Visit us at the Society for Neuroscience meeting in Washington, DC

Posted on September 28, 2017 by MBF Mindset

The SfN 2017 meeting is the culmination of an exciting year of new technological achievements at MBF Bioscience. Our new version 2017 of Neurolucida, Stereo Investigator, and Neurolucida 360 features a totally re-designed interface and has been an overwhelming success with our customers. We’ve also expanded the stereology family with Stereo Investigator Cleared Tissue edition and Stereo Investigator Whole Slide Imaging edition. And we have received wide enthusiasm for our new optogenetics stand for WormLab, our worm tracking software.

Come see our innovative new system that includes a high-speed, 4-channel laser confocal scanner for fast confocal whole slide imaging in both 2D and 3D. It is creating a new paradigm for big data image acquisition and analysis. You simply will not believe the slide scanning speed we will be demonstrating for confocal imaging.

Curious about new technologies for microvasculature analysis? Come and discover Vesselucida.

Tired of using a printed brain atlas and wish there was an easier way to identify the brain anatomy on your sections? Imagine technology that can automatically identify the anatomical region on your sections by just clicking on it! Come see our new automatic brain mapping technology that matches serial sections of mouse brain to the Allen Brain Atlas.

Visit us at booth #1637 to see the latest advancements in quantitative neuroscience research and learn how our “End-To-End” solutions for Image Acquisition – Image Management – Image Analyses will revolutionize the way you make your next discovery.

If you’ve visited our booth at SfN before, you know how busy we can be. If you’d like to schedule an appointment to reserve the time to meet with us that works best for you, just use this online form. Or just stop by to see us for a personalized demonstration of any of our software or imaging systems.

We are looking forward to seeing you there!

Take a Look at the Latest Research Using MBF Systems (week of 5/20/13)

Posted on May 30, 2013 by MBF Mindset

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Our systems were mentioned in 22 published research papers last week alone. Take a closer look at some of the research…

Neurolucida:

Albrecht, P. J., Hou, Q., Argoff, C. E., Storey, J. R., Wymer, J. P., & Rice, F. L. (2013). Excessive Peptidergic Sensory Innervation of Cutaneous Arteriole–Venule Shunts (AVS) in the Palmar Glabrous Skin of Fibromyalgia Patients: Implications for Widespread Deep Tissue Pain and Fatigue. Pain Medicine. doi: 10.1111/pme.12139
Bessa, S., Quelhas, P., & Amaral, I. F. (2013). Automatic Quantification of Cell Outgrowth from Neurospheres. In Pattern Recognition and Image Analysis (pp. 141-148). Springer Berlin Heidelberg. doi: 10.1007/978-3-642-38628-2_16
Coddington, L. T., Rudolph, S., Vande Lune, P., Overstreet-Wadiche, L., & Wadiche, J. I. (2013). Spillover-Mediated Feedforward Inhibition Functionally Segregates Interneuron Activity. Neuron. doi: 10.1016/j.neuron.2013.04.019
deCampo, D. M., & Fudge, J. L. (2013). Amygdala projections to the lateral bed nucleus of the stria terminalis in the macaque: Comparison with ventral striatal afferents. Journal of Comparative Neurology. doi: 10.1002/cne.23340 Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 5/20/13)” »

Take a Look at the Latest Research Using MBF Systems (week of 5/13/13)

Posted on May 23, 2013 by MBF Mindset

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Our systems were mentioned in 17 published research papers last week alone. Take a closer look at some of the research…

Neurolucida:

Abbasi, S., & Kumart, S. S. (2013). Electrophysiological and morphological characterization of cells in superficial layers of rat presubiculum. Journal of Comparative Neurology. doi: 10.1002/cne.23365
DeBoer, E. M., & Rasin, M. R. (2013). Nucleoside Analog Labeling of Neural Stem Cells and Their Progeny. In Neural Development (pp. 21-37). Humana Press. doi: 10.1007/978-1-62703-444-9_3
Dong, Y. F., Wang, L. X., Huang, X., Cao, W. J., Lu, M., Ding, J. H., … & Hu, G. (2013). Kir6. 1 Knockdown Aggravates Cerebral Ischemia/Reperfusion‐Induced Neural Injury in Mice. CNS neuroscience & therapeutics.
Li, Y., Stam, F. J., Aimone, J. B., Goulding, M., Callaway, E. M., & Gage, F. H. (2013). Molecular layer perforant path-associated cells contribute to feed-forward inhibition in the adult dentate gyrus. Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1306912110 Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 5/13/13)” »

MBF Bioscience Wins Prestigious Tibbetts Award in Recognition of Outstanding Technological Innovation

Posted on May 20, 2013 by MBF Mindset

MBF Bioscience received a prestigious Tibbetts Award during a ceremony at the White House on May 16. The Tibbetts Award recognizes MBF Bioscience for a number of accomplishments including: technological innovation, serving federal Research and Development needs, encouraging diverse participation, and increasing the practical commercial use of federal research.

