigate the emotional, social and cognitive effects of musical training on childhood brain development.
news.usc.edu (10/09/2012)

The Royal Swedish Academy of Sciences Awards Nobel Prize in Chemistry
Robert Lefkowitz and Brian Kobilka are awarded the 2012 Nobel Prize in Chemistry for groundbreaking discoveries that reveal the inner workings of an important family of G-protein–coupled receptors.
www.nobelprize.org (10/10/2012)

Science News: Our Weekly Picks From Around the Web

Munich Scientists Reprogram Brain Cells Called Pericytes into Neurons
Brain cells called pericytes can be reprogrammed into neurons with just two proteins, pointing to a novel way to treat neurodegenerative disorders.
www.the-scientist.com (10/04/2012)

Neuroscientists Unravel Vegetative State Mystery
By exploring parts of the brain that trigger during periods of daydreaming, neuroscientists from Western University have made a significant breakthrough in understanding what happens in the brain to cause vegetative state.
communications.uwo.ca (10/14/2012)

Ketamine Can Help Improve Brain Function in Rett Syndrome Mice
A study in the Journal of Neurosciences showed that in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating the animals with an FDA-approved anesthesia drug, ketamine.
www.news-medical.net (10/04/2012)
Abstract: www.jneurosci.org

New public brain-scan database opens autism research frontiers
Scientists have a valuable new tool for studying autism: a public database of more than 1,000 brain scans.
scopeblog.stanford.edu (09/28/2012)

Leftover DNA From Sons May Alter Their Mothers’ Brains, Study Says
The Fred Hutchinson Cancer Research Center study also found that women with more male DNA in their brains were less likely to have suffered from Alzheimer’s disease.
www.seattletimes.com (09/27/2012)

McGovern Neuroscientist Constantine-Paton Wins Lifetime Achievement Award
Over the past 30 years, Constantine-Paton has established a reputation as a leading figure in the field of developmental neuroscience. She will be recognized for her achievements during SfN’s annual meeting this month.
web.mit.edu (09/28/2012)