The Tibbetts Award is given to companies who participate in the Small Business Innovation Research program which is run by the U.S. Small Business Administration. The SBIR program is a highly competitive program that encourages small businesses to engage in Federal Research/Research and Development (R/R&D) that has the potential for commercialization.

From left to right: Roland Tibbetts (sitting), SBIR officer, Jack Glaser, SBIR officer

Jack Glaser receives the Tibbetts Award on behalf of MBF Bioscience. From left to right: Roland Tibbetts (sitting), Karen Mills, SBA Administrator, Jack Glaser, Pravina Raghavan, Director, Innovation and Technology at SBA

From left to right: Meg Grabb (NIMH SBIR Program Officer), Sophie Glaser, Roland Tibbetts, Jack Glaser, Cait Glaser

From left to right: Margaret Grabb, Ph.D, NIMH SBIR/STTR Coordinator, Sophie Glaser, Roland Tibbetts, Jack Glaser, Cait Glaser

Roland Tibbetts, who was instrumental in developing the SBIR program, presented the award to Jack Glaser, President of MBF Bioscience. MBF Bioscience has been an active participant in the SBIR program for many years. It has received numerous SBIR awards that have helped develop many products that bioscience researchers rely on, including Neurolucida, Stereo Investigator, Biolucida, AutoSpine, AutoSynapse, and Virtual Tissue 3D.

MBF was featured in local Vermont media outlets to talk about winning the Tibbetts Award. Jack Glaser was interviewed on a local VT television news station. You can view the segment on the WCAX website. MBF was also highlighted in the Burlington Free Press.

Take a Look at the Latest Research Using MBF Systems (week of 5/6/13)

Posted on May 16, 2013 by MBF Mindset

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Our systems were mentioned in 17 published research papers last week alone. Take a closer look at some of the research…

Neurolucida:

Corson, J. A., & Erisir, A. (2013). Monosynaptic convergence of chorda tympani and glossopharyngeal afferents onto ascending relay neurons in the nucleus of the solitary tract: A high‐resolution confocal and correlative electron microscopy approach. Journal of Comparative Neurology. doi: 10.1002/cne.23357
Cova, L., Gelosa, P., Mura, E., Mauro, A., Stramba-Badiale, M., Michailidis, G., … & Zanchetti, A. (2013). Vascular and parenchymal lesions along with enhanced neurogenesis characterize the brain of asymptomatic stroke-prone spontaneous hypertensive rats. Journal of Hypertension, 31, 000-000. doi: 10.1097/HJH.0b013e3283619d7f
Crociara, P., Parolisi, R., Conte, D., Fumagalli, M., & Bonfanti, L. (2013). Cellular and Molecular Characterization of Multipolar Map5-Expressing Cells: A Subset of Newly Generated, Stage-Specific Parenchymal Cells in the Mammalian Central Nervous System. PLOS ONE, 8(5), e63258. doi:10.1371/journal.pone.0063258
Darling, W. G., Helle, N., Pizzimenti, M. A., Rotella, D. L., Hynes, S. M., Ge, J., … & Morecraft, R. J. (2013). Laterality affects spontaneous recovery of contralateral hand motor function following motor cortex injury in rhesus monkeys. Experimental Brain Research, 1-16. doi: 10.1007/s00221-013-3533-1 Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 5/6/13)” »

Take a Look at the Latest Research Using MBF Systems (week of 4/29/13)

Posted on May 9, 2013 by MBF Mindset

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Our systems were mentioned in 24 published research papers last week alone. Take a closer look at some of the research…

Neurolucida:

Badura, A., Schonewille, M., Voges, K., Galliano, E., Renier, N., Gao, Z., … & De Zeeuw, C. I. (2013). Climbing Fiber Input Shapes Reciprocity of Purkinje Cell Firing. Neuron.
Bony, G., Szczurkowska, J., Tamagno, I., Shelly, M., Contestabile, A., & Cancedda, L. (2013). Non-hyperpolarizing GABAB receptor activation regulates neuronal migration and neurite growth and specification by cAMP/LKB1. Nature Communications, 4, 1800. doi:10.1038/ncomms2820
Booker, S. A., Gross, A., Althof, D., Shigemoto, R., Bettler, B., Frotscher, M., … & Vida, I. (2013). Differential GABAB-Receptor-Mediated Effects in Perisomatic-and Dendrite-Targeting Parvalbumin Interneurons. The Journal of Neuroscience, 33(18), 7961-7974. doi: 10.1523/JNEUROSCI.1186-12.2013
Corson, J. A., & Erisir, A. (2013). Monosynaptic convergence of chorda tympani and glossopharyngeal afferents onto ascending relay neurons in the nucleus of the solitary tract: A high‐resolution confocal and correlative electron microscopy approach. Journal of Comparative Neurology. doi: 10.1002/cne.23357
Djogo, N., Jakovcevski, I., Müller, C., Lee, H. J., Xu, J. C., Jakovcevski, M., … & Schachner, M. (2013). Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer’s disease pathology in mice. Neurobiology of Disease. doi: 10.1016/j.nbd.2013.04.014 Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 4/29/13)” »

Take a Look at the Latest Research Using MBF Systems (week of 4/22/13)

Posted on May 2, 2013 by MBF Mindset

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Our systems were mentioned in 11 published research papers last week alone. Take a closer look at some of the research…

Neurolucida:

Harsan, L. A., Dávid, C., Reisert, M., Schnell, S., Hennig, J., von Elverfeldt, D., & Staiger, J. F. (2013). Mapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractography. Proceedings of the National Academy of Sciences. doi: 10.1073/pnas.1218330110
Ma, Y., Ramachandran, A., Ford, N., Parada, I., & Prince, D. A. (2013). Remodeling of dendrites and spines in the C1q knockout model of genetic epilepsy. Epilepsia. doi: 10.1111/epi.12195
Nonaka-Kinoshita, M., Reillo, I., Artegiani, B., Martínez-Martínez, M. Á., Nelson, M., Borrell, V., & Calegari, F. (2013). Regulation of cerebral cortex size and folding by expansion of basal progenitors. The EMBO Journal. doi:10.1038/emboj.2013.96
Sugihara, I., Brown, K. M., & Ascoli, G. A. (2013). New insights on vertebrate olivo-cerebellar climbing fibers from computerized morphological reconstructions. BioArchitecture, 3(2), 0-1. doi: 10.4161/bioa.24062

Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 4/22/13)” »

Take a Look at the Latest Research Using MBF Systems (week of 4/15/13)

Posted on April 25, 2013 by MBF Mindset

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Our systems were mentioned in 11 published research papers last week alone. Take a closer look at some of the research…

Stereo Investigator:

da Silveira, L. C., do Nascimento, L. F. R., Colquhoun, A., Abe, A. S., & de Souza, S. C. R. (2013). Cardiac hypertrophy and structural and metabolic remodeling related to seasonal dormancy in the first annual cycle in tegu lizards. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. doi: 10.1016/j.cbpa.2013.04.006
Dillingham, C. M., Guggenheim, J. A., & Erichsen, J. T. (2013). Disruption of the Centrifugal Visual System Inhibits Early Eye Growth in Chicks.Investigative Ophthalmology & Visual Science. doi: 10.1167/iovs.12-11548
El-Gohary, Y., Tulachan, S., Guo, P., Welsh, C., Wiersch, J., Prasadan, K., … & Gittes, G. (2013). Smad signaling pathways regulate pancreatic endocrine development. Developmental Biology. doi: 10.1016/j.ydbio.2013.04.003 Continue reading “Take a Look at the Latest Research Using MBF Systems (week of 4/15/13)” »

MBF Bioscience Website Wins Bronze at the 2012 Horizon Interactive Awards

Posted on April 23, 2013 by MBF Mindset

2012HorizonAward

We are delighted to announce that our new website, which launched in November 2012, won a bronze Horizon Interactive Award in the Health/Human Services category.

The Horizon Interactive Awards is an international awards competition that highlights the best interactive media solutions in the industry, from websites to online advertising and mobile solutions. They received over 1,000 entries for the 2012 competition from 25 countries.

Stereo Investigator System for Quantifying Neurotransmitter Switching in Human Brains Installed at Dr. Nicholas Spitzer’s Lab

Posted on April 22, 2013 by MBF Mindset

From left to right: Amy Guzdar, Dr. Nicholas Spitzer, Chris Douglas (in the back) and Dr. Claudia Alvarez-Baron.

Dr. Julie Korich, Staff Scientist/Research Liaison, recently installed a Stereo Investigator system on an existing Zeiss AxioSkop 2 motorized microscope for Dr. Nicholas Spitzer‘s lab at UC San Diego. She also provided training to the lab’s team for Stereo Investigator.

Dr. Spitzer is co-director of the Kavli Institute for Brain and Mind (UCSD). His research aims at understanding the roles of electrical activity in assembly of the nervous system by investigating the molecular mechanisms underlying neuronal differentiation.

Dr. Spitzer and his team are conducting studies on neurotransmitter specification. They are getting close to completing their first stereological study and will use Stereo Investigator to quantify neurotransmitter switching in the developing and adult brain.

You can also read about other studies involving the use of Stereo Investigator.